(Q41554112)

3 October 2017

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title

Using structure to define the function of phosphoinositide 3-kinase family members (English)

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3 October 2017

Domin J

1

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3 October 2017

Waterfield MD

series ordinal

2

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3 October 2017

language of work or name

English

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publication date

1 June 1997

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3 October 2017

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3 October 2017

volume

410

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3 October 2017

issue

1

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3 October 2017

page(s)

91-95

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3 October 2017

cites work

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21 January 2018

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Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85

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Binding to the platelet-derived growth factor receptor transiently activates the p85alpha-p110alpha phosphoinositide 3-kinase complex in vivo

21 January 2018

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Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

21 January 2018

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Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain

21 January 2018

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The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase

21 January 2018

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A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity

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A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

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The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

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Regulation of phosphatidylinositol 3'-kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85-kDa regulatory subunit

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A novel function for the second C2 domain of synaptotagmin. Ca2+-triggered dimerization.

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Synaptotagmin I is a high affinity receptor for clathrin AP-2: implications for membrane recycling

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Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain

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Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain

21 January 2018

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21 January 2018

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Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complex

21 January 2018

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HEAT repeats in the Huntington's disease protein

21 January 2018

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The ancient regulatory-protein family of WD-repeat proteins

21 January 2018

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Phosphatidylinositol 3,5-bisphosphate defines a novel PI 3-kinase pathway in resting mouse fibroblasts

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

21 January 2018

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PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface

21 January 2018

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When is a lipid kinase not a lipid kinase? When it is a protein kinase

21 January 2018

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Activation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifs

21 January 2018

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PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

21 January 2018

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Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation

21 January 2018

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Specific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways

21 January 2018

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Structural and functional analysis of pp70S6k

21 January 2018

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Multiple independent inputs are required for activation of the p70 S6 kinase

21 January 2018

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

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A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

21 January 2018

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

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PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900617-0

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900617-0

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900617-0

Activation of PRK1 by phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. A comparison with protein kinase C isotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900617-0

The GTPase dynamin binds to and is activated by a subset of SH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900617-0

p70s6k function is essential for G1 progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900617-0

An 81 kd protein complexed with middle T antigen and pp60c-src: a possible phosphatidylinositol kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900617-0

PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900617-0

Receptor stimulated accumulation of phosphatidylinositol (3,4,5)-trisphosphate by G-protein mediated pathways in human myeloid derived cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900617-0

Real-time assay of the interaction of a GST fusion protein with a protein ligate using resonant mirror technique.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900617-0

GSK3: a SHAGGY frog story

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900617-0

Phosphatidylinositol (3,4,5)-trisphosphate stimulates phosphorylation of pleckstrin in human platelets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900617-0

10.1016/S0014-5793(97)00617-0

7 January 2021

Identifiers

DOI

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3 October 2017

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