(Q41429633)

30 September 2017

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title

Mechanisms of selection and differentiation in germinal centers (English)

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30 September 2017

Liu YJ

1

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30 September 2017

de Bouteiller O

series ordinal

2

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30 September 2017

Fugier-Vivier I

series ordinal

3

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30 September 2017

publication date

1 April 1997

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Current Opinion in Immunology

30 September 2017

published in

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30 September 2017

volume

9

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30 September 2017

issue

2

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30 September 2017

page(s)

256-262

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Clonal selection and learning in the antibody system

30 September 2017

cites work

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Biology of germinal centers in lymphoid tissue

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Developmental switches in the immune system

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7 January 2021

Differentiation of the secondary B-lymphocyte repertoire: the germinal center reaction

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7 January 2021

Somatic mutation and memory

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7 January 2021

Mechanism of antigen-driven selection in germinal centres

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Human germinal center B cells express the apoptosis-inducing genes Fas, c-myc, P53, and Bax but not the survival gene bcl-2

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Induction of apoptosis in fibroblasts by c-myc protein

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Transfection of the c-myc oncogene into normal Epstein-Barr virus-harboring B cells results in new phenotypic and functional features resembling those of Burkitt lymphoma cells and normal centroblasts

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7 January 2021

Antigen-driven selection of virgin and memory B cells

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7 January 2021

Antigen-driven B cell differentiation in vivo

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Germinal center founder cells display propensity for apoptosis before onset of somatic mutation

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7 January 2021

Accumulation of somatic mutants in the B cell compartment after primary immunization with a T cell-dependent antigen

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7 January 2021

Soluble antigen profoundly reduces memory B-cell numbers even when given after challenge immunization

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7 January 2021

Antigen-induced B-cell death and elimination during germinal-centre immune responses

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7 January 2021

Soluble antigen can cause enhanced apoptosis of germinal-centre B cells.

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7 January 2021

CD40 and B cell antigen receptor dual triggering of resting B lymphocytes turns on a partial germinal center phenotype

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7 January 2021

Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires

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7 January 2021

Positive selection of lymphocytes

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Activation of Epstein-Barr virus latent genes protects human B cells from death by apoptosis

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7 January 2021

Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens

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7 January 2021

The dynamic relationship between B-cell populations in adults

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7 January 2021

Suppression of apoptosis in normal and neoplastic human B lymphocytes by CD40 ligand is independent of Bc1-2 induction

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7 January 2021

B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40

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7 January 2021

Antibodies to murine CD40 protect normal and malignant B cells from induced growth arrest.

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7 January 2021

Growing human B lymphocytes in the CD40 system

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7 January 2021

How B and T cells talk to each other

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Generation of memory B cells and plasma cells in vitro.

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7 January 2021

CD40 ligand-independent B cell activation revealed by CD40 ligand-deficient T cell clones: evidence for distinct activation requirements for antibody formation and B cell proliferation

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7 January 2021

CD40 cross-linking inhibits specific antibody production by human B cells.

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7 January 2021

CD40 and its ligand in host defense

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7 January 2021

A subset of CD4+ memory T cells contains preformed CD40 ligand that is rapidly but transiently expressed on their surface after activation through the T cell receptor complex

1 reference

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7 January 2021

Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid up-regulation of B7-1 and B7-2.

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7 January 2021

Fas ligation induces apoptosis of CD40-activated human B lymphocytes

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7 January 2021

Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells.

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7 January 2021

Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis

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7 January 2021

Expression and function of Fas antigen on activated murine B cells.

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7 January 2021

Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor.

1 reference

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7 January 2021

Direct evidence that human follicular dendritic cells (FDC) rescue germinal centre B cells from death by apoptosis

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7 January 2021

A subset of anti-CD21 antibodies promote the rescue of germinal center B cells from apoptosis

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7 January 2021

Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen.

1 reference

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7 January 2021

C3d of complement as a molecular adjuvant: bridging innate and acquired immunity

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7 January 2021

Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses

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7 January 2021

Molecular analysis of original antigenic sin. I. Clonal selection, somatic mutation, and isotype switching during a memory B cell response

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7 January 2021

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Identifiers

DOI

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30 September 2017

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