(Q41332828)

29 September 2017

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title

Hepatitis C virus: molecular biology and genetic variability (English)

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29 September 2017

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C Bréchot

1

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29 September 2017

1 December 1996

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Digestive Diseases and Sciences

29 September 2017

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29 September 2017

41

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29 September 2017

6S-21S

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29 September 2017

12 Suppl

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https://scigraph.springernature.com/pub.10.1007/bf02087872

29 September 2017

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https://api.crossref.org/works/10.1007%2FBF02087872

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Non-A, non-B post-transfusion hepatitis. Looking back in the second decade

21 January 2018

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Hepatitis C Virus Not Found in Fulminant Non-A, Non-B Hepatitis

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF02087872

Hepatitis C virus is detected in a monocyte/macrophage subpopulation of peripheral blood mononuclear cells of infected patients

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF02087872

Hepatitis C virus and autoimmunity: fortuitous association or reality?

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF02087872

Frequent reinfection and reactivation of hepatitis C virus genotypes in multitransfused hemophiliacs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02087872

Mixed infections of hepatitis C virus as a factor in acute exacerbations of chronic type C hepatitis

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF02087872

Extrahepatic immunologic manifestations in chronic hepatitis C and hepatitis C virus serotypes

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF02087872

Eradication of hepatitis C virus RNA after alpha-interferon therapy

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF02087872

Superinfection of heterologous hepatitis C virus in a patient with chronic type C hepatitis

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FBF02087872

21 January 2018

12 December 2020

Differential distribution of hepatitis C virus genotypes in patients with and without liver function abnormalities

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12 December 2020

Detection of hepatitis C virus RNA in peripheral blood mononuclear cells of infected patients by in situ hybridization.

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12 December 2020

Genotypic analysis of hepatitis C virus in American patients

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12 December 2020

Replication of hepatitis C virus in peripheral blood mononuclear cells. Effect of alpha-interferon therapy

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12 December 2020

Mapping of serotype-specific, immunodominant epitopes in the NS-4 region of hepatitis C virus (HCV): use of type-specific peptides to serologically differentiate infections with HCV types 1, 2, and 3

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12 December 2020

Extraordinarily low density of hepatitis C virus estimated by sucrose density gradient centrifugation and the polymerase chain reaction

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12 December 2020

Detection of hepatitis C virus by polymerase chain reaction and response to interferon-alpha therapy: relationship to genotypes of hepatitis C virus

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12 December 2020

Susceptibility of human liver cell cultures to hepatitis C virus infection

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12 December 2020

Influence of viral quasispecies on effectiveness of interferon therapy in chronic hepatitis C patients

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12 December 2020

Clinical outcomes after transfusion-associated hepatitis C.

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12 December 2020

Equilibrium centrifugation studies of hepatitis C virus: evidence for circulating immune complexes

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12 December 2020

Selective accumulation of the X transcript of hepatitis B virus in patients negative for hepatitis B surface antigen with hepatocellular carcinoma

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12 December 2020

Internal ribosome entry site within hepatitis C virus RNA

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12 December 2020

Genetic alterations of the putative envelope proteins encoding region of the hepatitis C virus in the progression to relapsed phase from acute hepatitis: humoral immune response to hypervariable region 1.

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12 December 2020

Biosynthesis and biochemical properties of the hepatitis C virus core protein

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12 December 2020

Reinfection of liver graft by hepatitis C virus after liver transplantation

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12 December 2020

Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins

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12 December 2020

Preparation and characterization of RNA standards for use in quantitative branched DNA hybridization assays

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12 December 2020

Hepatitis C virus genotypes in France: comparison of clinical features of patients infected with HCV type I and type II.

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12 December 2020

Fluctuation of hepatitis C virus quasispecies in persistent infection and interferon treatment revealed by single-strand conformation polymorphism analysis

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12 December 2020

Hepatitis C virus in multiple episodes of acute hepatitis in polytransfused thalassaemic children

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12 December 2020

The physical state of the negative strand of hepatitis C virus RNA in serum of patients with chronic hepatitis C.

