(Q41500830)

1 October 2017

1 reference

title

Nucleosome-driven autoimmune response in lupus. Pathogenic T helper cell epitopes and costimulatory signals (English)

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1 October 2017

Datta SK

1

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1 October 2017

Kaliyaperumal A

series ordinal

2

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1 October 2017

language of work or name

English

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publication date

1 April 1997

1 reference

Annals of the New York Academy of Sciences

1 October 2017

published in

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1 October 2017

volume

815

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1 October 2017

page(s)

155-170

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VH-gene representation in autoantibodies reflects the normal human B-cell repertoire

1 October 2017

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The viral envelope glycoprotein of murine leukemia virus and the pathogenesis of immune complex glomerulonephritis of New Zealand mice

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Lack of relationship between serum gp70 levels and the severity of systemic lupus erythematosus in MRL/l mice

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Susceptibility to lymphomas and expression of C-type RNA viruses during the graft versus host reaction

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Recovery of xenotropic virus but not ecotropic virus during graft-versus-host reaction in mice

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A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen

21 January 2018

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Anti-idiotypic antibodies to the Coombs antibody in NZB F1 mice

21 January 2018

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Cellular aspects of the inverse relationship between the net charge of immunogens of antibodies elicited

21 January 2018

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Induction of a cationic shift in IgG anti-DNA autoantibodies. Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis

21 January 2018

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Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB x NZW)F1 mice

21 January 2018

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Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation

21 January 2018

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Histones have high affinity for the glomerular basement membrane. Relevance for immune complex formation in lupus nephritis

21 January 2018

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Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus

21 January 2018

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T-cell-receptor beta- and I-A beta-chain genes of normal SWR mice are linked with the development of lupus nephritis in NZB x SWR crosses

21 January 2018

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Junctional region sequences of T-cell receptor beta-chain genes expressed by pathogenic anti-DNA autoantibody-inducing helper T cells from lupus mice: possible selection by cationic autoantigens

21 January 2018

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Imprint of thymic selection on autoreactive repertoires

21 January 2018

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Pathogenic anti-DNA autoantibody-inducing T helper cell lines from patients with active lupus nephritis: isolation of CD4-8- T helper cell lines that express the gamma delta T-cell antigen receptor

21 January 2018

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Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenics

21 January 2018

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The Relation of Immunoglobulin Class, Pattern of Antinuclear Antibody, and Complement-Fixing Antibodies to DNA in Sera from Patients with Systemic Lupus Erythematosus*

21 January 2018

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Rearrangement of the histone H2A C-terminal domain in the nucleosome

21 January 2018

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21 January 2018

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Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupus

21 January 2018

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Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B'-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity

21 January 2018

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In vivo expression of a single viral DNA-binding protein generates systemic lupus erythematosus-related autoimmunity to double-stranded DNA and histones

21 January 2018

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Systemic lupus erythematosus: emerging concepts. Part 1: Renal, neuropsychiatric, cardiovascular, pulmonary, and hematologic disease

21 January 2018

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Pathogenic autoantibody-inducing gamma/delta T helper cells from patients with lupus nephritis express unusual T cell receptors

21 January 2018

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Heterogeneity of T-cell receptor alpha-chain complementarity-determining region 3 in myelin basic protein-specific T cells increases with severity of multiple sclerosis.

21 January 2018

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Very long charge runs in systemic lupus erythematosus-associated autoantigens

21 January 2018

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Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors

21 January 2018

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Regulatory Mechanisms in the Immune Response to Cell-surface Antigens

21 January 2018

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Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen

21 January 2018

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Novel autoimmune phenomena induced in vivo by a new DNA binding protein Nuc: a study on MRL/n mice.

21 January 2018

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Anti-DNA antibodies bind to DNase I.

21 January 2018

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Systemic autoimmune disease arises from polyclonal B cell activation

21 January 2018

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Development of autoimmune disease in SCID mice populated with long-term "in vitro" proliferating (NZB x NZW)F1 pre-B cells

21 January 2018

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CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation

21 January 2018

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How B and T cells talk to each other

21 January 2018

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Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion

21 January 2018

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Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells.

21 January 2018

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Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2

21 January 2018

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CD40 signaling pathway: anti-CD40 monoclonal antibody induces rapid dephosphorylation and phosphorylation of tyrosine-phosphorylated proteins including protein tyrosine kinase Lyn, Fyn, and Syk and the appearance of a 28-kD tyrosine phosphorylated p

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

B-cell activation by crosslinking of surface IgM or ligation of CD40 involves alternative signal pathways and results in different B-cell phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

Molecular and biological characterization of a murine ligand for CD40

21 January 2018

1 reference

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A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

Human CD40-ligand: molecular cloning, cellular distribution and regulation of expression by factors controlling IgE production

21 January 2018

1 reference

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In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

The relative contribution of the CD28 and gp39 costimulatory pathways in the clonal expansion and pathogenic acquisition of self-reactive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

In the absence of a CD40 signal, B cells are tolerogenic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

Treatment of murine lupus with CTLA4Ig

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor

21 January 2018

1 reference

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Th2 cell clonal anergy as a consequence of partial activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

Initiation of autoimmunity to the p53 tumor suppressor protein by complexes of p53 and SV40 large T antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

Antigen-specific interaction between T and B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

Mechanism of antigen-driven selection in germinal centres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1997.TB52057.X

10.1111/J.1749-6632.1997.TB52057.X

21 January 2018

Identifiers

DOI

1 reference

1 October 2017

1 reference