(Q41451362)

30 September 2017

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title

The matrix metalloproteinases and their inhibitors in pancreatic cancer. From molecular science to a clinical application (English)

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30 September 2017

Bramhall SR

1

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30 September 2017

publication date

1 February 1997

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International Journal of Pancreatology

30 September 2017

published in

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30 September 2017

volume

21

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30 September 2017

issue

1

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30 September 2017

page(s)

1-12

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Immunohistochemical study of heparan sulfate proteoglycan in adenocarcinomas of the pancreas.

30 September 2017

cites work

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12 December 2020

Prevention of metastasis by inhibition of the urokinase receptor

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12 December 2020

Tumour basement membrane laminin in adenocarcinoma of rectum: an immunohistochemical study of biological and clinical significance

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12 December 2020

Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors.

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12 December 2020

Matrix Metalloproteinase Matrilysin Is Constitutively Expressed in Adult Human Exocrine Epithelium

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12 December 2020

The role of the matrix metalloproteinase stromelysin in the progression of squamous cell carcinomas

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12 December 2020

Independent regulation of collagenase, 72-kDa progelatinase, and metalloendoproteinase inhibitor expression in human fibroblasts by transforming growth factor-beta

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12 December 2020

Tumor cell surface-associated binding site for the M(r) 72,000 type IV collagenase

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12 December 2020

Distribution of extracellular matrix proteins in pancreatic ductal adenocarcinoma and its influence on tumor cell proliferation in vitro.

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12 December 2020

Human skin fibroblast collagenase: interaction with substrate and inhibitor

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12 December 2020

Purification and characterization of two related but distinct metalloproteinase inhibitors secreted by bovine aortic endothelial cells.

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12 December 2020

Evidence that human rheumatoid synovial matrix metalloproteinase 3 is an endogenous activator of procollagenase

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12 December 2020

Mr 92,000 gelatinase release correlates with the metastatic phenotype in transformed rat embryo cells

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12 December 2020

Inhibition of collagenolytic activity and metastasis of tumor cells by a recombinant human tissue inhibitor of metalloproteinases

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12 December 2020

Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2

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12 December 2020

Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma

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12 December 2020

Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas

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12 December 2020

Expression of metalloproteinases and their inhibitors in primary pulmonary carcinomas

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12 December 2020

Gelatinases of murine metastatic tumor cells

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12 December 2020

A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts

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12 December 2020

cDNA sequence and mRNA tissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment

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12 December 2020

Localization of messenger RNA for Mr 72,000 and 92,000 type IV collagenases in human skin cancers by in situ hybridization

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12 December 2020

Correlation between collagenolytic activity and grade of histological differentiation in colorectal tumors

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12 December 2020

Purification and characterization of a collagenase extracted from rabbit tumours

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12 December 2020

Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes

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12 December 2020

Tissue-type plasminogen activator, a new prognostic marker in breast cancer

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12 December 2020

The spread and prognosis of carcinoma in the region of the pancreatic head

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12 December 2020

Tumor Cell Invasion Inhibited by TIMP-2

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12 December 2020

Inhibition of organ invasion by the matrix metalloproteinase inhibitor batimastat (BB-94) in two human colon carcinoma metastasis models

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12 December 2020

Regulation of matrix metalloproteinases - their role in tumor invasion and metastasis

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12 December 2020

Human alveolar macrophages produce a fibroblast-like collagenase and collagenase inhibitor

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12 December 2020

Tissue cooperation in a proteolytic cascade activating human interstitial collagenase

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12 December 2020

A matrix metalloproteinase expressed on the surface of invasive tumour cells

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12 December 2020

Expression of collagenase-related metalloproteinase genes in human lung or head and neck tumours

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12 December 2020

Inhibition of autoproteolytic activation of interstitial procollagenase by recombinant metalloproteinase inhibitor MI/TIMP-2

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12 December 2020

Distribution of collagenase and tissue inhibitor of metalloproteinases (TIMP) in colorectal tumours

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12 December 2020

Immune modulation of metalloproteinase production in human macrophages. Selective pretranslational suppression of interstitial collagenase and stromelysin biosynthesis by interferon-gamma

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12 December 2020

Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family

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12 December 2020

Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer.

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12 December 2020

Correlation between spontaneous metastatic potential and type I collagenolytic activity in a human pancreatic cancer cell line (SUIT-2) and sublines

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12 December 2020

Stromelysin/transin and tumor progression.

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12 December 2020

Over-expression of tissue inhibitor of matrix metalloproteinases (TIMP1 and TIMP2) suppresses extravasation of pulmonary metastasis of a rat bladder carcinoma

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12 December 2020

Metalloproteinases and their inhibitors in matrix remodeling

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12 December 2020

Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity

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12 December 2020

Biosynthesis of tissue inhibitor of metalloproteinases by human fibroblasts in culture. Stimulation by 12-O-tetradecanoylphorbol 13-acetate and interleukin 1 in parallel with collagenase

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12 December 2020

Extraction of type-IV collagenase/gelatinase from plasma membranes of human cancer cells

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12 December 2020

Serum metalloproteinases and their inhibitors: markers for malignant potential

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12 December 2020

Induction and stimulation of 92-kDa gelatinase/type IV collagenase production in osteosarcoma and fibrosarcoma cell lines by tumor necrosis factor alpha.

