(Q41243147)

28 September 2017

1 reference

title

Analysis of resistance mutants of viral polymerases (English)

1 reference

28 September 2017

Oxford JS

1

1 reference

28 September 2017

al-Jabri AA

series ordinal

2

1 reference

28 September 2017

Stein CA

series ordinal

3

1 reference

28 September 2017

Levantis P

series ordinal

4

1 reference

28 September 2017

language of work or name

English

0 references

publication date

1 January 1996

1 reference

28 September 2017

Methods in Enzymology

1 reference

28 September 2017

275

1 reference

28 September 2017

555-600

1 reference

In vivo Selection of an Influenza A2 Strain resistant to Amantadine

28 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Isolation and Characterization of Acyclovir-resistant Mutants of Herpes Simplex Virus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Isolation of drug-resistant variants of HIV-1 from patients on long-term zidovudine therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Zidovudine sensitivity of human immunodeficiency viruses from high-risk, symptom-free individuals during therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Sequence analysis of an HIV-1 isolate which displays unusually high-level AZT resistance in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Sequence analysis of proviral HIV RT amplified directly by a semi-quantitative technique from AZT treated patients

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

An improved method for directly sequencing PCR amplified material using dimethyl sulphoxide

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Molecular aspects of AZT resistance in HIV1

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Prevalence of Resistance in Patients Receiving Ganciclovir for Serious Cytomegalovirus Infection

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Rapid development of drug-resistant mutants of poliovirus.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Molecular mechanisms of drug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Membrane proteins specified by herpes simplex viruses. III. Role of glycoprotein VP7(B2) in virion infectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

The Sensitivity of Acyclovir-Resistant Mutants of Herpes Simplex Virus to Other Antiviral Drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Novel substrate of adenosine deaminase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Biological activities of some purine arabinosides

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

9-(2-Hydroxyethoxymethyl)guanine activity against viruses of the herpes group

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

In vitro susceptibility of varicella-zoster virus to acyclovir

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Evidence that the 'active centre' of the herpes simplex virus thymidine kinase involves an interaction between three distinct regions of the polypeptide

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Nucleotide sequence changes in thymidine kinase gene of herpes simplex virus type 2 clones from an isolate of a patient treated with acyclovir

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Characterization of a DNA polymerase mutant of herpes simplex virus from a severely immunocompromised patient receiving acyclovir

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

In vitro and in vivo resistance of herpes simplex virus to 9-(2-hydroxyethoxymethyl)guanine (acycloguanosine)

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Altered substrate specificity of herpes simplex virus thymidine kinase confers acyclovir-resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Induction of both thymidine and deoxycytidine kinase activity by herpes viruses.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Development of clinical resistance to acyclovir in herpes simplex virus-infected mice receiving oral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Virus drug-resistance: mechanisms and consequences

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Cooperative effects between two acyclovir resistance loci in herpes simplex virus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Crystal structures of the thymidine kinase from herpes simplex virus type-1 in complex with deoxythymidine and ganciclovir

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

The complete DNA sequence of varicella-zoster virus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Fowlpox virus thymidine kinase: nucleotide sequence and relationships to other thymidine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Human thymidine kinase gene: molecular cloning and nucleotide sequence of a cDNA expressible in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Molecular cloning and structural analysis of murine thymidine kinase genomic and cDNA sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Structure and expression of the Chinese hamster thymidine kinase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

The nucleotide sequence of the chicken thymidine kinase gene and the relationship of its predicted polypeptide to that of the vaccinia virus thymidine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Homology between human bladder carcinoma oncogene product and mitochondrial ATP-synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Cloning of the marmoset herpesvirus thymidine kinase gene and analyses of the boundaries of the coding region

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

MUTANT STRAINS OF HERPES SIMPLEX DEFICIENT IN THYMIDINE KINASE-INDUCING ACTIVITY

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Analysis of the bovine herpesvirus type 1 thymidine kinase (TK) gene from wild-type virus and TK-deficient mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Clinical isolate of herpes simplex virus type 2 that induces a thymidine kinase with altered substrate specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

DNA sequence and expression of the B95-8 Epstein-Barr virus genome.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

DNA sequence of the region in the genome of herpes simplex virus type 1 containing the genes for DNA polymerase and the major DNA binding protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Primary structural relationships may reflect similar DNA replication strategies

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Activity of 9-(1,3-dihydroxy-2-propoxymethyl)guanine compared with that of acyclovir against human, monkey, and rodent cytomegaloviruses

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Plaque autoradiography assay for the detection and quantitation of thymidine kinase-deficient and thymidine kinase-altered mutants of herpes simplex virus in clinical isolates

