(Q41296024)

29 September 2017

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title

Drug delivery issues in vaccine development (English)

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29 September 2017

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M F Powell

1

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29 September 2017

1 December 1996

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29 September 2017

Pharmaceutical Research

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29 September 2017

13

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29 September 2017

12

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29 September 2017

1777-1785

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Reduction of disulfide bonds within lysosomes is a key step in antigen processing

29 September 2017

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12 December 2020

Human immunodeficiency virus neutralizing antibodies recognize several conserved domains on the envelope glycoproteins

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12 December 2020

Deficient T-cell responses in non-responders to hepatitis B vaccination: absence of TH1 cytokine production

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12 December 2020

Vaccine-associated poliomyelitis in the United States, 1961-1972

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12 December 2020

Vaccinology of poliomyelitis

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12 December 2020

Treatment of metastatic melanoma with an autologous tumor-cell vaccine: clinical and immunologic results in 64 patients.

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12 December 2020

Gene introduction into animal tissues

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12 December 2020

Invariant chain can function as a chaperone protein for class II major histocompatibility complex molecules

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12 December 2020

Priming immunization determines T helper cytokine mRNA expression patterns in lungs of mice challenged with respiratory syncytial virus

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12 December 2020

How many injections of poliomyelitis vaccine for effective and durable immunity

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12 December 2020

Immunizations: Current controversies

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12 December 2020

Direct gene transfer into nonhuman primate myofibers in vivo

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12 December 2020

DNA vaccines: a novel approach to immunization.

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12 December 2020

Temporal analysis of the antibody response to HIV envelope protein in HIV-infected laboratory workers

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12 December 2020

Protection against malaria by immunization with a Plasmodium yoelii circumsporozoite protein nucleic acid vaccine.

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12 December 2020

Development of a single-shot subunit vaccine for HIV-1. 2. Defining optimal autoboost characteristics to maximize the humoral immune response

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12 December 2020

Saponin adjuvant enhancement of antigen-specific immune responses to an experimental HIV-1 vaccine

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12 December 2020

Saponin adjuvant induction of ovalbumin-specific CD8+ cytotoxic T lymphocyte responses

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12 December 2020

Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160.

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12 December 2020

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12 December 2020

Interaction of MHC class I molecules with the transporter associated with antigen processing

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12 December 2020

Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex

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12 December 2020

VARIATIONS IN AFFINITIES OF ANTIBODIES DURING THE IMMUNE RESPONSE

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12 December 2020

Development of a single-shot subunit vaccine for HIV-1. 3. Effect of adjuvant and immunization schedule on the duration of the humoral immune response to recombinant MN gp120.

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12 December 2020

Polio immunization: benefits and risks

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12 December 2020

Protection against Mycoplasma pulmonis infection by genetic vaccination

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12 December 2020

HLA DR4w4-binding motifs illustrate the biochemical basis of degeneracy and specificity in peptide-DR interactions

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12 December 2020

Lymphocyte responses and cytokines

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12 December 2020

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

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12 December 2020

Induction of humoral and cellular immune responses to the human immunodeficiency type 1 virus in nonhuman primates by in vivo DNA inoculation

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12 December 2020

Influenza subunit vaccine: antibody responses to one and two doses of vaccine and length of response, with particular reference to the elderly

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12 December 2020

Nucleic acid vaccines.

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12 December 2020

Vaccines containing purified GM2 ganglioside elicit GM2 antibodies in melanoma patients

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12 December 2020

Teaching the immune system to fight cancer.

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12 December 2020

Degradation rates of oral resorbable implants (polylactates and polyglycolates): rate modification with changes in PLA/PGA copolymer ratios

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12 December 2020

Cancer immunology: the search for specificity--G. H. A. Clowes Memorial lecture

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12 December 2020

The development of stable protein formulations: a close look at protein aggregation, deamidation, and oxidation.

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12 December 2020

Homology of proteasome subunits to a major histocompatibility complex-linked LMP gene

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12 December 2020

Towards a DNA vaccine against tuberculosis.

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12 December 2020

Effect of dose and immunization schedule on immune response of baboons to recombinant glycoprotein 120 of HIV-1.

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12 December 2020

Vaccine technologies: view to the future

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12 December 2020

Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer

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12 December 2020

Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad

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12 December 2020

The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route

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12 December 2020

Prolongation of survival in metastatic melanoma after active specific immunotherapy with a new polyvalent melanoma vaccine.

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12 December 2020

DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations

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12 December 2020

Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb molecule

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12 December 2020

Liposome mediated gene transfer

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12 December 2020

Liposome-encapsulated antigens are processed in lysosomes, recycled, and presented to T cells

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12 December 2020

Molecular and cellular aspects of immunologic tolerance

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12 December 2020

Biodegradable microparticles as controlled release antigen delivery systems.

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12 December 2020

Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen.

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12 December 2020

Comparative pathology of recombinant murine interferon-gamma in mice and recombinant human interferon-gamma in cynomolgus monkeys.

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12 December 2020

Prognostic indicators in node-negative early stage breast cancer

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12 December 2020

Immunological and formulation design considerations for subunit vaccines

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12 December 2020

Type 2 cytokines and negative immune regulation in human infections

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12 December 2020

[Genetic immunization--"the biological equivalent of cold fusion"?]