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12 December 2020

Extraction of type IV collagenase/gelatinase from plasma membranes of human pancreatic cancer cells

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12 December 2020

In vivo paracrine interaction between urokinase and its receptor: effect on tumor cell invasion

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12 December 2020

Treatment and survival in 13560 patients with pancreatic cancer, and incidence of the disease, in the West Midlands: An epidemiological study

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12 December 2020

Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin

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12 December 2020

Rabbit bone collagenase inhibitor blocks the activity of other neutral metalloproteinases

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12 December 2020

Collagenase ? A marker enzyme in human bladder cancer?

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12 December 2020

Stromelysin-3 gene expression in human cancer: an overview

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12 December 2020

The tissue metalloproteinase family and the inhibitor TIMP: a study using cDNAs and recombinant proteins

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12 December 2020

Evaluation of basement membrane components and the 72 kDa type IV collagenase in serous tumors of the ovary

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12 December 2020

Growth-promoting activity of tissue inhibitor of metalloproteinases-1 (TIMP-1) for a wide range of cells. A possible new growth factor in serum

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12 December 2020

Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells

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12 December 2020

Effect of matrix metalloproteinase inhibitor batimastat on breast cancer regrowth and metastasis in athymic mice

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12 December 2020

Diversity of human pancreatic cancer cell proteinases: role of cell membrane metalloproteinases in collagenolysis and cytolysis

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12 December 2020

The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases

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12 December 2020

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

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12 December 2020

Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues

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12 December 2020

Control of lymphatic and hematogenous metastasis of a rat mammary carcinoma by the matrix metalloproteinase inhibitor batimastat (BB-94)

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12 December 2020

Decreased expression of tissue inhibitor of metalloproteinases in metastatic tumor cells leading to increased levels of collagenase activity

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12 December 2020

Inhibition by human recombinant tissue inhibitor of metalloproteinases of human amnion invasion and lung colonization by murine B16-F10 melanoma cells

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12 December 2020

Human skin fibroblast collagenase inhibitor. Comparative studies in human connective tissues, serum, and amniotic fluid.

1 reference

12 December 2020

Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma

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12 December 2020

Localization by in situ hybridization of mRNAs encoding stromelysin 3 and tissue inhibitors of metallo-proteinases TIMP-1 and TIMP-2 in human head and neck carcinomas

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12 December 2020

Hydrolytic inactivation of a breast carcinoma cell-derived serpin by human stromelysin-3

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12 December 2020

Distribution of type IV collagen in pancreatic adenocarcinoma and chronic pancreatitis

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12 December 2020

Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT 1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties

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12 December 2020

Immunohistochemical detection of laminin in 98 human breast carcinomas: a light and electron microscopic study

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12 December 2020

Structure and expression in breast tumors of human TIMP-3, a new member of the metalloproteinase inhibitor family

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12 December 2020

The architecture of cancer

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12 December 2020

Increased stromelysin 3 gene expression is associated with increased local invasiveness in head and neck squamous cell carcinomas

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12 December 2020

Gelatinases of metastatic cell lines of murine colonic carcinoma as detected by substrate-gel electrophoresis

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12 December 2020

Tumor invasion and metastasis: an imbalance of positive and negative regulation.

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12 December 2020

Expression pattern of metalloproteinases and their inhibitors changes with the progression of human sporadic colorectal neoplasia

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12 December 2020

Molecular aspects of the metastatic cascade

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12 December 2020

Enrichment of collagen and gelatin degrading activities in the plasma membranes of human cancer cells

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12 December 2020

Tissue inhibitor of metalloproteinase (TIMP-2). A new member of the metalloproteinase inhibitor family

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12 December 2020

Type IV collagenases in tumor invasion and metastasis

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12 December 2020

Metastatic potential correlates with enzymatic degradation of basement membrane collagen

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12 December 2020

Inhibition of Angiogenesis and Murine Hemangioma Growth by Batimastat, a Synthetic Inhibitor of Matrix Metalloproteinases

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12 December 2020

A clinicopathologic study on neural invasion in cancer of the pancreatic head

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12 December 2020

The basement membrane in pathology.

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12 December 2020

Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue

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12 December 2020

Purification of rabbit bone inhibitor of collagenase

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12 December 2020

SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages

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12 December 2020

Identification of a metalloproteinase co-purifying with rat tumour collagenase and the characteristics of fragments of both enzymes

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12 December 2020

Expression of collagenase (MMP2), stromelysin (MMP3) and tissue inhibitor of the metalloproteinases (TIMP1) in pancreatic and ampullary disease

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12 December 2020

Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia

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12 December 2020

Identifiers

DOI

10.1007/BF02785914

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