(Q41331950)

29 September 2017

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title

The non-antiemetic uses of serotonin 5-HT3 receptor antagonists. Clinical pharmacology and therapeutic applications (English)

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29 September 2017

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Greenshaw AJ

1

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29 September 2017

Silverstone PH

series ordinal

2

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29 September 2017

publication date

1 January 1997

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29 September 2017

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29 September 2017

volume

53

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29 September 2017

issue

1

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29 September 2017

page(s)

20-39

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Effects of d-fenfluramine, MK-212, and ondansetron on saline drinking in two-choice tests in the rehydrating rat.

29 September 2017

cites work

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12 December 2020

5-Hydroxytryptamine3 receptors sited on cholinergic axon terminals of human cerebral cortex mediate inhibition of acetylcholine release

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12 December 2020

New anxiolytics in development.

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12 December 2020

Randomized, placebo-controlled evaluation of prochlorperazine versus metoclopramide for emergency department treatment of migraine headache

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12 December 2020

Effects of antidepressants on the inward current mediated by 5‐HT3 receptors in rat nodose ganglion neurones

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12 December 2020

5-HT3 receptor antagonists. 3. Quinoline derivatives which may be effective in the therapy of irritable bowel syndrome

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12 December 2020

Effects of 5-HT3 agonists on reproductive behaviors in rats

1 reference

12 December 2020

Effects of 5-hydroxytryptamine3 antagonist, ondansetron, on cigarette smoking, smoke exposure, and mood in humans.

1 reference

12 December 2020

Efficacy of ICS 205-930, a novel 5-hydroxytryptamine3 (5-HT3) receptor antagonist, in the prevention of migraine attacks. A complex answer to a simple question. ICS 205-930 Migraine Study Group.

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12 December 2020

Parameters of self-administration of cocaine in rats under a progressive-ratio schedule.

1 reference

12 December 2020

Effects of 5HT3 receptor antagonism by tropisetron on the sleep EEG and on nocturnal hormone secretion

1 reference

12 December 2020

Reversal of neuroleptic-induced catalepsy by novel aryl-piperazine anxiolytic drugs

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12 December 2020

Handling history of rats modifies behavioural effects of drugs in the elevated plus-maze test of anxiety

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12 December 2020

5-HT3 receptors mediate inhibition of acetylcholine release in cortical tissue

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12 December 2020

Anorectic response to amino acid imbalance: a selective serotonin3 effect?

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12 December 2020

Effects of 5-HT3 receptor antagonism on hippocampal theta rhythm, memory, and LTP induction in the freely moving rat.

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12 December 2020

Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species

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12 December 2020

Comparative involvement of 5-HT1, 5-HT2 and 5-HT3 receptors in stress-induced colonic motor alterations in rats

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12 December 2020

The effects of tacrine and zacopride on the performance of adult rats in the working memory task.

1 reference

12 December 2020

GR38032F, a serotonin 5-HT3 antagonist, fails to alter cocaine self-administration in rats.

1 reference

12 December 2020

5HT3 receptor antagonists block morphine- and nicotine- but not amphetamine-induced reward.

1 reference

12 December 2020

Analgesic action of metoclopramide in prosthetic hip surgery.

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12 December 2020

Identification and distribution of 5-HT3 receptors in rat brain using radioligand binding

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12 December 2020

Effects of 5-HT3 receptor antagonists on neuroleptic-induced catalepsy in mice

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12 December 2020

Reduction of rectal sensitivity and post-prandial motility by granisetron, a 5 HT3-receptor antagonist, in patients with irritable bowel syndrome

1 reference

12 December 2020

Chronic BRL 43694, a selective 5-HT3 receptor antagonist, fails to alter the number of spontaneously active midbrain dopamine neurons

1 reference

12 December 2020

Ondansetron fails to attenuate a scopolamine-induced deficit in a Stone maze task.

1 reference

12 December 2020

Molecular biology of 5-HT receptors

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12 December 2020

Differential effects of ondansetron, haloperidol and clozapine on electrical self-stimulation of the ventral tegmental area

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12 December 2020

Effect of a 5HT3-antagonist (ondansetron) on rectal sensitivity and compliance in health and the irritable bowel syndrome.

1 reference

12 December 2020

[Central serotonin receptors. Principal fundamental and functional aspects. Therapeutic applications]

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12 December 2020

Effects of 8-OH-DPAT, buspirone and ICS 205-930 on feeding in a novel environment: comparisons with chlordiazepoxide and FG 7142.

