(Q41261556)

28 September 2017

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title

Extrapolation from animals to man. The integration of pharmacokinetics and pharmacodynamics (English)

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28 September 2017

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Campbell DB

1

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28 September 2017

language of work or name

English

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publication date

1 October 1996

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Annals of the New York Academy of Sciences

28 September 2017

published in

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28 September 2017

volume

801

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28 September 2017

page(s)

116-135

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A unified framework for using neural networks to build QSARs

28 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Relationship between morphine analgesia and cortical extracellular fluid levels of morphine and its metabolites in the rat: a microdialysis study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Application of artificial neural networks to clinical medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Neural network predicted peak and trough gentamicin concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Effects of short- and long-term administration of fluoxetine on the monoamine content of rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Comparison of canine and human gastrointestinal physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Some Fecundity and Longevity Records for Captive Small Mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Structure-localization relationships of 11C-labeled phentermine derivatives: effect of aromatic substitution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Studies on a recent class of network models of the immune system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Structural basis for species-specific differences in the phosphorylation of Na,K-ATPase by protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Cellular basis for the species differences in sensitivity to cardiac glycosides (digitalis).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Non-congeneric structure-pharmacokinetic property correlation studies using fuzzy adaptive least-squares: volume of distribution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Species differences in 5-HT2A receptors: cloned pig and rhesus monkey 5-HT2A receptors reveal conserved transmembrane homology to the human rather than rat sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Fluoxetine and trifluoperazine in human brain: a 19F-nuclear magnetic resonance spectroscopy study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Mechanisms of hepatocarcinogenicity of peroxisome-proliferating drugs and chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Pharmacokinetics and brain entry of alaptide, a novel nootropic agent, in mice, rats and rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Cloned adenosine A3 receptors: pharmacological properties, species differences and receptor functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Species differences in the cardiovascular responses to histamine H3 receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Comparative studies on the anorectic activity of d-fenfluramine in mice, rats, and guinea pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

alpha 1-Adrenoceptors in the mammalian brain: similar pharmacology but different distribution in rodents and primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Integration of animal pharmacokinetic and pharmacodynamic data in drug safety assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Neural networks in pharmacodynamic modeling. Is current modeling practice of complex kinetic systems at a dead end?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

Coexistence of three β-adrenoceptor subtypes in white fat cells of various mammalian species

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1996.TB17436.X

10.1111/J.1749-6632.1996.TB17436.X

21 January 2018

Identifiers

DOI

1 reference

28 September 2017

1 reference