(Q41429416)

30 September 2017

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title

On the role of DNA double-strand breaks in toxicity and carcinogenesis (English)

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30 September 2017

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Vamvakas S

1

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30 September 2017

Vock EH

series ordinal

2

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30 September 2017

Lutz WK

series ordinal

3

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30 September 2017

language of work or name

English

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publication date

1 March 1997

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Critical Reviews in Toxicology

30 September 2017

published in

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30 September 2017

volume

27

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30 September 2017

issue

2

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30 September 2017

page(s)

155-174

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The Origins of DNA Breaks: A Consequence of DNA Damage, DNA Repair, or Apoptosis?

30 September 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Measurement of low levels of x-ray mutagenesis in relation to human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Oncogenic transformation of murine C3H 10T1/2 cells resulting from DNA double-strand breaks induced by a restriction endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Significance and measurement of DNA double strand breaks in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Cell death in health and disease: the biology and regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Programmed death of autoreactive thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Modulation of neocarzinostatin-mediated DNA double strand damage by activating thiol: deuterium isotope effects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Sequence-specific double-strand cleavage of DNA by Fe-bleomycin. 1. The detection of sequence-specific double-strand breaks using hairpin oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Sequence-specific double-strand cleavage of DNA by Fe-bleomycin. 2. Mechanism and dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Intragenomic heterogeneity of DNA damage formation and repair: a review of cellular responses to covalent drug DNA interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

DNA double-strand breaks induced in normal human cells during the repair of ultraviolet light damage

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Studies on mammalian mutants defective in rejoining double-strand breaks in DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

The yield of DNA double-strand breaks produced intracellularly by ionizing radiation: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

DNA single- and double-strand breaks produced by ferric nitrilotriacetate in relation to renal tubular carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Oxidative stress in chemical toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Carcinogenic properties of pharmaceutical agents evaluated in the IARC Monographs programme

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

DNA damage resulting from the oxidation of hydroquinone by copper: role for a Cu(II)/Cu(I) redox cycle and reactive oxygen generation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Spontaneous cleavage of bleomycin-induced abasic sites in chromatin and their mutagenicity in mammalian shuttle vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Dna strand breakage in isolated nuclei subjected to bleomycin or hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Differential role of hydrogen peroxide and organic peroxides in augmenting asbestos-mediated DNA damage: implications for asbestos induced carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

DNA topoisomerase poisons as antitumor drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

International Commission for Protection Against Environmental Mutagens and Carcinogens. Mutagenicity and carcinogenicity of topoisomerase-interactive agents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

c-myc and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Instability of the monofunctional adducts in cis-[Pt(NH3)2(N7-N-methyl-2-diazapyrenium)Cl](2+)-modified DNA: rates of cross-linking reactions in cis-platinum-modified DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

The role of Ca2+ in cell killing

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Calcium-Mediated Mechanisms in Chemically Induced Cell Death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Ca(2+)-dependent mechanisms of cytotoxicity and programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Formation of 50 kbp chromatin fragments in isolated liver nuclei is mediated by protease and endonuclease activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Escape from the antiproliferative effect of transforming growth factor-beta 1 in LLC-PK1 renal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

A comparative study of rejoining of DNA double-strand breaks in yeast irradiated with 3.5 MeV alpha-particles or with 30 MeV electrons

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Molecular dissection of mammalian gene amplification: new mechanistic insights revealed by analyses of very early events

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Active oxygen induced DNA strand breakage and poly ADP-ribosylation in promotable and non-promotable JB6 mouse epidermal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Pathophysiological mechanisms of active oxygen

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Apoptosis: molecular control point in toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Mechanisms of apoptosis: integration of genetic, biochemical, and cellular indicators

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

The regulatory role of zinc in apoptosis in human tumour cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

The role of calcium in the induction of apoptosis in human tumour cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Characterization of a renal epithelial cell model of apoptosis using okadaic acid and the NRK-52E cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Cleavage of DNA to large kilobase pair fragments occurs in some forms of necrosis as well as apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

p53 status, DNA double-strand break repair proficiency, and radiation response of mouse lymphoid and myeloid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

p53 expression in nitric oxide‐induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Faster repair of DNA double-strand breaks in radioresistant human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Radiation-induced DNA double-strand break rejoining in human tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Regional assignment of a human DNA repair gene (XRCC5) to 2q35 by X-ray hybrid mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Recombination and repair. Ku starts at the end.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Absence of autoantigen Ku in mature human neutrophils and human promyelocytic leukemia line (HL-60) cells and lymphocytes undergoing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Disruption of DNA-PK in Ku80 mutant xrs-6 and the implications in DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate gamma-irradiation as assayed by pulsed field gel electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

DNA double-strand break induction and rejoining as determinants of human tumour cell radiosensitivity. A pulsed-field gel electrophoresis study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Poly(ADP-ribosyl)ation, DNA strand breaks, chromatin and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Poly(ADP-ribose): historical perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Events that precede and that follow S-(1,2-dichlorovinyl)-L-cysteine-induced release of mitochondrial Ca2+ and their association with cytotoxicity to renal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Possible involvement of arachidonic acid metabolism in phenobarbital promotion of hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

A comparative study on the effect of tumor promoters on poly ADP-ribosylation in A431 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Possible involvement of poly ADP-ribosylation in phenobarbital promotion of rat hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Induction, repair and biological relevance of radiation-induced DNA lesions in eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

DNA double-strand breaks in mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Oncogenic transfonnation by charged particles of defined LET

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Chromose aberrations in human lymphocytes after irradiation with 15.0-MeV neutrons in vitro I. Dose-response relation and RBE

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Use of restriction endonucleases to study relationships between DNA double-strand breaks, chromosomal aberrations and other end-points in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Cytogenetical characterization of Chinese hamster ovary X-ray-sensitive mutant cells, xrs 5 and xrs 6. IV. Study of chromosomal aberrations and sister-chromatid exchanges by restriction endonucleases and inhibitors of DNA topoisomerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Relationship between topoisomerase II and radiosensitivity in mouse L5178Y lymphoma strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Induction of poly(ADP-ribosyl)ation in the kidney after in vivo application of renal carcinogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

DNA double-strand break analysis by CHEF (clamped homogeneous electrical field) electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Pulsed field electrophoresis in contour-clamped homogeneous electric fields for the resolution of DNA by size or topology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Calibration of pulsed field gel electrophoresis for measurement of DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Induction of double-strand breaks in Chinese hamster ovary cells at two different dose rates of gamma-irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Simultaneous determination of DNA double strand breaks and DNA fragment size in cultured mammalian cells exposed to hydrogen peroxide/histidine or etoposide with CHEF electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

The single cell gel electrophoresis assay (comet assay): a European review

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Genomic instability in neoplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

DNA double-strand breaks measured by pulsed-field gel electrophoresis in irradiated lymphocytes from normal humans and those with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Analysis of DNA fragmentation in human uterine cervix carcinoma HeLa S3 cells treated with duocarmycins or other antitumor agents by pulse field gel electrophoresis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Use of pulsed-field gel electrophoresis to investigate factors influencing the measurement of DNA double-strand breaks in human brain tumour specimens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Mapping and chromosome analysis: the potential of fluorescence in situ hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Tumor development and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

Role of nucleases in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

The quality of DNA double-strand breaks: A Monte Carlo simulation of the end-structure of strand breaks produced by protons and alpha particles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408449709021617

10.3109/10408449709021617

21 January 2018

Identifiers

DOI

1 reference

30 September 2017

1 reference