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Sensitivity monitoring of herpes simplex virus isolates from patients receiving acyclovir

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Herpes simplex virus resistant to acyclovir. A study in a tertiary care center

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

The pathogenicity of drug-resistant variants of herpes simplex virus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Pathogenicity of acyclovir-resistant herpes simplex virus type 1 from an immunodeficient child

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Herpes simplex virus type 2 meningoencephalitis resistant to acyclovir in a patient with AIDS.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Acyclovir-resistant herpes simplex virus infections in patients with the acquired immunodeficiency syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Isolation and characterisation of resistant Herpes simplex virus after acyclovir therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Intravenous acyclovir to treat mucocutaneous herpes simplex virus infection after marrow transplantation: a double-blind trial

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Herpes simplex virus variants restraint to high concentrations of acyclovir exist in clinical isolates

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Characterisation of acyclovir-resistant and -sensitive clinical herpes simplex virus isolates from an immunocompromised patient

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Acyclovir-resistant herpes simplex virus infection due to altered DNA polymerase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Severe, progressive herpetic whitlow caused by an acyclovir-resistant virus in a patient with AIDS.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Successful treatment with foscarnet of an acyclovir-resistant mucocutaneous infection with herpes simplex virus in a patient with acquired immunodeficiency syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

RNA-directed DNA synthesis and RNA tumor viruses

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Administration of 3'-azido-3'-deoxythymidine, an inhibitor of HTLV-III/LAV replication, to patients with AIDS or AIDS-related complex

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

In vivo activity against HIV and favorable toxicity profile of 2',3'-dideoxyinosine

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

In vitro toxicity and metabolism of 2',3'-dideoxycytidine, an inhibitor of human immunodeficiency virus infectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Detection, quantification and sequencing of HIV-1 from the plasma of seropositive individuals and from factor VIII concentrates

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Potential target sites for antiviral inhibitors of human immunodeficiency virus (HIV).

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Structure of HIV-1 reverse transcriptase/DNA complex at 7 A resolution showing active site locations

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Human immunodeficiency virus I-induced expression of P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Site-specific mutagenesis of AIDS virus reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

The clinical significance of antiviral drug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Ordered appearance of zidovudine resistance mutations during treatment of 18 human immunodeficiency virus-positive subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Markers for HIV-disease progression in untreated patients and patients receiving AZT: Evaluation of viral activity, AZT resistance, serum cholesterol, β2-microglobulin, CD4+ cell counts, and HIV antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

High-level resistance to (-) enantiomeric 2'-deoxy-3'-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine confers high-level resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Comprehensive mutant enzyme and viral variant assessment of human immunodeficiency virus type 1 reverse transcriptase resistance to nonnucleoside inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

[2',5'-Bis-O-(tert-butyldimethylsilyl)]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) (TSAO) derivatives of purine and pyrimidinenucleosides as potent and selective inhibitors of human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Activity of a novel quinoxaline derivative against human immunodeficiency virus type 1 reverse transcriptase and viral replication

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Identification of four conserved motifs among the RNA-dependent polymerase encoding elements

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Interactions between drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

The clinical significance of drug-resistance mutants of human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Detection of Mutations Associated with Zidovudine Resistance in Human Immunodeficiency Virus by Use of the Polymerase Chain Reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Zidovudine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Use of evolutionary limitations of HIV-1 multidrug resistance to optimize therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Convergent combination therapy can select viable multidrug-resistant HIV-1 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

HIV-1 error revealed.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

5-chloro-3-(phenylsulfonyl)indole-2-carboxamide: a novel, non-nucleoside inhibitor of HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Possible involvement of cell fusion and viral recombination in generation of human immunodeficiency virus variants that display dual resistance to AZT and 3TC

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Viral dynamics in human immunodeficiency virus type 1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Allogeneic leukocytes as a possible factor in induction of aids in homosexual men

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

HLA mimicry by HIV-1 gp120 in the pathogenesis of AIDS

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Pathogenicity of herpes simplex virus mutants containing drug resistance mutations in the viral DNA polymerase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Evidence that herpes simplex virus DNA is transcribed by cellular RNA polymerase B

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Mutations in the herpes simplex virus DNA polymerase gene can confer resistance to 9-beta-D-arabinofuranosyladenine

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

A single-base change within the DNA polymerase locus of herpes simplex virus type 2 can confer resistance to aphidicolin

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Zidovudine resistance predicted by direct detection of mutations in DNA from HIV-infected lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

Resistance pattern of human immunodeficiency virus type 1 reverse transcriptase to quinoxaline S-2720

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975031-0

7 January 2021

10.1016/S0076-6879(96)75031-0

Identifiers

DOI

1 reference

28 September 2017

1 reference