(Q41465520)

1 October 2017

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title

On the front lines: intraepithelial lymphocytes as primary effectors of intestinal immunity (English)

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1 October 2017

Lefrançois L

1

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1 October 2017

Fuller B

2

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1 October 2017

Huleatt JW

3

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1 October 2017

Olson S

4

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1 October 2017

Puddington L

5

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1 October 2017

1 January 1997

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Seminars in Immunopathology

1 October 2017

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1 October 2017

18

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1 October 2017

4

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1 October 2017

463-475

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https://scigraph.springernature.com/pub.10.1007/bf00824053

1 October 2017

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12 December 2020

A major fraction of human intraepithelial lymphocytes simultaneously expresses the γ/δ T cell receptor, the CD8 accessory molecule and preferentially uses the Vδ1 gene segment

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12 December 2020

T-cell development and selection in the intestinal epithelium

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12 December 2020

Evidence that CD4+, but not CD8+ T cells are responsible for murine interleukin‐2‐deficient colitis

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12 December 2020

T lymphocytes in human gut epithelium preferentially express the alpha/beta antigen receptor and are often CD45/UCHL1-positive

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12 December 2020

Extrathymic intestinal T-cell development: virtual reality?

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12 December 2020

Expression of Murine CD1 on Gastrointestinal Epithelium

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12 December 2020

Most gamma delta T cells develop normally in beta 2-microglobulin-deficient mice

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12 December 2020

Nonpeptide ligands for human gamma delta T cells

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12 December 2020

TAP-independent, beta 2-microglobulin-dependent surface expression of functional mouse CD1.1.

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12 December 2020

Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

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12 December 2020

New member of the winged-helix protein family disrupted in mouse and rat nude mutations

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12 December 2020

Intra-epithelial lymphocytes. Evidence for regional specialization and extrathymic T cell maturation in the human gut epithelium

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12 December 2020

Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice

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12 December 2020

Inefficient positive selection of T cells directed by haematopoietic cells

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12 December 2020

Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo

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12 December 2020

Immunoregulatory functions for murine intraepithelial lymphocytes: gamma/delta T cell receptor-positive (TCR+) T cells abrogate oral tolerance, while alpha/beta TCR+ T cells provide B cell help

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12 December 2020

Adhesion molecules intercellular adhesion molecule-1 (ICAM-1), ICAM-3 and B7 are not expressed by epithelium in normal or inflamed colon

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12 December 2020

Expression of a nonpolymorphic MHC class I-like molecule, CD1D, by human intestinal epithelial cells

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12 December 2020

Definition of a lamina propria T cell responsive state. Enhanced cytokine responsiveness of T cells stimulated through the CD2 pathway.

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12 December 2020

Class II MHC antigen (Ia)-bearing dendritic cells in the epithelium of the rat intestine

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12 December 2020

Regional specialization of intraepithelial T cells in the murine small and large intestine

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12 December 2020

Extrathymic selection of TCR gamma delta + T cells by class II major histocompatibility complex molecules

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12 December 2020

Heterogeneity and biased T cell receptor alpha/beta repertoire of mucosal CD8+ cells from murine large intestine: implications for functional state

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12 December 2020

Recognition of a lipid antigen by CD1-restricted alpha beta+ T cells.

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12 December 2020

Mouse T lymphocytes that express a gamma delta T-cell antigen receptor contribute to resistance to Salmonella infection in vivo

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12 December 2020

Regional specialization of the mucosal immune system. Intraepithelial lymphocytes of the large intestine have a different phenotype and function than those of the small intestine.

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12 December 2020

A novel pathway of thymus-directed T lymphocyte maturation.

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12 December 2020

Influence of beta 2-microglobulin expression on gamma interferon secretion and target cell lysis by intraepithelial lymphocytes during intestinal Listeria monocytogenes infection

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12 December 2020

Localization of gamma/delta T cells to the intestinal epithelium is independent of normal microbial colonization

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12 December 2020

Requirement for extrathymic class I histocompatibility antigens for positive selection of thymus-derived T lymphocytes.

