(Q41344092)

29 September 2017

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title

Methylene chloride induced mouse liver and lung tumours: an overview of the role of mechanistic studies in human safety assessment (English)

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29 September 2017

T Green

1

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29 September 2017

publication date

1 January 1997

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Human & Experimental Toxicology

29 September 2017

published in

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29 September 2017

volume

16

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29 September 2017

issue

1

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29 September 2017

page(s)

3-13

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A two-year drinking-water study of dichloromethane in rodents. II. Mice.

29 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F0960327197016001021

A two-year drinking-water study of dichloromethane in rodents. I. Rats.

21 January 2018

1 reference

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The metabolic activation of dichloromethane and chlorofluoromethane in a bacterial mutation assay using Salmonella typhimurium

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327197016001021

Mutagenicity testing of dichloromethane in short-term mammalian test systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327197016001021

Induction of chromosome damage by methylene chloride in CHO cells

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327197016001021

Inhalation exposure to a hepatocarcinogenic concentration of methylene chloride does not induce sustained replicative DNA synthesis in hepatocytes of female B6C3F1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327197016001021

Ras proto-oncogene activation in liver and lung tumors from B6C3F1 mice exposed chronically to methylene chloride

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327197016001021

Metabolism of dihalomethanes to carbon monoxide--III. Studies on the mechanism of the reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327197016001021

Metabolism of dihalomethanes to formaldehyde and inorganic halide--II. Studies on the mechanism of the reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327197016001021

Metabolism of inhaled dihalomethanes in vivo: Differentiation of kinetic constants for two independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327197016001021

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327197016001021

In vitro metabolism of methylene chloride in human and animal tissues: use in physiologically based pharmacokinetic models

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327197016001021

Methylene chloride-induced DNA damage: an interspecies comparison

21 January 2018

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Metabolism of dichloromethane (methylene chloride) to formaldehyde in human erythrocytes: influence of polymorphism of glutathione transferase theta (GST T1-1).

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327197016001021

Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism

21 January 2018

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Physiologically based pharmacokinetics and the risk assessment process for methylene chloride.

21 January 2018

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Effect of varying exposure regimens on methylene chloride-induced lung and liver tumors in female B6C3F1 mice.

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327197016001021

Hepatic and pulmonary carcinogenicity of methylene chloride in mice: a search for mechanisms.

21 January 2018

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Sequence analysis and expression of the bacterial dichloromethane dehalogenase structural gene, a member of the glutathione S-transferase supergene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327197016001021

Expression of mammalian glutathione S-transferase 5-5 in Salmonella typhimurium TA1535 leads to base-pair mutations upon exposure to dihalomethanes

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327197016001021

The role of formaldehyde and S-chloromethylglutathione in the bacterial mutagenicity of methylene chloride

21 January 2018

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https://api.crossref.org/works/10.1177%2F0960327197016001021

DNA sequence analysis of methylene chloride-induced HPRT mutations in Chinese hamster ovary cells: comparison with the mutation spectrum obtained for 1,2-dibromoethane and formaldehyde.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327197016001021

Dichloromethane (methylene chloride): metabolism to formaldehyde and formation of DNA-protein cross-links in B6C3F1 mice and Syrian golden hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327197016001021

The distribution of theta-class glutathione S-transferases in the liver and lung of mouse, rat and human

21 January 2018

1 reference

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Occupational exposure to chlorinated aliphatic hydrocarbons and risk of astrocytic brain cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327197016001021

10.1177/0960327197016001021

21 January 2018

Identifiers

DOI

1 reference

29 September 2017

1 reference