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12 December 2020

5-HT3 agonist-induced dopamine overflow during withdrawal from continuous or intermittent cocaine administration

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12 December 2020

CCK in animal and human research on anxiety

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12 December 2020

Non-reversal of scopolamine- or age-related EEG changes by ondansetron, methysergide or alaproclate

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12 December 2020

Localization of 5-HT3 receptors in the rat spinal cord: immunohistochemistry and in situ hybridization

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12 December 2020

Spinal 5-HT3 receptor-mediated antinociception: possible release of GABA.

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12 December 2020

Evaluation of the 5HT3 antagonist ondansetron (O) for cocaine (C)-like activity and abuse potential

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12 December 2020

Serotonin receptors and therapeutics.

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12 December 2020

Ondansetron improves cognitive performance in the Morris water maze spatial navigation task.

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12 December 2020

Intrathecal 5-methoxy-N,N-dimethyltryptamine in mice modulates 5-HT1 and 5-HT3 receptors

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12 December 2020

Serotonin3 receptor antagonists block anorectic responses to amino acid imbalance

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12 December 2020

Ethanol- and diazepam-withdrawal hyperlocomotion is not due to 5-HT3 receptor stimulation.

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12 December 2020

Pharmacological mechanisms and animal models of cognition.

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12 December 2020

5-HT3 receptor binding sites are on capsaicin-sensitive fibres in the rat spinal cord.

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12 December 2020

Electrophysiological, biochemical and behavioral evidence for 5-HT2 and 5-HT3 mediated control of dopaminergic function

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12 December 2020

Effects of chronic administration of ondansetron (GR38032F), a selective 5-HT3 receptor antagonist, on monoamine metabolism in mesolimbic and nigrostriatal dopaminergic neurons and on striatal D2-receptor binding

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12 December 2020

5-HT3 receptors modulate spinal nociceptive reflexes

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12 December 2020

Alcohol drinking in rats treated with 5,7-dihydroxytryptamine: effect of 8-OH-DPAT and tropisetron (ICS 205-930).

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12 December 2020

Litoxetine: a selective 5-HT uptake inhibitor with concomitant 5-HT3 receptor antagonist and antiemetic properties

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12 December 2020

Zatosetron, a 5-HT3 receptor antagonist in a multicenter trial for acute migraine

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12 December 2020

Effect of 5-HT3 receptor antagonists on the discriminative stimulus properties of morphine in rats.

1 reference

12 December 2020

Effect of the 5-hydroxytryptamine3 receptor antagonist itasetron (DAU 6215) on (+)-N-allylnormetazocine-induced dopamine release in the nucleus accumbens and in the corpus striatum of the rat: an in vivo microdialysis study

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12 December 2020

The effect of ondansetron on cognitive performance in the marmoset

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12 December 2020

Serotonergic facilitation of acetylcholine release in vivo from rat dorsal hippocampus via serotonin 5-HT3 receptors.

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12 December 2020

Evidence that the atypical 5-HT3 receptor ligand, [3H]-BRL46470, labels additional 5-HT3 binding sites compared to [3H]-granisetron

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12 December 2020

1-(m-chlorophenyl)-biguanide, a potent high affinity 5-HT3 receptor agonist.

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12 December 2020

5-HT3 receptor ligands lack modulatory influence on acetylcholine release in rat entorhinal cortex

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12 December 2020

SR 57227A: a potent and selective agonist at central and peripheral 5-HT3 receptors in vitro and in vivo.

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12 December 2020

Identification and distribution of 5-HT3 recognition sites in the rat gastrointestinal tract

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12 December 2020

5-HT3 receptor agonist induced carrier-mediated release of dopamine in rat striatum in vivo

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12 December 2020

MDL72222, a serotonin 5-HT3 receptor antagonist, blocks MDMA's ability to establish a conditioned place preference.

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12 December 2020

Astra Award Lecture. The psychopharmacology of 5-HT3 receptors

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12 December 2020

5-HT3 receptor antagonists attenuate cocaine-induced locomotion in mice.

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12 December 2020

Ondansetron, a selective 5-HT3 receptor antagonist, reduces palatable food consumption in the nondeprived rat.

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12 December 2020

5-HT3 receptor antagonists inhibit morphine-induced stimulation of mesolimbic dopamine release and function in the rat.

