(Q41261282)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8958916%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

review article

1 reference

title

Signal transduction by interleukin-12 and interleukin-2. A comparison and contrast (English)

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21 October 2019

1

1 reference

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21 October 2019

author name string

S S Cho

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8958916%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

J J O'Shea

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8958916%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

language of work or name

English

0 references

publication date

1 October 1996

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8958916%20AND%20SRC:MED&resulttype=core&format=json

Annals of the New York Academy of Sciences

21 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8958916%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

volume

795

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8958916%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

page(s)

41-59

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8958916%20AND%20SRC:MED&resulttype=core&format=json

Interleukin-2: inception, impact, and implications

21 October 2019

cites work

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Interleukin-2 induction of T-cell G1 progression and c-myb expression

21 January 2018

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21 January 2018

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Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor alpha production

21 January 2018

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Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts

21 January 2018

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Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

21 January 2018

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Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells

21 January 2018

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Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor

21 January 2018

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Homology of the p40 subunit of natural killer cell stimulatory factor (NKSF) with the extracellular domain of the interleukin-6 receptor

21 January 2018

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Structural design and molecular evolution of a cytokine receptor superfamily

21 January 2018

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The hematopoietin receptor superfamily

21 January 2018

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Molecular cloning and expression of cDNAs for the human interleukin-2 receptor

21 January 2018

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Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's

21 January 2018

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Cloning of the gamma chain of the human IL-2 receptor

21 January 2018

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Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor

21 January 2018

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Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor

21 January 2018

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Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

21 January 2018

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Heterodimerization of the IL-2 receptor beta- and gamma-chain cytoplasmic domains is required for signalling

21 January 2018

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Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T-cell proliferation.

21 January 2018

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Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

21 January 2018

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An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: A cytokine receptor superfamily oncogene

21 January 2018

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Growth factor signaling by receptor tyrosine kinases

21 January 2018

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Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12

21 January 2018

1 reference

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Differential effects of tyrosine kinase inhibition in CD69 antigen expression and lytic activity induced by rIL-2, rIL-12, and rIFN-alpha in human NK cells

21 January 2018

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Jaks and Stats in signaling by the cytokine receptor superfamily

21 January 2018

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Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes

21 January 2018

1 reference

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A protein tyrosine kinase in the interferon alpha/beta signaling pathway

21 January 2018

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Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway

21 January 2018

1 reference

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Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.

21 January 2018

1 reference

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Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

21 January 2018

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Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15

21 January 2018

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Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

21 January 2018

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Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits

21 January 2018

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Involvement of p59fynT in interleukin-5 receptor signaling

21 January 2018

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IL-2 signaling: recruitment and activation of multiple protein tyrosine kinases by the components of the IL-2 receptor

21 January 2018

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Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway

21 January 2018

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Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

21 January 2018

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

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Transcription factors in interferon signaling

21 January 2018

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Stat3 and Stat4: members of the family of signal transducers and activators of transcription

21 January 2018

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An interleukin-4-induced transcription factor: IL-4 Stat

21 January 2018

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Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process

21 January 2018

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Components of a Stat recognition code: evidence for two layers of molecular selectivity

21 January 2018

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Phosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor

21 January 2018

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The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

21 January 2018

1 reference

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Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission

21 January 2018

1 reference

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Protein-tyrosine kinase-dependent activation of STAT transcription factors in interleukin-2- or interleukin-4-stimulated T lymphocytes

21 January 2018

1 reference

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Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity

21 January 2018

1 reference

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Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes

21 January 2018

1 reference

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Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

Interleukin-2-triggered Raf-1 expression, phosphorylation, and associated kinase activity increase through G1 and S in CD3-stimulated primary human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

Interleukin 2 activates extracellular signal-regulated protein kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

The Src-family kinase, Fyn, regulates the activation of phosphatidylinositol 3-kinase in an interleukin 2-responsive T cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

Role of IRS-2 in insulin and cytokine signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases

21 January 2018

1 reference

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Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

The molecular basis of X-linked severe combined immunodeficiency: the role of the interleukin-2 receptor gamma chain as a common gamma chain, gamma c.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans

21 January 2018

1 reference

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Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

21 January 2018

1 reference

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Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

Developmental commitment to the Th2 lineage by extinction of IL-12 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

Antitumor and antimetastatic activity of interleukin 12 against murine tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin 12 and Pentostam

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

Phosphorylation of src Family lck Tyrosine Kinase Following Interleukin-12 Activation of Human Natural Killer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB52654.X

10.1111/J.1749-6632.1996.TB52654.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8958916%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

1 reference