(Q41233331)

English

Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform

scientific article published on February 1996

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform (English)

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

author name string

Southan GJ

1

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Zingarelli B

2

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

O'Connor M

3

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Salzman AL

4

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Szabó C

5

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

language of work or name

0 references

publication date

1 February 1996

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

117

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

4

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

619-632

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

The multiple organ dysfunction syndrome caused by endotoxin in the rat: attenuation of liver dysfunction by inhibitors of nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

28 September 2017

The Croonian Lecture, 1993. The endothelium: maestro of the blood circulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

28 September 2017

Molecular mechanisms of nitric oxide regulation. Potential relevance to cardiovascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

28 September 2017

Nitric oxide synthase structure and mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

28 September 2017

Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

28 September 2017

Alterations in nitric oxide production in various forms of circulatory shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

28 September 2017

The mechanism of the inhibitory effect of polyamines on the induction of nitric oxide synthase: role of aldehyde metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

28 September 2017

Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

28 September 2017

Modulation of in vivo alloreactivity by inhibition of inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

28 September 2017

The high-output nitric oxide pathway: role and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

28 September 2017

Glutamate, nitric oxide and cell-cell signalling in the nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

28 September 2017

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

28 September 2017

Nitric oxide as a secretory product of mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

28 September 2017

Discrimination between citrulline and arginine transport in activated murine macrophages: inefficient synthesis of NO from recycling of citrulline to arginine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

14 June 2018

Activation of soluble guanylyl cyclase by a factor other than nitric oxide or carbon monoxide contributes to the vascular hyporeactivity to vasoconstrictor agents in the aorta of rats treated with endotoxin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

14 June 2018

Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

14 June 2018

Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

14 June 2018

Effects of guanidino and uremic compounds on nitric oxide pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

14 June 2018

Inhibition of nitric oxide formation by guanidines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

14 June 2018

Structure-activity relationship of alkylguanidines on smooth muscle organs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

14 June 2018

Nitric oxide synthesis in the CNS, endothelium and macrophages differs in its sensitivity to inhibition by arginine analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

14 June 2018

Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent and inhibited by arginine analogs with a rank-order of potency characteristic of activated macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

14 June 2018

Identification of inhibitors of nitric oxide synthase that do not interact with the endothelial cell L-arginine transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

14 June 2018

Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1909347

14 June 2018

Selective pharmacological inhibition of distinct nitric oxide synthase isoforms

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.1996.TB15236.X

21 January 2018

The mechanism of action of AET. IV. The distribution and the chemical forms of 2-mercaptoethylguanidine and bis(2-guanidoethyl) disulfide in protected mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8646406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel potent and selective inhibitors of inducible nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8646406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-activity relationships of amidine derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/8646406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical protection against ionizing radiation. III. Mercaptoalkylguanidines and related isothiuronium compounds with protective activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/8646406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of NG-methyl-L-arginine, NG-nitro-L-arginine, and aminoguanidine on constitutive and inducible nitric oxide synthase in rat aorta

1 reference

https://pubmed.ncbi.nlm.nih.gov/8646406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and radioprotective effect of AET and MEG in organism

1 reference

https://pubmed.ncbi.nlm.nih.gov/8646406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo radiation protection by nitric oxide modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8646406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiation-protective Agents.I. Studies on N-Alkylated-2-(2-aminoethyl)thiopseudoureas and 1, 1-(Dithioethylene)diguanidines

1 reference

https://pubmed.ncbi.nlm.nih.gov/8646406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibition of the inducible nitric oxide synthase by aminoguanidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8646406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage and endothelial cell nitric oxide synthesis: cell-type selective inhibition by NG-aminoarginine, NG-nitroarginine and NG-methylarginine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8646406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of sulfhydryl groups with 2,2′- or 4,4′-dithiodipyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8646406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminoguanidine is an isoform-selective, mechanism-based inactivator of nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8646406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.1996.TB15236.X

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

ResearchGate publication ID

0 references

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