(Q41431590)

English

Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene

scientific article published on November 1994

In more languages

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene (English)

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

phosphorylation

1 reference

based on heuristic

inferred from title

Human T-lymphotropic virus 1

1 reference

based on heuristic

inferred from title

T-cell leukemia

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Sun SC

1

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Elwood J

2

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Béraud C

3

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Greene WC

4

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

language of work or name

0 references

publication date

1 November 1994

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

14

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

11

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

7377-7384

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Differential expression of Rel family members in human T-cell leukemia virus type I-infected cells: transcriptional activation of c-rel by Tax protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359272

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Lipopolysaccharide induces phosphorylation of MAD3 and activation of c-Rel and related NF-kappa B proteins in human monocytic THP-1 cells.

1 reference

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Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

1 reference

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Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha

1 reference

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Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway

1 reference

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The c-rel protooncogene product represses NF-kappa B p65-mediated transcriptional activation of the long terminal repeat of type 1 human immunodeficiency virus

1 reference

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The NF-kappa B precursor p105 and the proto-oncogene product Bcl-3 are I kappa B molecules and control nuclear translocation of NF-kappa B

1 reference

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The trans-activator tax of human T-cell leukemia virus type 1 (HTLV-1) interacts with cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-1.

1 reference

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Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

1 reference

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Cytokine-inducible expression in endothelial cells of an I kappa B alpha-like gene is regulated by NF kappa B.

1 reference

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Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: positive regulation by members of the rel/NF-kappa B family

1 reference

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In vivo control of NF-kappa B activation by I kappa B alpha.

1 reference

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HTLV-I Tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerization

1 reference

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1 October 2017

Tax protein of human T-cell leukemia virus type I binds to the ankyrin motifs of inhibitory factor kappa B and induces nuclear translocation of transcription factor NF-kappa B proteins for transcriptional activation

1 reference

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Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs

1 reference

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Overproduction of NFKB2 (lyt-10) and c-Rel: a mechanism for HTLV-I Tax-mediated trans-activation via the NF-kappa B signalling pathway.

1 reference

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NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

1 reference

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Nucleotide sequence of v-rel: the oncogene of reticuloendotheliosis virus

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Nucleic acid sequences of the oncogene v-rel in reticuloendotheliosis virus strain T and its cellular homolog, the proto-oncogene c-rel

1 reference

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I kappa B: a specific inhibitor of the NF-kappa B transcription factor

1 reference

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Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor

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Stable expression of the tax gene of type I human T-cell leukemia virus in human T cells activates specific cellular genes involved in growth

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Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1.

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A transcriptional activator protein encoded by the x-lor region of the human T-cell leukemia virus

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Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis

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c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type I

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Regulation of human T cell leukemia virus expression

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The human T-lymphotropic virus type I tax gene can cooperate with the ras oncogene to induce neoplastic transformation of cells

1 reference

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Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro

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NF-kappa B: a family of inducible and differentially expressed enhancer-binding proteins in human T cells

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Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B

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Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1

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The inducible transcription activator NF-kappa B: regulation by distinct protein subunits

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Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B.

1 reference

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DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide

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Binding of the HTLV-I Tax1 transactivator to the inducible 21 bp enhancer is mediated by the cellular factor HEB1.

1 reference

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Type I human T cell leukemia virus tax protein transforms rat fibroblasts through the cyclic adenosine monophosphate response element binding protein/activating transcription factor pathway

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Four regulatory elements in the human c-fos promoter mediate transactivation by HTLV-1 Tax protein

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Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in the HTLV-I enhancer

1 reference

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1 reference

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The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression

1 reference

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Transcriptional activator Tax of HTLV-1 binds to the NF-kappa B precursor p105

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I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding

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p105 and p98 precursor proteins play an active role in NF-kappa B-mediated signal transduction

1 reference

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HTLV-I encoded Tax in association with NF-kappa B precursor p105 enhances nuclear localization of NF-kappa B p50 and p65 in transfected cells.

1 reference

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The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms

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1 reference

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Restricted expression of human T-cell leukemia--lymphoma virus (HTLV) in transformed human umbilical cord blood lymphocytes

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11 June 2018

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1 reference

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11 June 2018

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1 reference

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11 June 2018

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1 reference

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11 June 2018

The x gene is essential for HTLV replication.

1 reference

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11 June 2018

The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice

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11 June 2018

Structure and autoregulation of the c-rel promoter.

1 reference

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11 June 2018

The precursor of NF-kappa B p50 has I kappa B-like functions

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I kappa B gamma, a 70 kd protein identical to the C-terminal half of p110 NF-kappa B: a new member of the I kappa B family

1 reference

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11 June 2018

Ablation of transplanted HTLV-I Tax-transformed tumors in mice by antisense inhibition of NF-kappa B

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HTLV-I associated myelopathy, a new clinical entity.

1 reference

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17 June 2018

Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product.

1 reference

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3 July 2018

The transcriptionally active factors mediating the effect of the HTLV-I Tax transactivator on the IL-2R alpha kappa B enhancer include the product of the c-rel proto-oncogene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359272

19 August 2018

Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359272

19 August 2018

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=359272

19 August 2018

Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs

1 reference

https://pubmed.ncbi.nlm.nih.gov/7935451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the interleukin-2 receptor alpha gene: regulatory role for DNA-protein interactions flanking the kappa B enhancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/7935451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chymotryptic-type protease inhibitors block the increase in Ca2+ and Il-2 production in activated Jurkat T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7935451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.14.11.7377

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

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