(Q41326897)

29 September 2017

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title

Immune deviation--the third dimension of nondeletional T cell tolerance (English)

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29 September 2017

Röcken M

1

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29 September 2017

Shevach EM

series ordinal

2

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29 September 2017

publication date

1 February 1996

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29 September 2017

published in

Immunological Reviews

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29 September 2017

volume

149

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29 September 2017

page(s)

175-194

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Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice

29 September 2017

cites work

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Multiple levels of peripheral tolerance

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Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma

21 January 2018

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Characterization of antigen-specific CD4+ effector T cells in vivo: immunization results in a transient population of MEL-14-, CD45RB- helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon gamma

21 January 2018

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In vivo role of interleukin 4 in T cell tolerance induced by aqueous protein antigen

21 January 2018

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Resting and activated T cells display different requirements for CD8 molecules

21 January 2018

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Relationships among antigen presentation, cytokines, immune deviation, and autoimmune disease

21 January 2018

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Production of autoreactive I region-restricted T cell hybridomas

21 January 2018

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TH2 cells in systemic autoimmunity: insights from allogeneic diseases and chemically-induced autoimmunity

21 January 2018

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CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

21 January 2018

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Induction of peripheral tolerance to class I major histocompatibility complex (MHC) alloantigens in adult mice: transfused class I MHC-incompatible splenocytes veto clonal responses of antigen-reactive Lyt-2+ T cells

21 January 2018

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Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets

21 January 2018

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Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo

21 January 2018

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Selective anergy of V beta 8+,CD4+ T cells in Staphylococcus enterotoxin B-primed mice

21 January 2018

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Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

21 January 2018

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B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

21 January 2018

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Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin

21 January 2018

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Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells

21 January 2018

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Acute lethal graft-versus-host reaction induced by major histocompatibility complex class II-reactive T helper cell clones

21 January 2018

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Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

21 January 2018

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Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells

21 January 2018

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Tolerance to peripheral antigens must involvenon-deletional mechanisms

21 January 2018

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T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens

21 January 2018

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Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

21 January 2018

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Immune response to chemically modified flagellin. 3. Enhanced cell-mediated immunity during high and low zone antibody tolerance to flagellin

21 January 2018

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Lymphocyte responses and cytokines

21 January 2018

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Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo

21 January 2018

1 reference

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Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity.

21 January 2018

1 reference

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Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease

21 January 2018

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Clonal anergy induced in mature V beta 6+ T lymphocytes on immunizing Mls-1b mice with Mls-1a expressing cells

21 January 2018

1 reference

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In vivo induction of anergy in peripheral V beta 8+ T cells by staphylococcal enterotoxin B.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Induction of T helper cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Infection breaks T-cell tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Do parasitic infections break T-cell tolerance and trigger autoimmune disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Antigen-specific activation, tolerization, and reactivation of the interleukin 4 pathway in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Prevention of experimental allergic encephalomyelitis in rats by targeting autoantigen to B cells: evidence that the protective mechanism depends on changes in the cytokine response and migratory properties of the autoantigen-specific T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Interleukin 4 production by CD4+ T cells from allergic individuals is modulated by antigen concentration and antigen-presenting cell type

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Distinct fates of self-specific T cells developing in irradiation bone marrow chimeras: clonal deletion, clonal anergy, or in vitro responsiveness to self-Mls-1a controlled by hemopoietic cells in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Activation of CD4+ T cells in the presence of a nondepleting monoclonal antibody to CD4 induces a Th2-type response in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Generation and in vivo persistence of polarized Th1 and Th2 memory cells

21 January 2018

1 reference

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Amino acid residues that flank core peptide epitopes and the extracellular domains of CD4 modulate differential signaling through the T cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Autoimmune diabetes as a consequence of locally produced interleukin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Antigen presenting function of class II MHC expressing pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Lower receptor avidity required for thymic clonal deletion than for effector T-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

On the control between cell-mediated, IgM and IgG immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

The relationship of IL-4- and IFNγ-producing T cells studied by lineage ablation of IL-4-producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Immunological function of a defined T-cell population tolerized to low-affinity self antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4,

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00904.X

10.1111/J.1600-065X.1996.TB00904.X

21 January 2018

Identifiers

DOI

1 reference

29 September 2017

1 reference