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12 December 2020

Metoclopramide in migrane treatment

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12 December 2020

Involvement of 5-HT3 receptor in the pressure-induced increase in striatal and accumbens dopamine release and the occurrence of behavioral disorders in free-moving rats

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12 December 2020

New animal models of anxiety

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12 December 2020

Ondansetron in treatment of schizophrenia

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12 December 2020

Cholecystokinin release mediated by 5-HT3 receptors in rat cerebral cortex and nucleus accumbens

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12 December 2020

Antagonists at the serotonin-3 receptor can reduce the fear-potentiated startle response in the rat: evidence for different types of anxiolytic activity?

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12 December 2020

Normal densities of 5-HT3 receptor recognition sites in Alzheimer's disease.

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12 December 2020

5HT3 receptor antagonists do not block nicotine induced hyperactivity in rats

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12 December 2020

A randomized double-blind placebo-controlled study of tropisetron in the treatment of outpatients with generalized anxiety disorder

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12 December 2020

1 reference

12 December 2020

Antidepressant-like effects of SR 57227A, a 5-HT3 receptor agonist, in rodents

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12 December 2020

The selective 5-HT3 receptor antagonist, ondansetron, augments the anorectic effect of d-amphetamine in nondeprived rats

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12 December 2020

Central action of 5-HT3 receptor ligands in the regulation of sleep-wakefulness and raphe neuronal activity in the rat

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12 December 2020

Investigation of the role of 5-HT3 and 5-HT4 receptors in ascending and descending reflexes to the circular muscle of guinea-pig small intestine

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12 December 2020

The selective 5-HT3 receptor antagonist, WAY100289, enhances spatial memory in rats with ibotenate lesions of the forebrain cholinergic projection system.

1 reference

12 December 2020

The role of 5-HT3 receptors in drug dependence

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12 December 2020

Effects of DAU 6215, a novel 5-hydroxytryptamine3 (5-HT3) antagonist on electrophysiological properties of the rat hippocampus

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12 December 2020

Reduced levels of 5-HT3 receptor recognition sites in the putamen of patients with Huntington's disease

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12 December 2020

5-HT3 receptors and the therapeutic potential of 5-HT3 receptor antagonists

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12 December 2020

Local 5HT3 receptors mediate fluoxetine but not desipramine-induced increase of extracellular dopamine in the prefrontal cortex

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12 December 2020

Effect of drugs influencing 5-HT function on ethanol drinking and feeding behaviour in rats: studies using a drinkometer system.

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12 December 2020

The 5-HT3 antagonist MDL-72222 exacerbates ethanol withdrawal seizures in mice

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12 December 2020

Zacopride in schizophrenia: a single-blind serotonin type 3 antagonist trial

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12 December 2020

Functional characterization of a 5-HT3 receptor which modulates the release of 5-HT in the guinea-pig brain

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12 December 2020

Effects on migraine headache of MDL 72,222, an antagonist at neuronal 5-HT receptors. Double-blind, placebo-controlled study

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12 December 2020

Aggression, anxiety and vocalizations in animals: GABAA and 5-HT anxiolytics.

1 reference

12 December 2020

Effect of the 5-HT3 receptor antagonist, GR38032F, on responses to injection of a neurokinin agonist into the ventral tegmental area of the rat brain

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12 December 2020

The 5-HT3 receptor antagonist zatosetron decreases the number of spontaneously active A10 dopamine neurons

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12 December 2020

Differentiation Alters the Expression of the Two Splice Variants of the Serotonin 5‐HT3 Receptor‐A mRNA in NG108‐15 Cells

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12 December 2020

A multicentre double-blind comparative trial of fluvoxamine versus lorazepam in mixed anxiety and depression treated in general practice

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12 December 2020

BRL 46470A: a highly potent, selective and long acting 5-HT3 receptor antagonist with anxiolytic-like properties

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12 December 2020

DAU 6215, a novel 5-HT3-receptor antagonist, selectively antagonizes scopolamine-induced deficit in a passive-avoidance task, but not scopolamine-induced hypermotility in rats

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12 December 2020

The effect of 5-HT3 receptor antagonists on the morphine-induced excitation of A10 dopamine cells: electrophysiological studies

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12 December 2020

Blockade of acquisition of drug-conditioned place aversion by 5HT3 antagonists.

