(Q41362966)

29 September 2017

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title

T cells of lupus and molecular targets for immunotherapy (English)

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29 September 2017

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Datta SK

1

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29 September 2017

Kaliyaperumal A

series ordinal

2

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29 September 2017

Desai-Mehta A

series ordinal

3

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29 September 2017

language of work or name

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1 January 1997

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Journal of Clinical Immunology

29 September 2017

published in

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29 September 2017

volume

17

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29 September 2017

issue

1

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29 September 2017

page(s)

11-20

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Generation and characterization of cloned T helper cell lines for anti-DNA responses in NZB.H-2bm12 mice

29 September 2017

cites work

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12 December 2020

Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites

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12 December 2020

Glomerular binding activity in MRL lpr serum consists of antibodies that bind to a DNA/histone/type IV collagen complex

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12 December 2020

Histones have high affinity for the glomerular basement membrane. Relevance for immune complex formation in lupus nephritis

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12 December 2020

The NZB X SWR model of lupus nephritis. II. Autoantibodies deposited in renal lesions show a distinctive and restricted idiotypic diversity

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12 December 2020

Junctional region sequences of T-cell receptor beta-chain genes expressed by pathogenic anti-DNA autoantibody-inducing helper T cells from lupus mice: possible selection by cationic autoantigens

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12 December 2020

Induction of bcl-x by CD40 engagement rescues sIg-induced apoptosis in murine B cells

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12 December 2020

Viruses and Systemic Lupus Erythematosus

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12 December 2020

CD4+ T cell lines with selective patterns of autoreactivity as well as CD4- CD8- T helper cell lines augment the production of idiotypes shared by pathogenic anti-DNA autoantibodies in the NZB x SWR model of lupus nephritis

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12 December 2020

B cells process and present lupus autoantigens that initiate autoimmune T cell responses

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12 December 2020

Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA.

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12 December 2020

Polygenic control of susceptibility to murine systemic lupus erythematosus

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12 December 2020

Mendelian segregation of loci controlling xenotropic virus production in NZB crosses

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12 December 2020

Cationic residues in pathogenic anti-DNA autoantibodies arise by mutations of a germ-line gene that belongs to a large VH gene subfamily

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12 December 2020

Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation

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12 December 2020

VH-gene representation in autoantibodies reflects the normal human B-cell repertoire

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12 December 2020

The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice.

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12 December 2020

Costimulation through CD28 enhances T cell-dependent B cell activation via CD40-CD40L interaction

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12 December 2020

TCR/CD3 complex-mediated signal transduction pathway in T cells and T cell lines from patients with systemic lupus erythematosus

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12 December 2020

Presence of nucleosome-restricted antibodies in patients with systemic lupus erythematosus

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12 December 2020

A genetic association between systemic lupus erythematosus and tumor necrosis factor alpha

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12 December 2020

T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis

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12 December 2020

The BM12 mutation and autoantibodies to dsDNA in NZB.H-2bm12 mice

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12 December 2020

Analysis of recombinant inbred lines derived from "autoimmune" (NZB) and "high leukemia" (C58) strains: independent multigenic systems control B cell hyperactivity, retrovirus expression, and autoimmunity

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12 December 2020

Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus

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12 December 2020

T cell receptor V beta genes expressed by IgG anti-DNA autoantibody-inducing T cells in lupus nephritis: forbidden receptors and double-negative T cells

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12 December 2020

Novel autoimmune phenomena induced in vivo by a new DNA binding protein Nuc: a study on MRL/n mice.

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12 December 2020

How B and T cells talk to each other

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12 December 2020

Antibodies to histones in systemic lupus erythematosus: localization of prominent autoantigens on histones H1 and H2B.

