(Q41360655)

English

Functional evidence that transmembrane 12 and the loop between transmembrane 11 and 12 form part of the drug-binding domain in P-glycoprotein encoded by MDR1.

scientific article published on March 1995

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scholarly article

1 reference

Europe PubMed Central

29 September 2017

Functional evidence that transmembrane 12 and the loop between transmembrane 11 and 12 form part of the drug-binding domain in P-glycoprotein encoded by MDR1. (English)

1 reference

Europe PubMed Central

29 September 2017

transmembrane protein

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author name string

Zhang X

1

1 reference

Europe PubMed Central

29 September 2017

Collins KI

2

1 reference

Europe PubMed Central

29 September 2017

Greenberger LM

3

1 reference

Europe PubMed Central

29 September 2017

language of work or name

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publication date

1 March 1995

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Europe PubMed Central

29 September 2017

number of pages

8

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

29 September 2017

270

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Europe PubMed Central

29 September 2017

10

1 reference

Europe PubMed Central

29 September 2017

5441-5448

1 reference

Europe PubMed Central

29 September 2017

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

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21 January 2018

Functional expression of P-glycoprotein encoded by the mouse mdr3 gene in yeast cells

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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

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Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein

1 reference

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21 January 2018

The multidrug resistance (mdr1) gene product functions as an ATP channel

1 reference

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21 January 2018

Analysis of the steady-state and initial rate of doxorubicin efflux from a series of multidrug-resistant cells expressing different levels of P-glycoprotein

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21 January 2018

Tracing the roots of ion channels

1 reference

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ATP-binding cassette proteins Common denominators between ion channels, transporters, and enzymes

1 reference

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21 January 2018

Molecular determinants of state-dependent block of Na+ channels by local anesthetics

1 reference

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21 January 2018

Evidence that the S6 segment of the Shaker voltage-gated K+ channel comprises part of the pore

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5441

21 January 2018

Receptor sites for Ca2+ channel antagonists

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5441

21 January 2018

Sequence of mdr3 cDNA encoding a human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5441

21 January 2018

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

1 reference

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21 January 2018

Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells

1 reference

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21 January 2018

Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities

1 reference

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21 January 2018

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

1 reference

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21 January 2018

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

1 reference

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21 January 2018

Phosphatidylcholine translocase: a physiological role for the mdr2 gene

1 reference

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21 January 2018

Functional analysis of chimeric genes obtained by exchanging homologous domains of the mouse mdr1 and mdr2 genes

1 reference

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21 January 2018

Cell surface antigens of human malignant melanoma: mixed hemadsorption assays for humoral immunity to cultured autologous melanoma cells

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21 January 2018

The structure of the major immediate early gene of human cytomegalovirus strain AD169.

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21 January 2018

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

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21 January 2018

A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells

1 reference

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21 January 2018

High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5441

21 January 2018

Design of PCR primers that detect only mRNA in the presence of DNA.

1 reference

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21 January 2018

A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps

1 reference

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21 January 2018

Amino acid substitutions in the sixth transmembrane domain of P-glycoprotein alter multidrug resistance

1 reference

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21 January 2018

Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity

1 reference

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21 January 2018

Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum

1 reference

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21 January 2018

Additivity of mutational effects in proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5441

21 January 2018

Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.270.10.5441

21 January 2018

Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185----Val-185 substitution in P-glycoprotein

1 reference

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21 January 2018

Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis

1 reference

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21 January 2018

Membrane orientation of transmembrane segments 11 and 12 of MDR- and non-MDR-associated P-glycoproteins.

1 reference

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21 January 2018

Identifiers

10.1074/JBC.270.10.5441

1 reference

Europe PubMed Central

29 September 2017

1 reference

Europe PubMed Central

29 September 2017

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