(Q41237231)

English

Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells

scientific article published on December 1990

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells (English)

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

author name string

Yamashita K

1

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Yasuda H

2

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Pines J

3

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Yasumoto K

4

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Nishitani H

5

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Ohtsubo M

6

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Hunter T

7

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Sugimura T

8

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Nishimoto T

9

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

language of work or name

0 references

publication date

1 December 1990

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

The EMBO Journal

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Europe PubMed Central

PMC publication ID

28 September 2017

9

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

13

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

4331-4338

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Monoclonal antibodies to mitotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Hyperphosphorylation of N-60, a protein structurally and immunologically related to nucleolin after tumour-promoter treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Cell cycle control genes in fission yeast and mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Maturation-promoting factor and the regulation of the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Involvement of protein phosphatases 1 and 2A in the control of M phase-promoting factor activity in starfish

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Cyclin synthesis drives the early embryonic cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

M phase-promoting factor: its identification as the M phase-specific H1 histone kinase and its activation by dephosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Protein phosphatases come of age

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Cyclin is a component of the sea urchin egg M-phase specific histone H1 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

The structure and regulation of protein phosphatases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Control of the higher eukaryote cell cycle by p34cdc2 homologues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

MPF from starfish oocytes at first meiotic metaphase is a heterodimer containing one molecule of cdc2 and one molecule of cyclin B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Mutations of phosphorylation sites in lamin A that prevent nuclear lamina disassembly in mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Identification of cell cycle-regulated phosphorylation sites on nuclear lamin C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Cdc2 H1 kinase is negatively regulated by a type 2A phosphatase in the Xenopus early embryonic cell cycle: evidence from the effects of okadaic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Universal control mechanism regulating onset of M-phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Cyclin is a component of maturation-promoting factor from Xenopus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Movement and segregation of kinetochores experimentally detached from mammalian chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

28 September 2017

Smooth muscle myosin phosphatase inhibition and force enhancement by black sponge toxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

14 June 2018

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

14 June 2018

Translation of cyclin mRNA is necessary for extracts of activated xenopus eggs to enter mitosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

14 June 2018

Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

14 June 2018

Regulation of microtubule dynamics by cdc2 protein kinase in cell-free extracts of Xenopus eggs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

14 June 2018

Microinjection of p34cdc2 kinase induces marked changes in cell shape, cytoskeletal organization, and chromatin structure in mammalian fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

14 June 2018

Differential phosphorylation of c-Abl in cell cycle determined by cdc2 kinase and phosphatase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

14 June 2018

Premature of chromosome condensation in a ts DNA- mutant of BHK cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

14 June 2018

The bimG gene of Aspergillus nidulans, required for completion of anaphase, encodes a homolog of mammalian phosphoprotein phosphatase 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

17 June 2018

Regulation of MPF activity in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

19 August 2018

Fission yeast p13 blocks mitotic activation and tyrosine dephosphorylation of the Xenopus cdc2 protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

19 August 2018

Under arrest in the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=552219

30 September 2018

Activation of M-phase-specific histone H1 kinase by modification of the phosphorylation of its p34cdc2 and cyclin components

1 reference

https://pubmed.ncbi.nlm.nih.gov/2176149

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2176149

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caffeine-induced uncoupling of mitosis from the completion of DNA replication in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2176149

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoregulation of tubulin expression is achieved through specific degradation of polysomal tubulin mRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/2176149

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/2176149

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of cdc2 protein kinase during mitosis in human cells: cell cycle-dependent phosphorylation and subunit rearrangement

1 reference

https://pubmed.ncbi.nlm.nih.gov/2176149

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/2176149

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cdc2 protein kinase is complexed with both cyclin A and B: evidence for proteolytic inactivation of MPF

1 reference

https://pubmed.ncbi.nlm.nih.gov/2176149

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Okadaic acid, a specific protein phosphatase inhibitor, induces maturation and MPF formation in Xenopus laevis oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2176149

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of MPF from starfish: identification as the H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2176149

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synthesis of protein(S) for chromosome condensation may be regulated by a post-transcriptional mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/2176149

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2176149

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dephosphorylation and activation of Xenopusp34 cdc2 protein kinase during the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/2176149

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

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