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12 December 2020

A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively

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12 December 2020

Genesis of antinuclear antibody in NZB-W mice: role of genetic factors and of viral infections

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12 December 2020

Dominance and crypticity of T cell antigenic determinants

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12 December 2020

The CD40 ligand expressed by human B cells costimulates B cell responses

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12 December 2020

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12 December 2020

The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus

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12 December 2020

T-BAM/CD40-L on helper T lymphocytes augments lymphokine-induced B cell Ig isotype switch recombination and rescues B cells from programmed cell death

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12 December 2020

Hypercross-linking surface IgM or IgD receptors on mature B cells induces apoptosis that is reversed by costimulation with IL-4 and anti-CD40

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12 December 2020

Deficient type I protein kinase A isozyme activity in systemic lupus erythematosus T lymphocytes

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12 December 2020

Responsiveness of autoimmune and normal mice to nucleic acid antigens

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12 December 2020

Xenotropic C-type viruses and autoimmune disease

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12 December 2020

Possible pathogenic role of cationic anti-DNA autoantibodies in the development of nephritis in patients with systemic lupus erythematosus.

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12 December 2020

Intrinsic B cell defects in NZB and NZW mice contribute to systemic lupus erythematosus in (NZB x NZW)F1 mice.

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12 December 2020

Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation: implications for antibody vs. T cell-mediated autoimmunity

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12 December 2020

Lupus: Key Pathogenic Mechanisms and Contributing Factors

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12 December 2020

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12 December 2020

T cells responsive to myelin basic protein in patients with multiple sclerosis

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12 December 2020

Type-C RNA virus gene expression in human tissue

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12 December 2020

Immunologic and viral factors in the pathogenesis of systemic lupus erythematosus

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12 December 2020

The regulation of the expression of gp39, the CD40 ligand, on normal and cloned CD4+ T cells.

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12 December 2020

Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production

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12 December 2020

Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus

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12 December 2020

Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion

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12 December 2020

Structural properties of a subset of nephritogenic anti-DNA antibodies

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12 December 2020

Genetics of expression of xenotropic virus and autoimmunity in NZB mice

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12 December 2020

Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 mice

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12 December 2020

Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes

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12 December 2020

Mechanisms of T and B cell collaboration in the in vitro production of anti-DNA antibodies in the NZB/NZW F1 murine SLE model

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12 December 2020

T-cell-receptor beta- and I-A beta-chain genes of normal SWR mice are linked with the development of lupus nephritis in NZB x SWR crosses

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12 December 2020

A search for the underlying mechanisms of systemic autoimmune disease in the NZB x SWR model

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12 December 2020

Initiation of autoimmunity to the p53 tumor suppressor protein by complexes of p53 and SV40 large T antigen

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12 December 2020

Mechanisms of autoantibody production in autoimmune MRL mice

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12 December 2020

CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway

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12 December 2020

Purification and characterization of the Fas-ligand that induces apoptosis

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12 December 2020

Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal

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12 December 2020

Fc gamma RIIA alleles are heritable risk factors for lupus nephritis in African Americans

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12 December 2020

Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion

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12 December 2020

Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus

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12 December 2020

CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation

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12 December 2020

Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB x NZW)F1 mice

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12 December 2020

Immunohistologic analysis of ineffective CD40-CD40 ligand interaction in lymphoid tissues from patients with X-linked immunodeficiency with hyper-IgM. Abortive germinal center cell reaction and severe depletion of follicular dendritic cells.

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12 December 2020

Mechanisms of the pathogenic autoimmune response in lupus: prospects for specific immunotherapy

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12 December 2020

Restricted subpopulations of DNA antibodies in kidneys of mice with systemic lupus. Comparison of antibodies in serum and renal eluates

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12 December 2020

Th2 cell clonal anergy as a consequence of partial activation

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12 December 2020

The Specificity and Regulation of T-Cell Responsiveness to Allergens

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12 December 2020

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

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12 December 2020

Cationic and high affinity serum IgG anti-dsDNA antibodies in active lupus nephritis

