(Q41493319)

1 October 2017

1 reference

title

Glutamate, excitotoxicity and amyotrophic lateral sclerosis (English)

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amyotrophic lateral sclerosis

1 October 2017

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1 reference

P J Shaw

1

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PubMed ID

9178165

1 October 2017

P G Ince

series ordinal

2

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1 October 2017

1 May 1997

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1 October 2017

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1 October 2017

244 Suppl 2

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1 October 2017

S3-14

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https://scigraph.springernature.com/pub.10.1007/bf03160574

1 October 2017

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cites work

Glutamate or aspartate as a possible neurotransmitter of cerebral corticofugal fibers in the monkey

1 reference

https://api.crossref.org/works/10.1007%2FBF03160574

Brain glutamate deficiency in amyotrophic lateral sclerosis.

21 January 2018

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The central nervous system in a cast? of neurolathyrism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03160574

2-Amino-3-(methylamino)-propanoic acid (BMAA) in cycad flour: an unlikely cause of amyotrophic lateral sclerosis and parkinsonism-dementia of Guam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03160574

Antagonism by riluzole of entry of calcium evoked by NMDA and veratridine in rat cultured granule cells: evidence for a dual mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03160574

Pertussis toxin pretreatment abolishes the inhibitory effect of riluzole and carbachol on D-[3H]aspartate release from cultured cerebellar granule cells

21 January 2018

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12 December 2020

Serum antibodies to L-type calcium channels in patients with amyotrophic lateral sclerosis

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12 December 2020

An immunocytochemical study of the distribution of AMPA selective glutamate receptor subunits in the normal human motor system.

1 reference

12 December 2020

Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

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12 December 2020

A family of AMPA-selective glutamate receptors

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12 December 2020

Assessment of reliability and biological significance of glutamate levels in cerebrospinal fluid

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12 December 2020

Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA

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12 December 2020

Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis

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12 December 2020

Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures

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12 December 2020

Free radicals and the pathogenesis of neuronal death: cooperative role of excitatory amino acids

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12 December 2020

Glutamate receptor channels: novel properties and new clones

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12 December 2020

Motor neuron degeneration induced by excitotoxin agonists has features in common with those seen in the SOD-1 transgenic mouse model of amyotrophic lateral sclerosis

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12 December 2020

Non-NMDA receptors in motor neuron disease (MND): a quantitative autoradiographic study in spinal cord and motor cortex using [3H]CNQX and [3H]kainate

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12 December 2020

Oxidative stress, glutamate, and neurodegenerative disorders

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12 December 2020

Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice

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12 December 2020

Contributory mechanisms in the causation of neurodegenerative disorders

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12 December 2020

Neuronal Ca2+ channels and their regulation by excitatory amino acids

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12 December 2020

Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity

1 reference

12 December 2020

A family of glutamate receptor genes: evidence for the formation of heteromultimeric receptors with distinct channel properties

1 reference

12 December 2020

Are NMDA or AMPA/kainate receptor antagonists more efficacious in the delayed treatment of excitotoxic neuronal injury?

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12 December 2020

The toxic effect of sodium L-glutamate on the inner layers of the retina.

1 reference

12 December 2020

Abnormal distribution of phosphorylated neurofilaments in neuronal degeneration induced by kainic acid

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12 December 2020

Oxidative damage to protein in sporadic motor neuron disease spinal cord

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12 December 2020

Ionic dependence of glutamate neurotoxicity

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12 December 2020

Randomized, double-blind, controlled trial of acetylcysteine in amyotrophic lateral sclerosis

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12 December 2020

Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain

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12 December 2020

Iron, selenium and glutathione peroxidase activity are elevated in sporadic motor neuron disease

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12 December 2020

An outbreak of toxic encephalopathy caused by eating mussels contaminated with domoic acid.

1 reference

12 December 2020

Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced

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12 December 2020

Riluzole specifically blocks inactivated Na channels in myelinated nerve fibre

1 reference

12 December 2020

The neuroexcitotoxic amino acids glutamate and aspartate are altered in the spinal cord and brain in amyotrophic lateral sclerosis

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12 December 2020

Inactivation of mammalian brain glutamine synthetase by oxygen radicals

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12 December 2020

Autoradiographic distribution of binding sites for the non-NMDA receptor antagonist [3H]CNQX in human motor cortex, brainstem and spinal cord

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12 December 2020

Riluzole, a novel antiglutamate, prevents memory loss and hippocampal neuronal damage in ischemic gerbils.

