(Q41393165)

English

Comparative study of the binding characteristics to and inhibitory potencies towards PARP and in vivo antidiabetogenic potencies of taurine, 3-aminobenzamide and nicotinamide

scientific article published on 24 August 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Comparative study of the binding characteristics to and inhibitory potencies towards PARP and in vivo antidiabetogenic potencies of taurine, 3-aminobenzamide and nicotinamide (English)

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

author name string

Kashyap G Pandya

1

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Maulik R Patel

2

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Cesar A Lau-Cam

3

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

publication date

24 August 2010

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Journal of Biomedical Science

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

17 Suppl 1

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

S16

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

PARP inhibitors: new partners in the therapy of cancer and inflammatory diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

Role of antioxidant activity of taurine in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

Poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors in cancer chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

Nicotinamide reverses neurological and neurovascular deficits in streptozotocin diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

O-GlcNAc modification of nucleocytoplasmic proteins and diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

PARP inhibitors for cancer therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

Tissue sulfhydryl groups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

Genotoxicity of streptozotocin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

The therapeutic potential of poly(ADP-ribose) polymerase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1,2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

Safety of high-dose nicotinamide: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

Effect of 17beta-oestradiol on cytokine-induced nitric oxide production in rat isolated aorta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

Free radicals and diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

New hypotheses for the mechanisms of streptozotocin and alloxan inducing diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

Protective actions of taurine against streptozotocin-induced hyperglycemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

1 October 2017

Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

11 June 2018

Protection from acetaminophen-induced liver damage by the synergistic action of low doses of the poly(ADP-ribose) polymerase-inhibitor nicotinamide and the antioxidant N-acetylcysteine or the amino acid L-methionine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

11 June 2018

Nicotinamide--biological actions and therapeutic potential in diabetes prevention. IDIG Workshop, Copenhagen, Denmark, 4-5 December 1992.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

11 June 2018

Taurine ameliorates chronic streptozocin-induced diabetic nephropathy in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

11 June 2018

Plasma glutathione and glutathione disulfide in the rat: regulation and response to oxidative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

11 June 2018

The antioxidant action of taurine, hypotaurine and their metabolic precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

11 June 2018

Supplemental taurine in diabetic rats: effects on plasma glucose and triglycerides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

11 June 2018

Peroxidative changes in experimental diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

11 June 2018

Parp1-XRCC1 and the repair of DNA double strand breaks in mouse round spermatids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Glutathione, ascorbic acid and antioxidant enzymes in the tumor tissue and blood of patients with oral squamous cell carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Nicotinamide protected first-phase insulin response (FPIR) and prevented clinical disease in first-degree relatives of type-1 diabetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Quercetin, a flavonoid antioxidant, prevents and protects streptozotocin-induced oxidative stress and beta-cell damage in rat pancreas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Protective effect of taurine against free radicals damage in the rat myocardium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Taurine supplement in early life altered islet morphology, decreased insulitis and delayed the onset of diabetes in non-obese diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Protective effect of nicotinamide on neuronal cells under oxygen and glucose deprivation and hypoxia/reoxygenation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

European Nicotinamide Diabetes Intervention Trial (ENDIT): a randomised controlled trial of intervention before the onset of type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Taurine supplementation reduces oxidative stress and improves cardiovascular function in an iron-overload murine model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Effect of poly(ADP-ribose) polymerase inhibitors on oxidative stress evoked hydroxyl radical level and macromolecules oxidation in cell free system of rat brain cortex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Oxidative stress in streptozotocin-induced diabetic rats: effects of garlic oil and melatonin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Free radicals and the pathogenesis of type 1 diabetes: beta-cell cytokine-mediated free radical generation via cyclooxygenase-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Poly (ADP-ribose) polymerase inhibition prevents spontaneous and recurrent autoimmune diabetes in NOD mice by inducing apoptosis of islet-infiltrating leukocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Poly(ADP-ribose)polymerase activation determines strain sensitivity to streptozotocin-induced beta cell death in inbred mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Hypoglycemic properties of taurine: not mediated by enhanced insulin release.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2994389

19 August 2018

Implicating PARP and NAD+ depletion in type I diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the enzymatic determination of blood glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible protective effect of melatonin and/or desferrioxamine against streptozotocin-induced hyperglycaemia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scavenging effect of nicorandil on free radicals and lipid peroxide in streptozotocin-induced diabetic rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid peroxidation in nicotinamide-deficient and nicotinamide-supplemented rats with streptozotocin-induced diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vanadyl sulfate, taurine, and combined vanadyl sulfate and taurine treatments in diabetic rats: effects on the oxidative and antioxidative systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microsomal lipid peroxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement by streptozotocin of O2- radical generation by the xanthine oxidase system of pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection by 3-aminobenzamide and nicotinamide against streptozotocin-induced beta-cell toxicity in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Streptozocin- and Alloxan-Induced H2O2 Generation and DNA Fragmentation in Pancreatic Islets: H2O2 as Mediator for DNA Fragmentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taurine prevents glucose-induced lipid peroxidation and increased collagen production in cultured rat mesangial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protective effect of taurine on the biomembrane against damage produced by oxygen radicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of nicotinamide in the prevention of type 1 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20804590

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1423-0127-17-S1-S16

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

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