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12 December 2020

Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy

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12 December 2020

C-Type Virus Expression in Systemic Lupus Erythematosus

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12 December 2020

Selective production of autoantibodies in graft-vs-host-induced and spontaneous murine lupus. Predominant reactivity with histone regions accessible in chromatin

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12 December 2020

Differentiation and stability of T helper 1 and 2 cells derived from naive human neonatal CD4+ T cells, analyzed at the single-cell level

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12 December 2020

V region sequences of an idiotypically connected family of pathogenic anti-DNA autoantibodies

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12 December 2020

T cell receptor alpha-chain repertoire of pathogenic autoantibody-inducing T cells in lupus mice

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12 December 2020

The NZB X SWR model of lupus nephritis. I. Cross-reactive idiotypes of monoclonal anti-DNA antibodies in relation to antigenic specificity, charge, and allotype. Identification of interconnected idiotype families inherited from the normal SWR and th

1 reference

12 December 2020

Genetic studies of autoimmunity and retrovirus expression in crosses of New Zealand black mice. II. The viral envelope glycoprotein gp70

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12 December 2020

Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen

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12 December 2020

Antigen-specific induction of antibodies against native mammalian DNA in nonautoimmune mice

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12 December 2020

Mechanisms of autoimmunization: perspective from the mid-90s

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12 December 2020

Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen

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12 December 2020

B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40

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12 December 2020

Endogenous circulating DNA in systemic lupus erythematosus. Occurrence as multimeric complexes bound to histone

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12 December 2020

Origins of pathogenic anti-DNA idiotypes in the NZB X SWR model of lupus nephritis

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12 December 2020

Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis.

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12 December 2020

Induction of a cationic shift in IgG anti-DNA autoantibodies. Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis

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12 December 2020

Lupus susceptibility loci in New Zealand mice

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12 December 2020

A small proportion of cationic antibodies in immune complexes is sufficient to mediate their deposition in glomeruli

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12 December 2020

Binding of nucleosomes to a cell surface receptor: redistribution and endocytosis in the presence of lupus antibodies

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12 December 2020

New Zealand white rabbits immunized with RNA-complexed total histones develop an autoimmune-like response

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12 December 2020

In vivo expression of a single viral DNA-binding protein generates systemic lupus erythematosus-related autoimmunity to double-stranded DNA and histones

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12 December 2020

A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells

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12 December 2020

Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus

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12 December 2020

A model for disease heterogeneity in systemic lupus erythematosus. Relationships between histocompatibility antigens, autoantibodies, and lymphopenia or renal disease

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12 December 2020

Analysis of thymic endogenous retroviral expression in murine lupus. Genetic and immune studies

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12 December 2020

The role of somatic mutation in the pathogenic anti-DNA response

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12 December 2020

Ligation of B7 with CD28/CTLA-4 on T cells results in CD40 ligand expression, interleukin-4 secretion and efficient help for antibody production by B cells

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12 December 2020

A naturally occurring polyclonal B cell activator of normal and autoantibody responses

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12 December 2020

T-B collaboration for autoantibody production in lpr mice is cognate and MHC-restricted

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12 December 2020

Systemic lupus erythematosus: emerging concepts. Part 1: Renal, neuropsychiatric, cardiovascular, pulmonary, and hematologic disease

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12 December 2020

Induction of B cell costimulatory function by recombinant murine CD40 ligand

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12 December 2020

Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology

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12 December 2020

CD8+ lymphocytes from patients with systemic lupus erythematosus sustain, rather than suppress, spontaneous polyclonal IgG production and synergize with CD4+ cells to support autoantibody synthesis

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12 December 2020

On the biological origin of anti-double-stranded (ds) DNA antibodies: systemic lupus erythematosus-related anti-dsDNA antibodies are induced by polyomavirus BK in lupus-prone (NZBxNZW) F1 hybrids, but not in normal mice

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12 December 2020

T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus

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12 December 2020

The CD40 antigen and its ligand

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12 December 2020

Mechanism of antigen-driven selection in germinal centres

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12 December 2020

Genetic analysis of the NZB contribution to lupus-like autoimmune disease in (NZB x NZW)F1 mice

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12 December 2020

Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells.

