(Q41393635)

30 September 2017

Comparative in vitro cytotoxic effects of taxol and its major human metabolite 6 alpha-hydroxytaxol (English)

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30 September 2017

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G Kumar

1

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30 September 2017

S Ray

2

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30 September 2017

T Walle

3

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30 September 2017

Y Huang

4

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30 September 2017

M Willingham

5

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30 September 2017

S Self

6

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30 September 2017

K Bhalla

7

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30 September 2017

1 January 1995

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Cancer Chemotherapy and Pharmacology

30 September 2017

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30 September 2017

36

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30 September 2017

129-135

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30 September 2017

2

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Taxol stabilizes microtubules in mouse fibroblast cells

30 September 2017

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12 December 2020

Cytochrome P450 3A-mediated human liver microsomal taxol 6 alpha-hydroxylation.

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12 December 2020

6 alpha-Hydroxytaxol: isolation and identification of the major metabolite of taxol in human liver microsomes

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12 December 2020

Taxol induces internucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cells

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12 December 2020

Reversible assembly purification of microtubules without assembly-promoting agents and further purification of tubulin, microtubule-associated proteins, and MAP fragments.

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12 December 2020

Phase I and pharmacodynamic study of taxol in refractory acute leukemias.

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12 December 2020

Structure-activity study of cytotoxicity and microtubule assembly in vitro by taxol and related taxanes

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12 December 2020

Taxol-induced flexibility of microtubules and its reversal by MAP-2 and Tau

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12 December 2020

Isolation, structural determination, and biological activity of 6 alpha-hydroxytaxol, the principal human metabolite of taxol

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12 December 2020

Characterization of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytic leukemia

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12 December 2020

Phase I trial of taxol given as a 24-hour infusion every 21 days: responses observed in metastatic melanoma.

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12 December 2020

Taxol: an antimitotic agent with a new mechanism of action

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12 December 2020

Taxol binds to polymerized tubulin in vitro

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12 December 2020

Turbidimetric studies of the in vitro assembly and disassembly of porcine neurotubules.

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12 December 2020

Apoptosis or programmed cell death

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12 December 2020

Taxol metabolism by human liver microsomes: identification of cytochrome P450 isozymes involved in its biotransformation

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12 December 2020

Transient mitotic phase localization of bcl-2 oncoprotein in human carcinoma cells and its possible role in prevention of apoptosis

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12 December 2020

Taxol: the first of the taxanes, an important new class of antitumor agents.

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12 December 2020

Characterization of a human myeloid leukemia cell line highly resistant to taxol

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12 December 2020

Hepatic metabolism and biliary excretion of Taxol in rats and humans

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12 December 2020

Rapid, simultaneous measurement of DNA, protein, and cell volume in single cells from large mammalian cell populations

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12 December 2020

Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol.

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12 December 2020

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations

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12 December 2020

Identifiers

DOI

10.1007/S002800050297

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30 September 2017

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