(Q41441663)

30 September 2017

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title

Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family (English)

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30 September 2017

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Hoekstra MF

1

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30 September 2017

publication date

1 April 1997

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Current Opinion in Genetics & Development

30 September 2017

published in

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30 September 2017

volume

7

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30 September 2017

issue

2

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30 September 2017

page(s)

170-175

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The cellular responses to DNA damage

30 September 2017

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RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex

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Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

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Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

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Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation

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cAMP- and rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells

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Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

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7 January 2021

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

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Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.

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V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors

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7 January 2021

Strange bedfellows in even stranger places: the role of ATM in meiotic cells, lymphocytes, tumors, and its functional links to p53.

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7 January 2021

The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.

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7 January 2021

The product of the ATM gene is a 370-kDa nuclear phosphoprotein

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7 January 2021

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

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7 January 2021

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7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

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7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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7 January 2021

Isolation and characterization of the Schizosaccharomyces pombe rad3 gene, involved in the DNA damage and DNA synthesis checkpoints

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7 January 2021

An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae

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7 January 2021

The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene

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7 January 2021

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7 January 2021

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Identifiers

DOI

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30 September 2017

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