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12 December 2020

Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses

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12 December 2020

Detection of replicative intermediates of hepatitis C viral RNA in liver and serum of patients with chronic hepatitis C

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12 December 2020

Characterization of the 5' noncoding and structural region of the hepatitis C virus genome from patients with non-A, non-B hepatitis responding differently to interferon treatment

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12 December 2020

Hepatitis C virus nonstructural protein NS3 transforms NIH 3T3 cells

1 reference

12 December 2020

Analysis of hepatitis C virus genotypes by a line probe assay and correlation with antibody profiles

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12 December 2020

Degree of diversity of hepatitis C virus quasispecies and progression of liver disease

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12 December 2020

Hepatitis C virus genotypes are not responsible for development of serious liver disease

1 reference

12 December 2020

Survey of major genotypes and subtypes of hepatitis C virus using RFLP of sequences amplified from the 5' non-coding region

1 reference

12 December 2020

Interferon therapy in chronic hepatitis C virus: evidence of different outcome with respect to different viral strains.

1 reference

12 December 2020

Expression and identification of hepatitis C virus polyprotein cleavage products

1 reference

12 December 2020

Humoral immune response to hypervariable region 1 of the putative envelope glycoprotein (gp70) of hepatitis C virus

1 reference

12 December 2020

Hepatitis C virus (HCV) circulates as a population of different but closely related genomes: quasispecies nature of HCV genome distribution

1 reference

12 December 2020

Single-step nested polymerase chain reaction for detection of different genotypes of hepatitis C virus

1 reference

12 December 2020

Substrate determinants for cleavage in cis and in trans by the hepatitis C virus NS3 proteinase

1 reference

12 December 2020

Variability of hepatitis C virus

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12 December 2020

Antibodies in human sera specific to hypervariable region 1 of hepatitis C virus can block viral attachment

1 reference

12 December 2020

Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV

1 reference

12 December 2020

Establishment of a cell line constitutively expressing E2 glycoprotein of hepatitis C virus and humoral response of hepatitis C patients to the expressed protein

1 reference

12 December 2020

T-lymphocyte response to hepatitis C virus in different clinical courses of infection

1 reference

12 December 2020

Hepatitis C virus genotypes: an investigation of type-specific differences in geographic origin and disease

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12 December 2020

Hepatitis C virus (HCV) core serotypes in chronic HCV infection

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12 December 2020

Quantification of hepatitis C virus by competitive reverse transcription-polymerase chain reaction: increase of the virus in advanced liver disease

1 reference

12 December 2020

Infection of peripheral mononuclear blood cells by hepatitis C virus

1 reference

12 December 2020

Hepatitis C viral complexity detected by single-strand conformation polymorphism and response to interferon therapy

1 reference

12 December 2020

Hepatitis C virus RNA and hepatitis B virus DNA in serum and liver of patients with fulminant hepatitis.

1 reference

12 December 2020

Hepatitis C Virus in Fulminant Hepatic Failure

1 reference

12 December 2020

Specific detection of positive and negative stranded hepatitis C viral RNA using chemical RNA modification

1 reference

12 December 2020

Trans-suppression of gene expression by hepatitis C viral core protein

1 reference

12 December 2020

Modulation of the trans-suppression activity of hepatitis C virus core protein by phosphorylation

1 reference

12 December 2020

Vaccination of chimpanzees against infection by the hepatitis C virus

1 reference

12 December 2020

Hepatitis C viral quasispecies in hepatitis C virus carriers with normal liver enzymes and patients with type C chronic liver disease

1 reference

12 December 2020

Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus

1 reference

12 December 2020

Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing

1 reference

12 December 2020

Classifying hepatitis C virus genotypes

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12 December 2020

Analysis of hepatitis C virus genome in patients with autoimmune hepatitis type 2.

1 reference

12 December 2020

Molecular biology of the hepatitis C viruses: implications for diagnosis, development and control of viral disease

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12 December 2020

Variation of the hepatitis C virus 5' non-coding region: implications for secondary structure, virus detection and typing. The International HCV Collaborative Study Group.