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12 December 2020

Effects of the 5-HT3 antagonist GR38032F (ondansetron) on benzodiazepine withdrawal in rats

1 reference

12 December 2020

First Clinical Study of the Selective 5-HT3 Antagonist, Granisetron (BRL 43694), in the Acute Treatment of Migraine Headache

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12 December 2020

Effects of acute administration of the 5-HT3 receptor antagonist, BRL 46470A, on the behaviour of mice in a two compartment light-dark box and during social interactions in their home cage and an unfamiliar neutral cage

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12 December 2020

Interaction between enantiomers of mianserin and ORG3770 at 5-HT3 receptors in cultured mouse neuroblastoma cells

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12 December 2020

5-HT and alcohol abuse

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12 December 2020

Psychosis in advanced Parkinson's disease: treatment with ondansetron, a 5-HT3 receptor antagonist

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12 December 2020

Activation of 5-HT3 receptors enhances the electrically evoked release of [3H]noradrenaline in rat brain limbic structures

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12 December 2020

Effect of the 5-HT3 receptor antagonist ondansetron on hypothalamic self-stimulation in rats and its interaction with the CCK analogue caerulein

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12 December 2020

5-HT3 receptors are membrane ion channels

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12 December 2020

The 5-HT3 receptor channel

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12 December 2020

Vagal afferent-mediated inhibition of a nociceptive reflex by i.v. serotonin in the rat. II. Role of 5-HT receptor subtypes

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12 December 2020

Effect of acute and chronic MDL 73,147EF, a 5-HT3 receptor antagonist, on A9 and A10 dopamine neurons

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12 December 2020

Effect of DAU 6215, a novel 5-HT3 receptor antagonist, on scopolamine-induced amnesia in the rat in a spatial learning task

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12 December 2020

Influence of 5-HT3 receptor antagonists in visceromotor and nociceptive responses to rectal distension before and during experimental colitis in rats

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12 December 2020

Quantitative autoradiographic mapping of 5-HT3 receptors in the rat CNS using [125I]iodo-zacopride and [3H]zacopride as radioligands

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12 December 2020

8-OH-DPAT specifically enhances feeding behaviour in mice: evidence from behavioural competition

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12 December 2020

The abilities of 5-HT3 receptor antagonist ICS 205-930 to inhibit alcohol preference and withdrawal seizures in rats

1 reference

12 December 2020

Lack of effects of 5HT3 receptor antagonists in the social interaction and elevated plus-maze tests of anxiety in the rat.

1 reference

12 December 2020

1 reference

12 December 2020

The interaction of antidepressant drugs with central and peripheral (enteric) 5-HT3 and 5-HT4 receptors

1 reference

12 December 2020

Behavioural studies on WAY100289, a novel 5-HT3 receptor antagonist, in two animal models of anxiety

1 reference

12 December 2020

Effects of serotonin receptor antagonists on PAG stimulation induced aversion: different contributions of 5HT1, 5HT2 and 5HT3 receptors

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12 December 2020

The effect of drugs interacting with serotonergic 5HT3 and 5HT4 receptors on morphine place conditioning

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12 December 2020

Serotonin, schizophrenia and antipsychotic drug action

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12 December 2020

Enhancement of memory retrieval and attenuation of scopolamine-induced amnesia following administration of 5-HT3 antagonist ICS 205-930

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12 December 2020

Spinal supersensitivity to 5-HT1, 5-HT2 and 5-HT3 receptor agonists following 5,7-dihydroxytryptamine

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12 December 2020

The 5-HT3 antagonist, BRL 46470 does not attenuate m-chlorophenylpiperazine (mCPP)-induced changes in human volunteers.

1 reference

12 December 2020

Effect of the 5-HT3 receptor antagonists, MDL72222 and ondansetron on morphine place conditioning

1 reference

12 December 2020

An overview of fluoxetine, a new serotonin-specific antidepressant

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12 December 2020

Effects of the 5-HT3 receptor antagonist, GR38032F, on raised dopaminergic activity in the mesolimbic system of the rat and marmoset brain

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12 December 2020

The effect of 5-HT3 receptor antagonists on the writhing response in mice

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12 December 2020

Serotonin 5-HT3 receptors in schizophrenia: a postmortem study of the amygdala

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12 December 2020

Ondansetron, a 5-HT3 receptor antagonist, partially attenuates the effects of amphetamine: a pilot study in healthy volunteers

1 reference

12 December 2020

A double-blind comparison of granisetron and placebo for the treatment of acute migraine in the emergency department

1 reference

12 December 2020

Serotonin 5-HT3 antagonists do not alter the discriminative stimulus properties of cocaine.

