(Q41263744)

28 September 2017

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title

The DNA-dependent protein kinase, DNA-PK: 10 years and no ends in sight (English)

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28 September 2017

Lees-Miller SP

1

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28 September 2017

1 January 1996

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Biochemistry and Cell Biology

28 September 2017

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28 September 2017

74

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28 September 2017

503-512

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28 September 2017

4

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Dimerization and DNA binding alter phosphorylation of Fos and Jun.

28 September 2017

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Absence of autoantigen Ku in mature human neutrophils and human promyelocytic leukemia line (HL-60) cells and lymphocytes undergoing apoptosis

21 January 2018

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Characterization of the 70kDa component of the human Ku autoantigen expressed in insect cell nuclei using a recombinant baculovirus vector

21 January 2018

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c-Jun is phosphorylated by the DNA-dependent protein kinase in vitro; definition of the minimal kinase recognition motif

21 January 2018

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A Drosophila protein homologous to the human p70 Ku autoimmune antigen interacts with the P transposable element inverted repeats

21 January 2018

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scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair

21 January 2018

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Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

21 January 2018

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scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase

21 January 2018

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The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication

21 January 2018

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Chromosomal location and expression of the genes coding for Ku p70 and p80 in human cell lines and normal tissues.

21 January 2018

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A DNA-activated protein kinase from HeLa cell nuclei

21 January 2018

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DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis

21 January 2018

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Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death

21 January 2018

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Role of a major autoepitope in forming the DNA binding site of the p70 (Ku) antigen

21 January 2018

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The BCL2 major breakpoint region is a sequence- and cell-cycle-specific binding site of the Ku antigen

21 January 2018

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Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II

21 January 2018

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Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants

21 January 2018

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DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair

21 January 2018

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The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

21 January 2018

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Protein kinases and DNA damage

21 January 2018

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DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

21 January 2018

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RPA involvement in the damage-recognition and incision steps of nucleotide excision repair

21 January 2018

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Enhancer 1 binding factor, a Ku-related protein, is a positive regulator of RNA polymerase I transcription initiation

21 January 2018

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When is a lipid kinase not a lipid kinase? When it is a protein kinase

21 January 2018

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DNA-activated protein kinase in Raji Burkitt's lymphoma cells

21 January 2018

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DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK.

21 January 2018

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GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

21 January 2018

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Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.

21 January 2018

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DNA-dependent protein kinase specifically represses promoter-directed transcription initiation by RNA polymerase I.

21 January 2018

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Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

21 January 2018

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Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

21 January 2018

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Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositis-scleroderma overlap

21 January 2018

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Isolation and characterization of cDNA encoding the 80-kDa subunit protein of the human autoantigen Ku (p70/p80) recognized by autoantibodies from patients with scleroderma-polymyositis overlap syndrome

21 January 2018

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Production and characterization of recombinant human Ku antigen

21 January 2018

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Phosphorylation of the p34 subunit of human single-stranded-DNA-binding protein in cyclin A-activated G1 extracts is catalyzed by cdk-cyclin A complex and DNA-dependent protein kinase

21 January 2018

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Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells

21 January 2018

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A DNA end-binding factor involved in double-strand break repair and V(D)J recombination

21 January 2018

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Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks

21 January 2018

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Gene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8

21 January 2018

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The possible involvement of DNA-dependent protein kinase in the phosphorylation of P1 protein in cell-free DNA replication of Xenopus eggs.

21 January 2018

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DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA.

21 January 2018

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Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

21 January 2018

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Nomenclature of human genes involved in ionizing radiation sensitivity.

21 January 2018

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Phosphorylation at Ser-15 and Ser-392 in mutant p53 molecules from human tumors is altered compared to wild-type p53

21 January 2018

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The molecular biology of apoptosis

21 January 2018

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Molecular properties, substrate specificity and regulation of DNA-dependent protein kinase from Raji Burkitt's lymphoma cells

21 January 2018

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Life, death, and the pursuit of apoptosis.

21 January 2018

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Equine severe combined immunodeficiency: a defect in V(D)J recombination and DNA-dependent protein kinase activity.

21 January 2018

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Phosphorylation of protein tau by double-stranded DNA-dependent protein kinase.

21 January 2018

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Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

21 January 2018

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Purification of an 86-70 kDa nuclear DNA-associated protein complex.

21 January 2018

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21 January 2018

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Sequence-specific DNA binding by Ku autoantigen and its effects on transcription

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/O96-054

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28 September 2017

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PubMed ID

8960356