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12 December 2020

Differential peripheral expansion and in vivo antigen reactivity of alpha/beta and gamma/delta T cells emigrating from the early fetal lamb thymus

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12 December 2020

Thymus influences the development of extrathymically derived intestinal intraepithelial lymphocytes

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12 December 2020

Relationship between alpha/beta T cell receptor/CD8+ precursors for cytotoxic T lymphocytes in the murine Peyer's patches and the intraepithelial compartment probed by oral infection with reovirus

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12 December 2020

Thymic origin of embryonic intestinal gamma/delta T cells

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12 December 2020

Thymus-neuroendocrine interactions in extrathymic T cell development

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12 December 2020

Intraepithelial lymphocytes in human gut have lytic potential and a cytokine profile that suggest T helper 1 and cytotoxic functions

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12 December 2020

Chronic intestinal inflammation: an unexpected outcome in cytokine or T cell receptor mutant mice

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12 December 2020

Intraepithelial lymphocytes. Anatomical site, not T cell receptor form, dictates phenotype and function

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12 December 2020

Intraepithelial lymphocytes contain virus-specific, MHC-restricted cytotoxic cell precursors after gut mucosal immunization with reovirus serotype 1/Lang

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12 December 2020

Phenotype of intraepithelial lymphocytes in euthymic and athymic mice: implications for differentiation of cells bearing a CD3-associated gamma delta T cell receptor

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12 December 2020

Toxoplasma gondii oral infection induces specific cytotoxic CD8 alpha/beta+ Thy-1+ gut intraepithelial lymphocytes, lytic for parasite-infected enterocytes.

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12 December 2020

Cytokine synthesis and apoptosis by intestinal intraepithelial lymphocytes: signaling of high density alpha beta T cell receptor+ and gamma delta T cell receptor+ T cells via T cell receptor-CD3 complex results in interferon-gamma and interleukin-5

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12 December 2020

Interleukin-10-deficient mice develop chronic enterocolitis

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12 December 2020

gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses

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12 December 2020

The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats

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12 December 2020

Cytotoxic and interferon gamma-producing activities of gamma delta T cells in the mouse intestinal epithelium are strain dependent

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12 December 2020

MHC class II expression by the gut epithelium

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12 December 2020

Human intestinal intraepithelial lymphocytes have potent chemotactic activity

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12 December 2020

Human intestinal epithelial cell-induced CD8+ T cell activation is mediated through CD8 and the activation of CD8-associated p56lck

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12 December 2020

Homeostatic regulation of intestinal epithelia by intraepithelial gamma delta T cells

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12 December 2020

Differential function of intestinal intraepithelial lymphocyte subsets

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12 December 2020

T cell receptor-triggered activation of intraepithelial lymphocytes in vitro

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12 December 2020

T cells in inductive and effector compartments of the intestinal mucosal immune system of nonhuman primates differ in lymphokine mRNA expression, lymphokine utilization, and regulatory function

1 reference

12 December 2020

Beta2 integrins and ICAM-1 are involved in establishment of the intestinal mucosal T cell compartment

1 reference

12 December 2020

Evidence for function of Ia molecules on gut epithelial cells in man.

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12 December 2020

Intraepithelial lymphocytes of the intestinal mucosa: curiouser and curiouser

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12 December 2020

The nature of major histocompatibility complex recognition by gamma delta T cells.

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12 December 2020

Early appearance of "natural" mucosal IgA responses and germinal centers in suckling mice developing in the absence of maternal antibodies

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12 December 2020

Developmental relationship between cytotoxic alpha/beta T cell receptor-positive intraepithelial lymphocytes and Peyer's patch lymphocytes.

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12 December 2020

Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation

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12 December 2020

Cytolytic activity of intestinal intraepithelial lymphocytes in germ-free mice is strain dependent and determined by T cells expressing gamma delta T-cell antigen receptors

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12 December 2020

Differences in intraepithelial lymphocyte T cell subsets isolated from murine small versus large intestine

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12 December 2020

Phenotypic complexity of intraepithelial lymphocytes of the small intestine

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12 December 2020

The V beta repertoire of mouse gut homodimeric alpha CD8+ intraepithelial T cell receptor alpha/beta + lymphocytes reveals a major extrathymic pathway of T cell differentiation

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12 December 2020

Natural and synthetic non-peptide antigens recognized by human gamma delta T cells.

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12 December 2020

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

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12 December 2020

Rotavirus-specific cytotoxic T lymphocytes appear at the intestinal mucosal surface after rotavirus infection

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12 December 2020

Epithelial stem cells in vivo

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12 December 2020

Lymphocyte homing and homeostasis

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12 December 2020

Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T-cell activation

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12 December 2020

Chemokine expression by intraepithelial gamma delta T cells. Implications for the recruitment of inflammatory cells to damaged epithelia

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12 December 2020

Differential regulation of B7 mRNA in enterocytes and lymphoid cells

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12 December 2020

Modulation of epithelial cell growth by intraepithelial gamma delta T cells

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12 December 2020

Diversity, development, ligands, and probable functions of gamma delta T cells.

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12 December 2020

In vivo modulation of cytolytic activity and Thy-1 expression in TCR-gamma delta+ intraepithelial lymphocytes

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12 December 2020

Identifiers

DOI

10.1007/BF00824053

1 reference

1 October 2017

1 reference