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English
Ire1 has distinct catalytic mechanisms for XBP1/HAC1 splicing and RIDD.
scientific article published on 30 October 2014
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4486022
retrieved
4 October 2017
title
Ire1 has distinct catalytic mechanisms for XBP1/HAC1 splicing and RIDD.
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4486022
retrieved
4 October 2017
main subject
Ire1 complex
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1990332
author
Albert C. Koong
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4486022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25437541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
author name string
Arvin B Tam
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4486022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25437541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
Maho Niwa
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4486022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25437541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
publication date
30 October 2014
1 reference
stated in
Europe PubMed Central
PMC publication ID
4486022
retrieved
4 October 2017
published in
Cell Reports
1 reference
stated in
Europe PubMed Central
PMC publication ID
4486022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25437541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
volume
9
1 reference
stated in
Europe PubMed Central
PMC publication ID
4486022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25437541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
issue
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4486022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25437541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
page(s)
850-858
1 reference
stated in
Europe PubMed Central
PMC publication ID
4486022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25437541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
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Defects in IRE1 enhance cell death and fail to degrade mRNAs encoding secretory pathway proteins in the Arabidopsis unfolded protein response.
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IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.
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IRE1α activation protects mice against acetaminophen-induced hepatotoxicity
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Attenuation of yeast UPR is essential for survival and is mediated by IRE1 kinase
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Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response
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Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma
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Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering
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Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1
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IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates.
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Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
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Messenger RNA targeting to endoplasmic reticulum stress signalling sites.
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6 June 2018
The unfolded protein response signals through high-order assembly of Ire1
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Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing
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6 June 2018
IRE1 signaling affects cell fate during the unfolded protein response
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6 June 2018
The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response
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6 June 2018
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.
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6 June 2018
On the mechanism of sensing unfolded protein in the endoplasmic reticulum
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6 June 2018
Genome-scale approaches for discovering novel nonconventional splicing substrates of the Ire1 nuclease
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6 June 2018
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
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reference URL
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6 June 2018
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6 June 2018
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
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6 June 2018
Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway
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PubMed Central
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6 June 2018
Endoplasmic reticulum stress-induced mRNA splicing permits synthesis of transcription factor Hac1p/Ern4p that activates the unfolded protein response
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PubMed Central
reference URL
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6 June 2018
The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response
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PubMed Central
reference URL
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6 June 2018
tRNA ligase is required for regulated mRNA splicing in the unfolded protein response
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486022
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6 June 2018
BiP-bound and nonclustered mode of Ire1 evokes a weak but sustained unfolded protein response
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486022
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19 August 2018
Bypassing a Kinase Activity with an ATP-Competitive Drug
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486022
retrieved
19 August 2018
Identifiers
DOI
10.1016/J.CELREP.2014.09.016
1 reference
stated in
Europe PubMed Central
PMC publication ID
4486022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25437541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
PMC publication ID
4486022
1 reference
stated in
Europe PubMed Central
PMC publication ID
4486022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25437541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
PubMed publication ID
25437541
1 reference
stated in
Europe PubMed Central
PMC publication ID
4486022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25437541%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 June 2020
ResearchGate publication ID
269115240
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