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12 December 2020

Influence of the genotypes of hepatitis C virus on the severity of recurrent liver disease after liver transplantation

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12 December 2020

Geographical distribution of hepatitis C virus genotypes in blood donors: an international collaborative survey

1 reference

12 December 2020

Fulminant or subfulminant non-A, non-B viral hepatitis: the role of hepatitis C and E viruses

1 reference

12 December 2020

Evolution and selection of hepatitis C virus variants in patients with chronic hepatitis C.

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12 December 2020

Typing of hepatitis C virus genomes by restriction fragment length polymorphism

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12 December 2020

Hepatic and extrahepatic HCV RNA strands in chronic hepatitis C: different patterns of response to interferon treatment

1 reference

12 December 2020

Hepatitis C virus: from epidemiology and molecular virology to immunobiology

1 reference

12 December 2020

Secondary structure of the 5' nontranslated regions of hepatitis C virus and pestivirus genomic RNAs

1 reference

12 December 2020

Hepatitis C virus genetic variability: clinical implications

1 reference

12 December 2020

HCV-associated liver cancer without cirrhosis

1 reference

12 December 2020

Non-Hodgkin's lymphoma: possible role of hepatitis C virus

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12 December 2020

Significance of specific antibody assay for genotyping of hepatitis C virus

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12 December 2020

Long-term mortality after transfusion-associated non-A, non-B hepatitis. The National Heart, Lung, and Blood Institute Study Group

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12 December 2020

Hepatitis C virus genotype 4 is highly prevalent in central Africa (Gabon).

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12 December 2020

A role for hepatitis C virus infection in type II cryoglobulinemia

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12 December 2020

Randomized trial comparing three different regimens of alpha-2a-interferon in chronic hepatitis C. The TriVeneto Viral Hepatitis Group

1 reference

12 December 2020

Antigenicities of Group I and II hepatitis C virus polypeptides--molecular basis of diagnosis

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12 December 2020

Lack of detection of negative-strand hepatitis C virus RNA in peripheral blood mononuclear cells and other extrahepatic tissues by the highly strand-specific rTth reverse transcriptase PCR

1 reference

12 December 2020

Hepatitis C virus-RNAs in plasma and in peripheral blood mononuclear cells of hemophiliacs with chronic hepatitis C: evidence for viral replication in peripheral blood mononuclear cells

1 reference

12 December 2020

Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant

1 reference

12 December 2020

Prevalence of hepatitis C virus genotypes in Italy

1 reference

12 December 2020

Specific inhibition of hepatitis C virus expression by antisense oligodeoxynucleotides. In vitro model for selection of target sequence

1 reference

12 December 2020

Persistence of hepatitis B and hepatitis C viral genomes in primary liver cancers from HBsAg-negative patients: a study of a low-endemic area

1 reference

12 December 2020

Peripheral blood leukocytes serve as a possible extrahepatic site for hepatitis C virus replication

1 reference

12 December 2020

The Particle Size Of Hepatitis C Virus Estimated By Filtration Through Microporous Regenerated Cellulose Fibre

1 reference

12 December 2020

NS3-4A of hepatitis C virus is a chymotrypsin-like protease

1 reference

12 December 2020

Long-term follow-up of non-A, non-B (type C) post-transfusion hepatitis

1 reference

12 December 2020

Hepatitis C virus particle detected by immunoelectron microscopic study

1 reference

12 December 2020

Typing of hepatitis C virus isolates by DNA enzyme immunoassay

1 reference

12 December 2020

Transfection of a differentiated human hepatoma cell line (Huh7) with in vitro-transcribed hepatitis C virus (HCV) RNA and establishment of a long-term culture persistently infected with HCV

1 reference

12 December 2020

Hepatitis C virus NS3 serine proteinase: trans-cleavage requirements and processing kinetics

1 reference

12 December 2020

Comparative analysis of two assays for genotyping hepatitis C virus based on genotype-specific primers or probes

1 reference

12 December 2020

Recent advances in pestivirus research

1 reference

12 December 2020

Evidence for in vitro replication of hepatitis C virus genome in a human T-cell line

1 reference

12 December 2020

The changing relative prevalence of hepatitis C virus genotypes: evidence in hemodialyzed patients and kidney recipients

1 reference

12 December 2020

Expression and processing of putative nonstructural proteins of hepatitis C virus in insect cells using baculovirus vector

1 reference

12 December 2020

Hepatitis C serotype and response to interferon therapy.

