(Q41295156)

29 September 2017

title

Studies on Deimmunization of Antileukaemic L-Asparaginase to have Reduced Clinical Immunogenicity--An in silico Approach (English)

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29 September 2017

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L N Ramya

1

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29 September 2017

Krishna Kanth Pulicherla

series ordinal

2

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29 September 2017

publication date

6 March 2015

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Pathology Oncology Research

29 September 2017

published in

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29 September 2017

volume

21

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29 September 2017

issue

4

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29 September 2017

page(s)

909-920

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Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell toxicity.

29 September 2017

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21 January 2018

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Therapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral drift

21 January 2018

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21 January 2018

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21 January 2018

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A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach

21 January 2018

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Erwinia chrysanthemi L-asparaginase: epitope mapping and production of antigenically modified enzymes

21 January 2018

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Optimized Hydrophobic Interactions and Hydrogen Bonding at the Target-Ligand Interface Leads the Pathways of Drug-Designing

21 January 2018

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21 January 2018

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21 January 2018

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12 December 2020

Erwinia asparaginase after allergy to E. coli asparaginase in children with acute lymphoblastic leukemia

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12 December 2020

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12 December 2020

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12 December 2020

Phase I trial of 177lutetium-labeled J591, a monoclonal antibody to prostate-specific membrane antigen, in patients with androgen-independent prostate cancer

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12 December 2020

Assessment of physical process conditions for enhanced production of novel glutaminase-free L-asparaginase from Pectobacterium carotovorum MTCC 1428

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12 December 2020

Anti-Erwinia asparaginase antibodies during treatment of childhood acute lymphoblastic leukemia and their relationship to outcome: a case-control study

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12 December 2020

Purification, characterization and antitumor activity of L-asparaginase isolated from Pseudomonas stutzeri MB-405

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12 December 2020

A new L-asparaginase with antitumour activity?

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12 December 2020

The cross-reactivity of anti-asparaginase antibodies against different L-asparaginase preparations

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12 December 2020

Fitting a mixture model by expectation maximization to discover motifs in biopolymers

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12 December 2020

A pharmacological study on pegylated asparaginase used in front-line treatment of children with acute lymphoblastic leukemia

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12 December 2020

Probing the antigenicity of E. coli L-asparaginase by mutational analysis.

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12 December 2020

Circumventing immunogenicity in the development of therapeutic antibodies

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12 December 2020

Treatment of L5178Y tumor-bearing BDF1 mice with a nonimmunogenic L-glutaminase-L-asparaginase

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12 December 2020

The significance of lysosomes in pathology and medicine

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12 December 2020

Evaluation of immunologic crossreaction of antiasparaginase antibodies in acute lymphoblastic leukemia (ALL) and lymphoma patients

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12 December 2020

In silico engineering of L-asparaginase to have reduced glutaminase side activity for effective treatment of acute lymphoblastic leukemia

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12 December 2020

Probing the role of threonine and serine residues of E. coli asparaginase II by site-specific mutagenesis

1 reference

12 December 2020

10.1007/S12253-015-9912-0

Identifiers

DOI

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29 September 2017

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