(Q41355735)

29 September 2017

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title

Challenge to the simple paradigm that 'carcinogens' are 'mutagens' and to the in vitro and in vivo assays used to test the paradigm (English)

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29 September 2017

Trosko JE

1

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29 September 2017

language of work or name

English

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publication date

1 February 1997

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29 September 2017

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29 September 2017

volume

373

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29 September 2017

issue

2

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29 September 2017

page(s)

245-249

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Detroit fluoride conference

29 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

A new paradigm is needed in toxicology evaluation.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

'A failed paradigm: carcinogenesis is more than mutagenesis'.

7 January 2021

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The role of modulated gap junctional intercellular communication in epigenetic toxicology

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

The role of tumor promoters on phenotypic alterations affecting intercellular communication and tumorigenesis

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

N-nitroso-N-methylurea-induced rat mammary tumors arise from cells with preexisting oncogenic Hras1 gene mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

Inhibition of intercellular communication by 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like PCBs in mouse hepatoma cells (Hepa1c1c7): involvement of the Ah receptor

7 January 2021

1 reference

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Inhibition of gap junctional intercellular communication by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rat hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

In vitro inhibition of gap junctional intercellular communication by chemical carcinogens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

Liver carcinogenesis is not a predicted outcome of chemically induced hepatocyte proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

Cell proliferation not associated with carcinogenesis in rodents and humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

Increasing the susceptibility of the rat 208F fibroblast cell line to radiation-induced apoptosis does not alter its clonogenic survival dose-response

7 January 2021

1 reference

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Cell death by apoptosis and its protective role against disease

7 January 2021

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Cell death: the significance of apoptosis

7 January 2021

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Membranes as sensitive targets in thymocyte apoptosis

7 January 2021

1 reference

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Characterization of radiation-induced apoptosis in the small intestine and its biological implications

7 January 2021

1 reference

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Redox Regulation of Programmed Cell Death in Lymphocytes

7 January 2021

1 reference

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The role of intracellular oxidants in apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

Chemical carcinogens and ras gene activation

7 January 2021

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Transcriptional and post-transcriptional responses to DNA-damaging agents

7 January 2021

1 reference

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Differential phosphorylation of the gap junction protein connexin43 in junctional communication-competent and -deficient cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

Hypomethylation of DNA: an epigenetic mechanism involved in tumor promotion

7 January 2021

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Biological consequences of gene regulation after ionizing radiation exposure

7 January 2021

1 reference

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Comments on the evidence in support of the epigenetic nature of radiogenic initiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

Effect of temperature and exogenous dibutyryl c-AMP on the recovery of UV-induced ouabain-resistant Chinese hamster cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens

7 January 2021

1 reference

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Mutation induction by okadaic acid, a protein phosphatase inhibitor, in CHL cells, but not in S. typhimurium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

Evaluation of the carcinogenic potential of 2,4-dinitrofluorobenzene and its implications regarding mutagenicity testing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

Tumor-promoting activity of 2,4-dinitrofluorobenzene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

Multistage carcinogenesis involves multiple genes and multiple mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

inferred from DOI database lookup

7 January 2021

based on heuristic

In vitro reversion of transformed phenotype in mouse C3H/10T1/2 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2896%2900203-5

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0027-5107(96)00203-5

1 reference

29 September 2017

1 reference