(Q41382841)

30 September 2017

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title

The state of the STATs: recent developments in the study of signal transduction to the nucleus (English)

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30 September 2017

Horvath CM

1

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PubMed ID

9069254

30 September 2017

Darnell JE

series ordinal

2

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30 September 2017

1 April 1997

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Current Opinion in Cell Biology

30 September 2017

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30 September 2017

9

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30 September 2017

233-239

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30 September 2017

2

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

30 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Stat3 and Stat4: members of the family of signal transducers and activators of transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

An interleukin-4-induced transcription factor: IL-4 Stat

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Distribution of the mammalian Stat gene family in mouse chromosomes

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

STAT signaling is active during early mammalian development.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Identification of a Stat gene that functions in Drosophila development.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Essential role of Stat6 in IL-4 signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Defective STAT signaling by the leptin receptor in diabetic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

A transcription factor with SH2 and SH3 domains is directly activated by an interferon alpha-induced cytoplasmic protein tyrosine kinase(s)

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Interaction of the transcriptional activator Stat-2 with the type I interferon receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Function of Stat2 protein in transcriptional activation by alpha interferon

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Requirements for interleukin-4-induced gene expression and functional characterization of Stat6

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Requirement of serine phosphorylation for formation of STAT-promoter complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Components of a Stat recognition code: evidence for two layers of molecular selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Combinatorial association and abundance of components of interferon-stimulated gene factor 3 dictate the selectivity of interferon responses.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Tyrosine-phosphorylated Stat1 and Stat2 plus a 48-kDa protein all contact DNA in forming interferon-stimulated-gene factor 3

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3 alpha subunit (or similar) molecule binds

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Differential activation of c-fos promoter elements by serum, lysophosphatidic acid, G proteins and polypeptide growth factors.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Stat1 depends on transcriptional synergy with Sp1.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Identification of the interleukin-6/oncostatin M response element in the rat tissue inhibitor of metalloproteinases-1 (TIMP-1) promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

A nuclear tyrosine phosphatase downregulates interferon-induced gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980067-1

7 January 2021

10.1016/S0955-0674(97)80067-1

Identifiers

DOI

1 reference

30 September 2017

1 reference

PubMed ID

9069254