(Q41384498)

30 September 2017

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title

Nef and PAK: virulence factor and cellular accomplice (English)

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30 September 2017

Trono D

1

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30 September 2017

Wang JK

series ordinal

2

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30 September 2017

publication date

1 January 1997

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30 September 2017

published in

Chemistry and Biology

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30 September 2017

volume

4

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30 September 2017

issue

1

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30 September 2017

page(s)

13-15

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Importance of the nef gene for maintenance of high virus loads and for development of AIDS

30 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

Activation of PAK by HIV and SIV Nef: importance for AIDS in rhesus macaques

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

JNK is involved in signal integration during costimulation of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

Mutational analysis of HIV-1 Nef: identification of two mutants that are temperature-sensitive for CD4 downregulation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

Regulation of receptor-mediated endocytosis by Rho and Rac.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2897%2990232-5

7 January 2021

10.1016/S1074-5521(97)90232-5

Identifiers

DOI

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30 September 2017

1 reference