(Q41545862)

English

Interrelationship between O6-alkylguanine-DNA alkyltransferase activity and susceptibility to chloroethylnitrosoureas in several glioma cell lines

scientific article published on July 1993

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

Interrelationship between O6-alkylguanine-DNA alkyltransferase activity and susceptibility to chloroethylnitrosoureas in several glioma cell lines (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

author name string

T Hotta

1

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

Y Saito

2

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

T Mikami

3

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

K Kurisu

4

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

K Kiya

5

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

T Uozumi

6

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

G Isowa

7

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

K Ishizaki

8

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

M Ikenaga

9

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 July 1993

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

Journal of Neuro-Oncology

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

17

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

1-8

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

Morphological and immunochemical studies of rat glial tumors and clonal strains propagated in culture

1 reference

https://api.crossref.org/works/10.1007%2FBF01054267

21 January 2018

O6-Methylguanine-DNA methyltransferase in human cells.

1 reference

https://api.crossref.org/works/10.1007%2FBF01054267

21 January 2018

DNA alkylation by the haloethylnitrosoureas: nature of modifications produced and their enzymatic repair or removal

1 reference

https://api.crossref.org/works/10.1007%2FBF01054267

21 January 2018

Increased O6-alkylguanine alkyltransferase activity in Chinese hamster V79 cells following selection with chloroethylating agents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antineoplastic activity of the combination of interferon and cytotoxic agents against experimental and human malignancies: a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human tumor cell strains defective in the repair of alkylation damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitrosourea chemotherapy for primary malignant gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypersensitivity of rat glioma sublines with acquired ACNU resistance to L-asparaginase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that O6-alkylguanine-DNA alkyltransferase becomes covalently bound to DNA containing 1,3-bis(2-chloroethyl)-1-nitrosourea-induced precursors of interstrand cross-links

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Removal of O6-methylguanine from DNA of normal and xeroderma pigmentosum-derived lymphoblastoid lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response of cultured human cell lines from rhabdomyosarcoma xenografts to treatment with chloroethylnitrosoureas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic and mutagenic effects of methylnitrosourea in two human fetal fibroblast strains differing in O6-methylguanine-DNA methyltransferase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regeneration of O6-alkylguanine-DNA alkyltransferase in human lymphocytes after nitrosourea exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the O6-methylguanine-DNA methyltransferase gene MGMT in MER+ and MER- human tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative analysis of O6-methylguanine methyltransferase activity and cellular sensitivity to alkylating agents in cell strains derived from a variety of animal species

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Removal of O6-methylguanine from DNA by human liver fractions

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acquisition of resistance to 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride in V79 cells through increased removal of O6-alkylguanine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of the nitrosoureas--V. Formation of O6-(2-fluoroethyl)guanine and its probable role in the crosslinking of deoxyribonucleic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of ACNU and radiotherapy on malignant glioma

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione and cellular response of ACNU-resistant rat glioma sublines to drugs and radiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of human O6-methylguanine-DNA methyltransferase in a DNA excision repair-deficient Chinese hamster ovary cell line and its response to certain alkylating agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adaptive response to alkylating agents involves alteration in situ of O6-methylguanine residues in DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Limited capacity for the removal of O6-methylguanine and its regeneration in a human lymphoma line

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of streptozotocin/bis-chloroethylnitrosourea combination therapy on O6-methylguanine DNA methyltransferase activity and mRNA levels in HT-29 cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of human fibroblast interferon with chemotherapeutic agents and radiation against human gliomas in nude mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle-dependent modulation of O6-methylguanine-DNA methyltransferase in C3H/10T1/2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-resistance patterns in ACNU-resistant glioma sublines in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simplified assay for O6-methylguanine-DNA methyltransferase activity and its application to human neoplastic and non-neoplastic tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationships among cell survival, O6-alkylguanine-DNA alkyltransferase activity, and reactivation of methylated adenovirus 5 and herpes simplex virus type 1 in human melanoma cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and purification of O6-alkylguanine-DNA alkyltransferase from human leukemic cells. Prevention of chloroethylnitrosourea-induced cross-links by purified enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypersensitivity of human tumor xenografts lacking O6-alkylguanine-DNA alkyltransferase to the anti-tumor agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitros ourea.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adaptive resynthesis of O6-methylguanine-accepting protein can explain the differences between mammalian cells proficient and deficient in methyl excision repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of induction of O6-methylguanine-DNA methyltransferase in mammalian cells treated with N-methyl-N'-nitro-N-nitrosoguanidine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of nitrosourea cytotoxicity in human leukemic cells by inactivation of O6-alkylguanine-DNA alkyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Difference in O6-methylguanine methyltransferase activity among transformed NIH3T3 cell clones

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of O6-methylguanine-DNA methyltransferase and sensitization of human tumor cells to killing by chloroethylnitrosourea by O6-methylguanine as a free base.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The O6-methylguanine-DNA-methyltransferase activity of rat hepatoma cells is increased after a single exposure to alkylating agents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tolerance to O6-methylguanine and 6-thioguanine cytotoxic effects: a cross-resistant phenotype in N-methylnitrosourea-resistant Chinese hamster ovary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro studies on potentiation of cytotoxic effects of anticancer drugs by interferon on a human neoplastic cell line (HeLa)

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic killing of virus-transformed human cells with interferon and N-methyl-N'-nitro-N-nitrosoguanidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of ACNU-resistant Rat Gliosarcoma Cell Lines and Their Characteristics

1 reference

https://pubmed.ncbi.nlm.nih.gov/8120566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF01054267

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

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0 references

release_qnpbgdus6rehhb3gvazxwzgphi

1 reference

https://api.fatcat.wiki/v0/release/qnpbgdus6rehhb3gvazxwzgphi

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 October 2017

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