(Q41509732)

English

Not all G-quadruplexes are created equally: an investigation of the structural polymorphism of the c-Myc G-quadruplex-forming sequence and its interaction with the porphyrin TMPyP4

scientific article published on 29 October 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Not all G-quadruplexes are created equally: an investigation of the structural polymorphism of the c-Myc G-quadruplex-forming sequence and its interaction with the porphyrin TMPyP4 (English)

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Jonathan B. Chaires

6

0 references

author name string

Huy T Le

1

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

M Clarke Miller

2

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Robert Buscaglia

3

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

William L Dean

4

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Patrick A Holt

5

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Jonathan B Chaires

6

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

John O Trent

7

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

publication date

29 October 2012

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Organic and Biomolecular Chemistry

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

10

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

47

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

9393-9404

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

Structure and stability of higher-order human telomeric quadruplexes

1 reference

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10 June 2018

Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Polymorphism and resolution of oncogene promoter quadruplex-forming sequences.

1 reference

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10 June 2018

The insertion of two 8-methyl-2'-deoxyguanosine residues in tetramolecular quadruplex structures: trying to orientate the strands

1 reference

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10 June 2018

c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability

1 reference

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10 June 2018

Inhibition of cell proliferation by quindoline derivative (SYUIQ-05) through its preferential interaction with c-myc promoter G-quadruplex

1 reference

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10 June 2018

Targeting MYC Expression through G-Quadruplexes

1 reference

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10 June 2018

Structural insights into G-quadruplexes: towards new anticancer drugs

1 reference

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10 June 2018

Resolution and characterization of the structural polymorphism of a single quadruplex-forming sequence

1 reference

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10 June 2018

Characterization of a K+-induced conformational switch in a human telomeric DNA oligonucleotide using 2-aminopurine fluorescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Human telomeric G-quadruplex: the current status of telomeric G-quadruplexes as therapeutic targets in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Energetics and kinetics of a conformational switch in G-quadruplex DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

A G-Rich Sequence within the c-kit Oncogene Promoter Forms a Parallel G-Quadruplex Having Asymmetric G-Tetrad Dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Identification and characterization of nucleolin as a c-myc G-quadruplex-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Effect of locked-nucleic acid on a biologically active g-quadruplex. A structure-activity relationship of the thrombin aptamer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Stability and kinetics of G-quadruplex structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Four-stranded nucleic acids: structure, function and targeting of G-quadruplexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

8-Amino guanine accelerates tetramolecular G-quadruplex formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Polymorphism of human telomeric quadruplex structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Role of locked nucleic acid modified complementary strand in quadruplex/Watson-Crick duplex equilibrium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Biophysical studies of the c-MYC NHE III1 promoter: model quadruplex interactions with a cationic porphyrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

G-quadruplexes in promoters throughout the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Engineering the quadruplex fold: nucleoside conformation determines both folding topology and molecularity in guanine quadruplexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

8-methyl-2'-deoxyguanosine incorporation into parallel DNA quadruplex structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Thermal difference spectra: a specific signature for nucleic acid structures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Prevalence of quadruplexes in the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Myc pathways provoking cell suicide and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Biophysical and biological properties of quadruplex oligodeoxyribonucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

The design of G-quadruplex ligands as telomerase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

6-Thioguanine alters the structure and stability of duplex DNA and inhibits quadruplex DNA formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

MYC oncogenes and human neoplastic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Porphyrin binding to quadrupled T4G4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

DNA tetraplex formation in the control region of c-myc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Normal human chromosomes have long G-rich telomeric overhangs at one end

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

A survey of telomerase activity in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Divalent transition metal cations counteract potassium-induced quadruplex assembly of oligo(dG) sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

G-quartet structures in telomeric DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

10 June 2018

Evidence for the binding mode of porphyrins to G-quadruplex DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

19 August 2018

Effect of O6-methylguanine on the stability of G-quadruplex DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

19 August 2018

Human telomere quadruplex: refolding and selection of individual conformers via RNA/DNA chimeric editing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

19 August 2018

Gene function correlates with potential for G4 DNA formation in the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

19 August 2018

A spectroscopic study on the interactions of porphyrin with G-quadruplex DNAs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

19 August 2018

Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

19 August 2018

Solution structure of the biologically relevant G-quadruplex element in the human c-MYC promoter. Implications for G-quadruplex stabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

19 August 2018

Effects of 8-methyl-2'-deoxyadenosine incorporation into quadruplex forming oligodeoxyribonucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

19 August 2018

Theoretical study of the guanine --> 6-thioguanine substitution in duplexes, triplexes, and tetraplexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

19 August 2018

Effects of an 8-bromodeoxyguanosine incorporation on the parallel quadruplex structure [d(TGGGT)]4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501587

19 August 2018

Targeting telomeres and telomerase

1 reference

https://api.crossref.org/works/10.1039%2FC2OB26504D

21 January 2018

A new class of DNA quadruplexes formed by oligodeoxyribonucleotides containing a 3′-3′ or 5′-5′ inversion of polarity site

1 reference

https://api.crossref.org/works/10.1039%2FC2OB26504D

21 January 2018

A further contribution to the extreme variability of quadruplex structures from oligodeoxyribonucleotides containing inversion of polarity sites in the G-tract

1 reference

https://api.crossref.org/works/10.1039%2FC2OB26504D

21 January 2018

Topological Characterization of Nucleic Acid G-Quadruplexes by UV Absorption and Circular Dichroism

1 reference

https://api.crossref.org/works/10.1039%2FC2OB26504D

21 January 2018

Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes

1 reference

https://api.crossref.org/works/10.1039%2FC2OB26504D

21 January 2018

Effects of the introduction of inversion of polarity sites in the quadruplex forming oligonucleotide TGGGT

1 reference

https://api.crossref.org/works/10.1039%2FC2OB26504D

21 January 2018

The dynamic character of the G-quadruplex element in the c-MYC promoter and modification by TMPyP4

1 reference

https://pubmed.ncbi.nlm.nih.gov/23108607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human telomeric DNA forms parallel-stranded intramolecular G-quadruplex in K+ solution under molecular crowding condition

1 reference

https://pubmed.ncbi.nlm.nih.gov/23108607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quadruplex structure of polyriboinosinic acid: dependence on alkali metal ion concentration, pH and temperature

1 reference

https://pubmed.ncbi.nlm.nih.gov/23108607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural transition of d(G4T4G4) from antiparallel to parallel G-quartet induced by divalent cations

1 reference

https://pubmed.ncbi.nlm.nih.gov/23108607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydration is a major determinant of the G-quadruplex stability and conformation of the human telomere 3' sequence of d(AG3(TTAG3)3)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23108607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1039/C2OB26504D

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

1 October 2017

ResearchGate publication ID

0 references

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