(Q41259301)

28 September 2017

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title

Mechanisms of beta-adrenergic receptor desensitization: from molecular biology to heart failure (English)

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28 September 2017

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M J Lohse

1

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28 September 2017

S Engelhardt

series ordinal

2

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28 September 2017

S Danner

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3

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28 September 2017

M Böhm

series ordinal

4

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28 September 2017

1 January 1996

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Basic Research in Cardiology

28 September 2017

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28 September 2017

91 Suppl 2

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28 September 2017

29-34

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https://scigraph.springernature.com/pub.10.1007/bf00795359

28 September 2017

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cites work

Increased messenger RNA level of the inhibitory G protein alpha subunit Gi alpha-2 in human end-stage heart failure

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12 December 2020

Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors

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12 December 2020

Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments

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12 December 2020

Association of hepatic beta 2-adrenergic receptor gene transcript destabilization during postnatal development in the Sprague-Dawley rat with a M(r) 85,000 protein that binds selectively to the beta 2-adrenergic receptor mRNA 3'-untranslated region

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12 December 2020

Structure and mechanism of the G protein-coupled receptor kinases.

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12 December 2020

The role of G-protein beta gamma subunits in signal transduction

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12 December 2020

Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts

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12 December 2020

Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality. CONSENSUS Trial Study Group

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12 December 2020

Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family

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12 December 2020

Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors

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12 December 2020

Reduced beta-adrenergic receptor activation decreases G-protein expression and beta-adrenergic receptor kinase activity in porcine heart

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12 December 2020

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12 December 2020

Phosphorylation of the mammalian beta-adrenergic receptor by cyclic AMP-dependent protein kinase. Regulation of the rate of receptor phosphorylation and dephosphorylation by agonist occupancy and effects on coupling of the receptor to the stimulator

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12 December 2020

Myocardial beta-adrenergic receptor function during the development of pacing-induced heart failure

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12 December 2020

Beta-adrenergic agonists that down-regulate receptor mRNA up-regulate a M(r) 35,000 protein(s) that selectively binds to beta-adrenergic receptor mRNAs

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12 December 2020

Activation by G protein beta gamma subunits of agonist- or light-dependent phosphorylation of muscarinic acetylcholine receptors and rhodopsin

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12 December 2020

Agonist and cyclic AMP-mediated regulation of beta 1-adrenergic receptor mRNA and gene transcription in rat C6 glioma cells.

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12 December 2020

Differences in beta-adrenergic neuroeffector mechanisms in ischemic versus idiopathic dilated cardiomyopathy

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12 December 2020

Specific enhancement of beta-adrenergic receptor kinase activity by defined G-protein beta and gamma subunits

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12 December 2020

Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart

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12 December 2020

beta-Arrestin: a protein that regulates beta-adrenergic receptor function

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12 December 2020

Model systems for the study of seven-transmembrane-segment receptors

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12 December 2020

Arresting G-protein coupled receptor activity.

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12 December 2020

The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase

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12 December 2020

Cone arrestin identified by targeting expression of a functional family

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12 December 2020

Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase

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12 December 2020

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor

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12 December 2020

Molecular mechanisms of membrane receptor desensitization.

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12 December 2020

Beta-adrenergic receptor kinase. Agonist-dependent receptor binding promotes kinase activation

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12 December 2020

Inhibition of beta-adrenergic receptor kinase prevents rapid homologous desensitization of beta 2-adrenergic receptors

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12 December 2020

Primary and secondary structure of bovine retinal S antigen (48-kDa protein).

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12 December 2020

Dual regulation by G proteins of agonist-dependent phosphorylation of muscarinic acetylcholine receptors.

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12 December 2020

Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level

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12 December 2020

Regulation of receptor expression by agonists: transcriptional and post-transcriptional controls

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12 December 2020

Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.

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12 December 2020

Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors

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12 December 2020

The M(r) 35,000 beta-adrenergic receptor mRNA-binding protein binds transcripts of G-protein-linked receptors which undergo agonist-induced destabilization

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12 December 2020

Increase of the 40,000-mol wt pertussis toxin substrate (G protein) in the failing human heart

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12 December 2020

Modulation of adrenergic receptors and G-transduction proteins in failing human ventricular myocardium

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12 December 2020

Agonist-induced destabilization of beta-adrenergic receptor mRNA. Attenuation of glucocorticoid-induced up-regulation of beta-adrenergic receptors

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12 December 2020

Receptor-to-effector signaling through G proteins: roles for beta gamma dimers as well as alpha subunits

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12 December 2020

Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase

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12 December 2020

Rhodopsin, photoreceptor of the rod cell. An emerging pattern for structure and function

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12 December 2020

Beta-adrenoceptors in cardiac disease

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12 December 2020

Mechanism of beta-adrenergic receptor kinase activation by G proteins

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12 December 2020

Turning off the signal: desensitization of beta-adrenergic receptor function

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12 December 2020

Structural heterogeneity of membrane receptors and GTP-binding proteins and its functional consequences for signal transduction

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12 December 2020

Ligand-regulated internalization and recycling of human beta 2-adrenergic receptors between the plasma membrane and endosomes containing transferrin receptors

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12 December 2020

Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms

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12 December 2020

Reduced beta 1 receptor messenger RNA abundance in the failing human heart

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12 December 2020

Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems

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12 December 2020

G-protein-coupled receptor kinases and the heart.

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12 December 2020

The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain

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12 December 2020

Sequestration and recycling of beta 2-adrenergic receptors permit receptor resensitization

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12 December 2020

Pleckstrin homology domain-mediated membrane association and activation of the beta-adrenergic receptor kinase requires coordinate interaction with G beta gamma subunits and lipid

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12 December 2020

Down-regulation of beta-adrenergic receptors: agonist-induced reduction in receptor mRNA levels

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12 December 2020

Downregulation of adenylylcyclase types V and VI mRNA levels in pacing-induced heart failure in dogs

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12 December 2020

Beta-adrenergic neuroeffector abnormalities in the failing human heart are produced by local rather than systemic mechanisms

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12 December 2020

Increase of Gi alpha in human hearts with dilated but not ischemic cardiomyopathy

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12 December 2020

Identifiers

DOI

10.1007/BF00795359

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28 September 2017

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