(Q41502419)

English

A disease-causing point mutation in human mitochondrial tRNAMet results in tRNA misfolding leading to defects in translational initiation and elongation

scientific article published on 3 October 2008

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scholarly article

1 reference

Europe PubMed Central

1 October 2017

A disease-causing point mutation in human mitochondrial tRNAMet results in tRNA misfolding leading to defects in translational initiation and elongation (English)

1 reference

Europe PubMed Central

1 October 2017

author name string

Christie N Jones

1

1 reference

Europe PubMed Central

1 October 2017

Christopher I Jones

2

1 reference

Europe PubMed Central

1 October 2017

William D Graham

3

1 reference

Europe PubMed Central

1 October 2017

Paul F Agris

4

1 reference

Europe PubMed Central

1 October 2017

Linda L Spremulli

5

1 reference

Europe PubMed Central

1 October 2017

language of work or name

0 references

publication date

3 October 2008

1 reference

Europe PubMed Central

1 October 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

1 October 2017

283

1 reference

Europe PubMed Central

1 October 2017

34445-34456

1 reference

Europe PubMed Central

1 October 2017

49

1 reference

Europe PubMed Central

1 October 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2590712/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Complementary roles of initiation factor 1 and ribosome recycling factor in 70S ribosome splitting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590712

10 June 2018

Decreased aminoacylation in pathology-related mutants of mitochondrial tRNATyr is associated with structural perturbations in tRNA architecture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590712

10 June 2018

Pathogenic mechanism of a human mitochondrial tRNAPhe mutation associated with myoclonic epilepsy with ragged red fibers syndrome.

1 reference

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10 June 2018

Selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE): quantitative RNA structure analysis at single nucleotide resolution

1 reference

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10 June 2018

A fast-acting reagent for accurate analysis of RNA secondary and tertiary structure by SHAPE chemistry

1 reference

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A counterintuitive Mg2+-dependent and modification-assisted functional folding of mitochondrial tRNAs

1 reference

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10 June 2018

RNA structure analysis at single nucleotide resolution by selective 2'-hydroxyl acylation and primer extension (SHAPE)

1 reference

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SAFA: semi-automated footprinting analysis software for high-throughput quantification of nucleic acid footprinting experiments

1 reference

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Codon-specific translational defect caused by a wobble modification deficiency in mutant tRNA from a human mitochondrial disease

1 reference

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10 June 2018

Interaction of mitochondrial initiation factor 2 with mitochondrial fMet-tRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590712

10 June 2018

Characterization of the human mitochondrial methionyl-tRNA synthetase

1 reference

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10 June 2018

Impact of disease-related mitochondrial mutations on tRNA structure and function

1 reference

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10 June 2018

Structure of the Mammalian Mitochondrial Ribosome Reveals an Expanded Functional Role for Its Component Proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590712

10 June 2018

Human mitochondrial tRNAs in health and disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590712

10 June 2018

Decreased mitochondrial tRNALys steady-state levels and aminoacylation are associated with the pathogenic G8313A mitochondrial DNA mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2590712

10 June 2018

The pathogenic U3271C human mitochondrial tRNA(Leu(UUR)) mutation disrupts a fragile anticodon stem

1 reference

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In vitro 3'-end endonucleolytic processing defect in a human mitochondrial tRNA(Ser(UCN)) precursor with the U7445C substitution, which causes non-syndromic deafness

1 reference

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Uniform binding of aminoacyl-tRNAs to elongation factor Tu by thermodynamic compensation

1 reference

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10 June 2018

Search for characteristic structural features of mammalian mitochondrial tRNAs.

1 reference

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1 reference

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Structural and functional roles of the N1- and N3-protons of psi at tRNA's position 39

1 reference

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Mammalian mitochondrial methionyl-tRNA transformylase from bovine liver. Purification, characterization, and gene structure.

1 reference

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The first pathogenic mitochondrial methionine tRNA point mutation is discovered in splenic lymphoma

1 reference

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10 June 2018

Compilation of tRNA sequences and sequences of tRNA genes

1 reference

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A disease-associated G5703A mutation in human mitochondrial DNA causes a conformational change and a marked decrease in steady-state levels of mitochondrial tRNA(Asn).

1 reference

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10 June 2018

Structure of an RNA double helix including uracil-uracil base pairs in an internal loop

1 reference

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10 June 2018

Higher-order structure of bovine mitochondrial tRNA(SerUGA): chemical modification and computer modeling.

1 reference

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Higher-order structure of bovine mitochondrial tRNA(Phe) lacking the 'conserved' GG and T psi CG sequences as inferred by enzymatic and chemical probing.

1 reference

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10 June 2018

Complete sequence of bovine mitochondrial DNA. Conserved features of the mammalian mitochondrial genome

2 references

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Role of the 5'-terminal phosphate of tRNA for its function during protein biosynthesis elongation cycle.

1 reference

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Relative affinities of all Escherichia coli aminoacyl-tRNAs for elongation factor Tu-GTP

1 reference

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Animal mitochondrial DNA: an extreme example of genetic economy

1 reference

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Anticodon switching changes the identity of methionine and valine transfer RNAs.

1 reference

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A novel cloverleaf structure found in mammalian mitochondrial tRNA(Ser) (UCN).

1 reference

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Defects in mitochondrial protein synthesis and respiratory chain activity segregate with the tRNA(Leu(UUR)) mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes

1 reference

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1 reference

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1 reference

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Functional defects of pathogenic human mitochondrial tRNAs related to structural fragility

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A Watson-Crick base-pair-disrupting methyl group (m1A9) is sufficient for cloverleaf folding of human mitochondrial tRNALys.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/18835817

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18835817

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18835817

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18835817

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18835817

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M806992200

1 reference

Europe PubMed Central

1 October 2017

1 reference

Europe PubMed Central

1 October 2017

1 reference

Europe PubMed Central

1 October 2017

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