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12 December 2020

Tumor necrosis factor (TNF) receptor expression in T lymphocytes. Differential regulation of the type I TNF receptor during activation of resting and effector T cells

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12 December 2020

The Immunology and Pathology of NZB Mice

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12 December 2020

Structure and specificity of T cell receptors expressed by potentially pathogenic anti-DNA autoantibody-inducing T cells in human lupus

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12 December 2020

Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B'-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity

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12 December 2020

In the absence of a CD40 signal, B cells are tolerogenic.

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12 December 2020

Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor

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12 December 2020

Structural characteristics of the variable regions of immunoglobulin genes encoding a pathogenic autoantibody in murine lupus

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12 December 2020

Anti-nucleosome antibodies complexed to nucleosomal antigens show anti-DNA reactivity and bind to rat glomerular basement membrane in vivo

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12 December 2020

The Relation of Immunoglobulin Class, Pattern of Antinuclear Antibody, and Complement-Fixing Antibodies to DNA in Sera from Patients with Systemic Lupus Erythematosus*

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12 December 2020

Genetic analysis of the inheritance of B cell hyperactivity in relation to the development of autoantibodies and glomerulonephritis in NZB x SWR crosses

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12 December 2020

Anti-idiotypic antibodies to the Coombs antibody in NZB F1 mice

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12 December 2020

Genetic and structural evidence for antigen selection of anti-DNA antibodies.

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12 December 2020

Plasma DNA in patients undergoing hemodialysis or hemofiltration: cytolysis in artificial kidney is responsible for the release of DNA in circulation

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12 December 2020

Pathogenic autoantibodies are routinely generated during the response to foreign antigen: a paradigm for autoimmune disease

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12 December 2020

Alterations of the hprt gene in human in vivo-derived 6-thioguanine-resistant T lymphocytes.

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12 December 2020

Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40

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12 December 2020

Molecular interactions mediating T-B lymphocyte collaboration in human lymphoid follicles. Roles of T cell-B-cell-activating molecule (5c8 antigen) and CD40 in contact-dependent help

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12 December 2020

Pathogenic anti-DNA autoantibody-inducing T helper cell lines from patients with active lupus nephritis: isolation of CD4-8- T helper cell lines that express the gamma delta T-cell antigen receptor

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12 December 2020

Type c viruses and systemic lupus erythematosus

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12 December 2020

C-type viruses in systemic lupus erythematosus

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12 December 2020

Genetic studies of autoimmunity and retrovirus expression in crosses of New Zealand black mice I. Xenotropic virus

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12 December 2020

Comparison of pathogenic and non-pathogenic murine antibodies to DNA: antigen binding and structural characteristics

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12 December 2020

Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenics

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12 December 2020

A systemic lupus erythematosus (SLE)-like disease in mice induced by abnormal T-B cell cooperation. Preferential formation of autoantibodies characteristic of SLE

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12 December 2020

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

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12 December 2020

The fruits of cooperation

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12 December 2020

A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency

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12 December 2020

Lupus prone (SWR x NZB)F1 mice produce potentially nephritogenic autoantibodies inherited from the normal SWR parent

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12 December 2020

Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas

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12 December 2020

Regulatory Mechanisms in the Immune Response to Cell-surface Antigens

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12 December 2020

Characterization of in vivo mutated T cell clones from patients with systemic lupus erythematosus

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12 December 2020

The viral envelope glycoprotein of murine leukemia virus and the pathogenesis of immune complex glomerulonephritis of New Zealand mice

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12 December 2020

Identifiers

DOI

10.1023/A:1027328226918

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Dimensions Publication ID

29 September 2017

1034600113

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