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12 December 2020

Neutron Activation Analysis of Trace Elements in Motor Neuron Disease Spinal Cord

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12 December 2020

Block of the rat brain IIA sodium channel alpha subunit by the neuroprotective drug riluzole.

1 reference

12 December 2020

Excitotoxicity and motor neurone disease: a review of the evidence

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12 December 2020

Reactive oxygen species and the central nervous system

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12 December 2020

Amyotrophic lateral sclerosis: amino acid levels in plasma and cerebrospinal fluid

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12 December 2020

Lathyrism: evidence for role of the neuroexcitatory aminoacid BOAA.

1 reference

12 December 2020

Reductions in acidic amino acids andN-acetylaspartylglutamate in amyotrophic lateral sclerosis CNS

1 reference

12 December 2020

Cortical excitability in amyotrophic lateral sclerosis: a clue to pathogenesis.

1 reference

12 December 2020

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Metallothionein in amyotrophic lateral sclerosis

1 reference

12 December 2020

CSF and plasma amino acid levels in motor neuron disease: elevation of CSF glutamate in a subset of patients.

1 reference

12 December 2020

Primary structure and functional characterization of a high-affinity glutamate transporter

1 reference

12 December 2020

Neuroprotective strategies in a model of chronic glutamate-mediated motor neuron toxicity

1 reference

12 December 2020

Cloning of a putative high-affinity kainate receptor expressed predominantly in hippocampal CA3 cells

1 reference

12 December 2020

Glutamine from glial cells is essential for the maintenance of the nerve terminal pool of glutamate: immunogold evidence from hippocampal slice cultures

1 reference

12 December 2020

Metals in spinal cord tissue of patients dying of motor neuron disease

1 reference

12 December 2020

The quantitative autoradiographic distribution of [3H]MK-801 binding sites in the normal human spinal cord

1 reference

12 December 2020

Glutamate receptor update

1 reference

12 December 2020

Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis

1 reference

12 December 2020

A role for Na+-dependent Ca2+ extrusion in protection against neuronal excitotoxicity

1 reference

12 December 2020

Human neurolathyrism, a follow-up study of 200 patients. Part I: Clinical investigation

1 reference

12 December 2020

Failure of neuronal ion exchange, not potentiated excitation, causes excitotoxicity after inhibition of oxidative phosphorylation

1 reference

12 December 2020

Desensitization of AMPA receptors limits the amplitude of EPSPs and the excitability of motoneurons of the rat isolated spinal cord.

1 reference

12 December 2020

AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity

1 reference

12 December 2020

Motor neuron disease. Studies of the corticospinal excitation of single motor neurons by magnetic brain stimulation

1 reference

12 December 2020

Review: neurotransmitter receptors. II. AMPA and kainate receptors

1 reference

12 December 2020

Glutamate transporter gene expression in amyotrophic lateral sclerosis motor cortex

1 reference

12 December 2020

Anterior horn cell changes in a case of neurolathyrism

1 reference

12 December 2020

Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin

1 reference

12 December 2020

Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis

1 reference

12 December 2020

Prolonged infusion of quinolinic acid into rat striatum as an excitotoxic model of neurodegenerative disease

1 reference

12 December 2020

Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor

1 reference

12 December 2020

Immunocytochemical study of the distribution of the free radical scavenging enzymes CU/ZN superoxide dismutase (SOD1); MN superoxide dismutase (MN SOD) and catalase in the normal human spinal cord and in motor neuron disease

1 reference

12 December 2020

Cloning and expression of a rat brain L-glutamate transporter

1 reference

12 December 2020

Oxidative processes and antioxidative defense mechanisms in the aging brain

1 reference

12 December 2020

Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II

1 reference

12 December 2020

Excitatory amino acid receptor activation produces a selective and long-lasting modulation of gene expression in hippocampal neurons

1 reference

12 December 2020

Glutamate neurotoxicity and diseases of the nervous system

1 reference

12 December 2020

Excitatory amino acid neurotoxicity and neurodegenerative disease

1 reference

12 December 2020

The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits.