1 reference

12 December 2020

Influence of 5-HT3 receptor antagonists and the indirect 5-HT agonist, dexfenfluramine, on heroin self-administration in rats.

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12 December 2020

5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: More than 30 years of research

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12 December 2020

Effects of ondansetron pretreatment on acute responses to ethanol in social drinkers.

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12 December 2020

Constipation evoked by 5-HT3-receptor antagonism: evidence for heterogeneous efficacy among different antagonists in guinea-pigs.

1 reference

12 December 2020

Failure of ondansetron to block the discriminative or reinforcing stimulus effects of cocaine in the rat.

1 reference

12 December 2020

A placebo-controlled inpatient comparison of fluvoxamine maleate and imipramine in major depression.

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12 December 2020

Ondansetron and opiate craving. A novel pharmacological approach to addiction.

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12 December 2020

Evaluation of anxiolytic action of ondansetron in rats during withdrawal from chronic chlordiazepoxide

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12 December 2020

Naloxone and serotonin receptor subtype antagonists: interactive effects upon deprivation-induced intake

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12 December 2020

Clinical efficacy of the 5-HT3 antagonist ondansetron in alcohol abuse and dependence.

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12 December 2020

Selective 5-hydroxytryptamine type 3 receptor antagonism with ondansetron as treatment for diarrhea-predominant irritable bowel syndrome: a pilot study

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12 December 2020

Allosteric interactions among agonists and antagonists at 5-hydroxytryptamine3 receptors

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12 December 2020

Localization of 5-HT3 receptors in the rat brain using [3H]LY278584.

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12 December 2020

5-HT receptor sub-types: aspects of their regulation and function

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12 December 2020

Effects of the 5-HT3 antagonist ondansetron on benzodiazepine-induced operant behavioural dependence in rats.

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12 December 2020

Differences between 5-HT3 receptor antagonists in modulation of visceral hypersensitivity

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12 December 2020

Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel

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12 December 2020

5-HT3 receptors control dopamine release in the nucleus accumbens of freely moving rats.

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12 December 2020

[3H]ICS 205-930 labels 5-HT3 recognition sites in membranes of cat and rabbit vagus nerve and superior cervical ganglion

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12 December 2020

Interactions between 5-HT3 receptors and cerebral dopamine function: implications for the treatment of schizophrenia and psychoactive substance abuse

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12 December 2020

Evidence that the amygdala is involved in the disinhibitory effects of 5-HT3 receptor antagonists

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12 December 2020

Behavioural pharmacology of 5-HT3 receptor antagonists: a critical update on therapeutic potential

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12 December 2020

The effect of a 5-HT3 receptor antagonist, ondansetron, on brain stimulation reward, and its interaction with direct and indirect stimulants of central dopaminergic transmission

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12 December 2020

Effect of serotonergic agonists in the nucleus accumbens on d-amphetamine-stimulated locomotion

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12 December 2020

Serotonin 5-HT3 antagonists fail to affect ethanol self-administration of rats.

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12 December 2020

Serotonin3 antagonists block aversion to saccharin in an amino acid-imbalanced diet.

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12 December 2020

5-HT3 receptors: pharmacologic and therapeutic aspects

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12 December 2020

Lack of effects of 5-HT3 antagonists on normal and morphine-attenuated sexual behaviours in female and male rats

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12 December 2020

MDL 72222, ketanserin, and methysergide pretreatments fail to alter breaking points on a progressive ratio schedule reinforced by intravenous cocaine.

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12 December 2020

Inhibition of a 5-HT3 receptor-mediated current by the selective serotonin uptake inhibitor, fluoxetine

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12 December 2020

Comparison of the 5-hydroxytryptamine3 (serotonin) antagonist ondansetron (GR 38032F) with high-dose metoclopramide in the control of cisplatin-induced emesis.

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12 December 2020

Nicotine self-administration and locomotor activity are not modified by the 5-HT3 antagonists ICS 205-930 and MDL 72222.

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12 December 2020

Metoclopramide: an analgesic adjunct to patient-controlled analgesia

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12 December 2020

5-HT3 antagonists reduce morphine self-administration in rats

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12 December 2020

The effect of 5-HT3 receptor antagonists on the discriminative stimulus effects of amphetamine

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12 December 2020

10.2165/00003495-199753010-00003

Identifiers

DOI

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Dimensions Publication ID

29 September 2017

1042746987

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