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Jaks, STATs, cytokine signal transduction, and immunoregulation: are we there yet?
scientific article published on July 1997
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
9252115
retrieved
3 October 2017
review article
1 reference
stated in
Europe PubMed Central
title
Jaks, STATs, cytokine signal transduction, and immunoregulation: are we there yet?
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
9252115
retrieved
3 October 2017
author name string
O'Shea JJ
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9252115
retrieved
3 October 2017
language of work or name
English
0 references
publication date
1 July 1997
1 reference
stated in
Europe PubMed Central
PubMed ID
9252115
retrieved
3 October 2017
published in
Immunity
1 reference
stated in
Europe PubMed Central
PubMed ID
9252115
retrieved
3 October 2017
volume
7
1 reference
stated in
Europe PubMed Central
PubMed ID
9252115
retrieved
3 October 2017
page(s)
1-11
1 reference
stated in
Europe PubMed Central
PubMed ID
9252115
retrieved
3 October 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9252115
retrieved
3 October 2017
cites work
Functional diversity of helper T lymphocytes
1 reference
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Crossref
reference URL
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7 January 2021
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Interleukin-2 induces tyrosine phosphorylation of SHP-2 through IL-2 receptor beta chain
1 reference
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7 January 2021
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Classification of tyrosine kinases from Dictyostelium discoideum with two distinct, complete or incomplete catalytic domains
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7 January 2021
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PTP1D is a positive regulator of the prolactin signal leading to beta-casein promoter activation.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Haemopoietic receptors and helical cytokines
1 reference
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7 January 2021
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Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation and association of Stat3 with Src in v-Src-transformed cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Jak1 kinase is required for cell migrations and anterior specification in zebrafish embryos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Jak-STAT signaling induced by the v-abl oncogene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of inflammation, cytokine expression, and germinal center formation by BCL-6
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A transcription factor with SH2 and SH3 domains is directly activated by an interferon alpha-induced cytoplasmic protein tyrosine kinase(s)
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
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inferred from DOI database lookup
An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective STAT signaling by the leptin receptor in diabetic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Drosophila Tumorous-lethal hematopoietic oncogene is a dominant mutation in the hopscotch locus.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Contribution of STAT SH2 groups to specific interferon signaling by the Jak-STAT pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An interleukin-4-induced transcription factor: IL-4 Stat
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The JAK-STAT pathway in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokine receptor signalling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling through the hematopoietic cytokine receptors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STATs: signal transducers and activators of transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling by IL-2 and related cytokines: JAKs, STATs, and relationship to immunodeficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of constitutive activation of Janus kinases and signal transduction and activation of transcription factors in Philadelphia chromosome-positive acute lymphoblastic leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SH2 signaling in a lower eukaryote: a STAT protein that regulates stalk cell differentiation in dictyostelium.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of the murine IL-4 gene blocks Th2 cytokine responses.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generation and analysis of interleukin-4 deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-10-deficient mice develop chronic enterocolitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immune responses in interleukin-2-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A kinase-deficient splice variant of the human JAK3 is expressed in hematopoietic and epithelial cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The molecular basis of X-linked severe combined immunodeficiency: defective cytokine receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of STAT2 in the alpha interferon signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stat5a is mandatory for adult mammary gland development and lactogenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: A cytokine receptor superfamily oncogene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An amino acid substitution in the Drosophila hopTum-l Jak kinase causes leukemia-like hematopoietic defects.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of different Stat5 isoforms contributes to cell-type-restricted signaling in response to interferons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The common cytokine receptor gamma chain plays an essential role in regulating lymphoid homeostasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective lymphoid development in mice lacking Jak3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphocyte responses and cytokines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFNAR1 chain of the type I interferon receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective expression of an interleukin-12 receptor component by human T helper 1 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A common nuclear signal transduction pathway activated by growth factor and cytokine receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crucial role of Jak3 in negative selection of self-reactive T cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional responses to polypeptide ligands: the JAK-STAT pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Components of a Stat recognition code: evidence for two layers of molecular selectivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon-induced nuclear signalling by Jak protein tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional interactions between Stat5 and the glucocorticoid receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling mechanisms through cytokine receptors that share signal transducing receptor components
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role of Stat6 in IL-4 signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peripheral expression of Jak3 is required to maintain T lymphocyte function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A protein tyrosine kinase in the interferon alpha/beta signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Naturally occurring dominant negative variants of Stat5.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A JAK-STAT pathway regulates wing vein formation in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a Stat gene that functions in Drosophila development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular characterization of specific interactions between SHP-2 phosphatase and JAK tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of serine phosphorylation for formation of STAT-promoter complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980505-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1074-7613(00)80505-1
1 reference
stated in
Europe PubMed Central
PubMed ID
9252115
retrieved
3 October 2017
PubMed ID
9252115
1 reference
stated in
Europe PubMed Central
PubMed ID
9252115
retrieved
3 October 2017
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