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12 December 2020

DNA immunization confers protection against lethal lymphocytic choriomeningitis virus infection.

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12 December 2020

A comparison of commercially available adjuvants for use in research

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12 December 2020

Protection of MN-rgp120-immunized chimpanzees from heterologous infection with a primary isolate of human immunodeficiency virus type 1.

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12 December 2020

Pharmacological enhancement of in vivo foreign gene expression in muscle

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12 December 2020

Antigen processing by endosomal proteases determines which sites of sperm-whale myoglobin are eventually recognized by T cells

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12 December 2020

Biodegradable microspheres as a vaccine delivery system

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12 December 2020

Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells

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12 December 2020

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12 December 2020

Immunity to intracellular bacteria

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12 December 2020

Measuring vaccine efficacy from epidemics of acute infectious agents

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12 December 2020

Cellular peptide composition governed by major histocompatibility complex class I molecules.

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12 December 2020

Neopterin as a marker for activated cell-mediated immunity: application in malignant disease

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12 December 2020

DNA vaccination for cancer treatment.

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12 December 2020

Human B-cell immune response to the polymorphic epithelial mucin.

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12 December 2020

Immune responses of mice and human breast cancer patients following immunization with synthetic sialyl-Tn conjugated to KLH plus detox adjuvant

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12 December 2020

Protective CTL-dependent immunity and enhanced immunopathology in mice immunized by particle bombardment with DNA encoding an internal virion protein

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12 December 2020

Attenuated Shigella as a DNA delivery vehicle for DNA-mediated immunization

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12 December 2020

Development of a single-shot subunit vaccine for HIV-1. 5. programmable in vivo autoboost and long lasting neutralizing response

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12 December 2020

The relative affinity of antibodies synthesized in the secondary response

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12 December 2020

Structural and serological similarity of MHC-linked LMP and proteasome (multicatalytic proteinase) complexes

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12 December 2020

Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex

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12 December 2020

Water-soluble phosphazene polymers for parenteral and mucosal vaccine delivery

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12 December 2020

Antibodies to Schistosoma japonicum (Asian bloodfluke) paramyosin induced by nucleic acid vaccination

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12 December 2020

High-level expression of the measles virus nucleocapsid protein by using a replication-deficient adenovirus vector: induction of an MHC-1-restricted CTL response and protection in a murine model

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12 December 2020

Evidence that treatment with vaccinia melanoma cell lysates (VMCL) may improve survival of patients with stage II melanoma. Treatment of stage II melanoma with viral lysates

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12 December 2020

Transport protein genes in the murine MHC: possible implications for antigen processing

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12 December 2020

Protection of ferrets against influenza challenge with a DNA vaccine to the haemagglutinin

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12 December 2020

I-Ad-binding peptides derived from unrelated protein antigens share a common structural motif

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12 December 2020

Regulation of MHC class I transport by the molecular chaperone, calnexin (p88, IP90).

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12 December 2020

Development of a single-shot subunit vaccine for HIV-1.

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12 December 2020

Gene gun transfection of animal cells and genetic immunization

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12 December 2020

The generation of immunogenic peptides can be selectively increased or decreased by proteolytic enzyme inhibitors

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12 December 2020

Proteolysis, proteasomes and antigen presentation

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12 December 2020

Gene transfer in regenerating muscle

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12 December 2020

Regulatory considerations for nucleic acid vaccines

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12 December 2020

Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments

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12 December 2020

Safety considerations for nucleic acid vaccines

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12 December 2020

Duration of antibody response after meningococcal polysaccharide vaccination in US Air Force personnel

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12 December 2020

Phenotypic and functional characterization of T cell lines specific for individual respiratory syncytial virus proteins

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12 December 2020

Examination of parameters affecting the elicitation of humoral immune responses by particle bombardment-mediated genetic immunization

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12 December 2020

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

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12 December 2020

A 9-year follow-up study of the immunogenicity and long-term efficacy of plasma-derived hepatitis B vaccine in high-risk Chinese neonates

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12 December 2020

Induction of long-term immunity to paralytic poliomyelitis by use of non-infectious vaccine

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12 December 2020

Cellular immunity to intracellular bacteria

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12 December 2020

A qualitative progression in HIV type 1 glycoprotein 120-specific cytotoxic cellular and humoral immune responses in mice receiving a DNA-based glycoprotein 120 vaccine

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12 December 2020

Utilization of homologous proteins to evaluate the safety of recombinant human proteins--case study: recombinant human interferon-gamma (rhIFN-gamma)

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12 December 2020

Design and production of single-immunization vaccines using polylactide polyglycolide microsphere systems

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12 December 2020

Malnutrition and overcrowding/intensive exposure in severe measles infection: review of community studies

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12 December 2020

Participation of a novel 88-kD protein in the biogenesis of murine class I histocompatibility molecules

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12 December 2020

Impaired response to recombinant hepatitis B vaccine in HIV-infected persons

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12 December 2020

A unique antigenic epitope of human melanoma is carried on the common melanoma glycoprotein gp95/p97

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12 December 2020

Duration and efficacy of immune response to hepatitis B vaccine in high-risk Chinese adolescents

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12 December 2020

Identifiers

DOI

10.1023/A:1016064504346

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29 September 2017

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PubMed ID

8987071