1 reference

12 December 2020

Hepatitis C virus serotype II responds more favorably to interferon-alpha therapy

1 reference

12 December 2020

Hepatitis C viremia in chronic liver disease: relationship to interferon-alpha or corticosteroid treatment

1 reference

12 December 2020

Recurrent and acquired hepatitis C viral infection in liver transplant recipients

1 reference

12 December 2020

Ability of prolonged interferon treatment to suppress relapse after cessation of therapy in patients with chronic hepatitis C: a multicenter randomized controlled trial.

1 reference

12 December 2020

Association of hepatitis C virus in human sera with beta-lipoprotein

1 reference

12 December 2020

Hepatitis C virus variants from Vietnam are classifiable into the seventh, eighth, and ninth major genetic groups

1 reference

12 December 2020

Intracellular localization of full-length and truncated hepatitis C virus core protein expressed in mammalian cells.

1 reference

12 December 2020

Genetic drift in hypervariable region 1 of the viral genome in persistent hepatitis C virus infection

1 reference

12 December 2020

HCV genotypes in chronic hepatitis C and response to interferon

1 reference

12 December 2020

Hepatitis C virus (HCV) genotype, tissue HCV antigens, hepatocellular expression of HLA-A,B,C, and intercellular adhesion-1 molecules. Clues to pathogenesis of hepatocellular damage and response to interferon treatment in patients with chronic hepat

1 reference

12 December 2020

Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region

1 reference

12 December 2020

Frequent patient-to-patient transmission of hepatitis C virus in a haematology ward

1 reference

12 December 2020

The role of hepatitis C virus in fulminant viral hepatitis in an area with endemic hepatitis A and B.

1 reference

12 December 2020

Nuclear localization of the truncated hepatitis C virus core protein with its hydrophobic C terminus deleted

1 reference

12 December 2020

Diversity of quasispecies in various disease stages of chronic hepatitis C virus infection and its significance in interferon treatment

1 reference

12 December 2020

Analysis of the hepatitis C virus genome in patients with anti-LKM-1 autoantibodies

1 reference

12 December 2020

Classification of hepatitis C viruses based on phylogenetic analysis of the envelope 1 and nonstructural 5B regions and identification of five additional subtypes

1 reference

12 December 2020

Detection of three types of hepatitis C virus in blood donors: investigation of type-specific differences in serologic reactivity and rate of alanine aminotransferase abnormalities

1 reference

12 December 2020

Quantitation and typing of serum hepatitis C virus RNA in patients with chronic hepatitis C treated with interferon-beta

1 reference

12 December 2020

Multicycle infection of hepatitis C virus in cell culture and inhibition by alpha and beta interferons

1 reference

12 December 2020

Processing of E1 and E2 glycoproteins of hepatitis C virus expressed in mammalian and insect cells

1 reference

12 December 2020

Hepatitis C virus genotyping by means of 5'-UR/core line probe assays and molecular analysis of untypeable samples

1 reference

12 December 2020

Comparative studies of the core gene products of two different hepatitis C virus isolates: two alternative forms determined by a single amino acid substitution

1 reference

12 December 2020

Patients with chronic hepatitis C have circulating cytotoxic T cells which recognize hepatitis C virus-encoded peptides binding to HLA-A2.1 molecules

1 reference

12 December 2020

Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization

1 reference

12 December 2020

Genetic heterogeneity of hepatitis C virus: quasispecies and genotypes

1 reference

12 December 2020

Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources

1 reference

12 December 2020

Factors predictive of response to interferon-alpha therapy in hepatitis C virus infection

1 reference

12 December 2020

The degree of variability in the amino terminal region of the E2/NS1 protein of hepatitis C virus correlates with responsiveness to interferon therapy in viremic patients

1 reference

12 December 2020

Superinfection of chimpanzees carrying hepatitis C virus of genotype II/1b with that of genotype III/2a or I/1a

1 reference

12 December 2020

The course of hepatitis C virus infection after liver transplantation

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02087872

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29 September 2017

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PubMed ID

9011478