1 reference

12 December 2020

N-methyl-D-aspartate (NMDA) receptors in the spinal cord and motor cortex in motor neuron disease: a quantitative autoradiographic study using [3H]MK-801.

1 reference

12 December 2020

Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Copper/zinc superoxide dismutase mRNA levels are increased in sporadic amyotrophic lateral sclerosis motorneurons

1 reference

12 December 2020

Cloning of a putative glutamate receptor: a low affinity kainate-binding subunit

1 reference

12 December 2020

Cell culture evidence for neuronal degeneration in amyotrophic lateral sclerosis being linked to glutamate AMPA/kainate receptors

1 reference

12 December 2020

Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis

1 reference

12 December 2020

Excitotoxic mechanisms in the pathogenesis of amyotrophic lateral sclerosis.

1 reference

12 December 2020

Evidence for autoimmunity in amyotrophic lateral sclerosis

1 reference

12 December 2020

Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)

1 reference

12 December 2020

Nuclear and cell body size in spinal motor neurons

1 reference

12 December 2020

Cortical function in amyotrophic lateral sclerosis. A positron emission tomography study.

1 reference

12 December 2020

Identification of a site in glutamate receptor subunits that controls calcium permeability

1 reference

12 December 2020

Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines

1 reference

12 December 2020

An excitatory amino-acid transporter with properties of a ligand-gated chloride channel

1 reference

12 December 2020

A radical hypothesis for neurodegeneration

1 reference

12 December 2020

Plasma amino acid levels in patients with amyotrophic lateral sclerosis

1 reference

12 December 2020

Neuronal intermediate filaments

1 reference

12 December 2020

1 reference

12 December 2020

Localization of neuronal and glial glutamate transporters

1 reference

12 December 2020

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

1 reference

12 December 2020

Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit

1 reference

12 December 2020

Prolonged exposure to submicromolar concentrations of quinolinic acid causes excitotoxic damage in organotypic cultures of rat corticostriatal system

1 reference

12 December 2020

Excitotoxicity in the embryonic chick spinal cord

1 reference

12 December 2020

Lathyrism and western Pacific amyotrophic lateral sclerosis: etiology of short and long latency motor system disorders

1 reference

12 December 2020

Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes.

1 reference

12 December 2020

Cloned glutamate receptors

1 reference

12 December 2020

Cloning, expression and modulation of a mouse NMDA receptor subunit

1 reference

12 December 2020

Excitatory amino acids, free radicals and the pathogenesis of motor neuron disease

1 reference

12 December 2020

Historical overview. Calcium, ischemia, and death of brain cells

1 reference

12 December 2020

Molecular diversity of the NMDA receptor channel

1 reference

12 December 2020

Role of excitotoxicity in human neurological disease

1 reference

12 December 2020

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

12 December 2020

Abnormal glutamate metabolism in amyotrophic lateral sclerosis.

1 reference

12 December 2020

[3H]d-aspartate binding sites in the normal human spinal cord and changes in motor neuron disease: a quantitative autoradiographic study

1 reference

12 December 2020

A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group

1 reference

12 December 2020

An [Na+ + K+]coupled L-glutamate transporter purified from rat brain is located in glial cell processes.

1 reference

12 December 2020

Parvalbumin and calbindin D-28k in the human motor system and in motor neuron disease.

1 reference

12 December 2020

The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system

1 reference

12 December 2020

Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes

1 reference

12 December 2020

Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs

1 reference

12 December 2020

Neuroprotective effects of riluzole on N-methyl-D-aspartate- or veratridine-induced neurotoxicity in rat hippocampal slices

1 reference

12 December 2020

Molecular cloning and functional expression of glutamate receptor subunit genes

1 reference

12 December 2020

Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS

1 reference

12 December 2020

Modulation of embryonic chick motoneuron glutamate sensitivity by interneurons and agonists.

1 reference

12 December 2020

Neurologic sequelae of domoic acid intoxication due to the ingestion of contaminated mussels.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF03160574

1 reference

1 October 2017

1 reference

PubMed ID

9178165