(Q41587141)

4 October 2017

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title

The role of Jak3 in lymphoid development, activation, and signaling (English)

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4 October 2017

Thomis DC

1

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4 October 2017

Berg LJ

series ordinal

2

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4 October 2017

publication date

1 August 1997

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Current Opinion in Immunology

4 October 2017

published in

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4 October 2017

volume

9

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4 October 2017

issue

4

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4 October 2017

page(s)

541-547

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Cytokine receptor signalling

4 October 2017

cites work

1 reference

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7 January 2021

The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID

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7 January 2021

The molecular basis of X-linked severe combined immunodeficiency: the role of the interleukin-2 receptor gamma chain as a common gamma chain, gamma c.

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7 January 2021

Disruption of cytokine signaling in lymphoid development: unique contributions of the common cytokine gamma chain and the Jak3 kinase

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7 January 2021

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

1 reference

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7 January 2021

Defective lymphoid development in mice lacking Jak3

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7 January 2021

Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3

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7 January 2021

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

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7 January 2021

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

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7 January 2021

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

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7 January 2021

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

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7 January 2021

Immunodeficiencies caused by genetic defects in protein kinases

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7 January 2021

A novel X-linked combined immunodeficiency disease

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7 January 2021

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

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7 January 2021

In vitro correction of JAK3-deficient severe combined immunodeficiency by retroviral-mediated gene transduction

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7 January 2021

Genomic structure and promoter region of the murine Janus-family tyrosine kinase, Jak3

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7 January 2021

Jak3 maps to chromosome 8.

1 reference

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7 January 2021

Genomic sequence, organization, and chromosomal localization of human JAK3.

1 reference

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7 January 2021

A kinase-deficient splice variant of the human JAK3 is expressed in hematopoietic and epithelial cancer cells

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7 January 2021

Expression of Janus kinase 3 in human endothelial and other non-lymphoid and non-myeloid cells

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7 January 2021

Protein kinases in human breast cancer

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7 January 2021

Constitutive activation of different Jak tyrosine kinases in human T cell leukemia virus type 1 (HTLV-1) tax protein or virus-transformed cells

1 reference

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7 January 2021

Constitutively Activated Jak-STAT Pathway in T Cells Transformed with HTLV-I

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7 January 2021

Jak-STAT signaling induced by the v-abl oncogene

1 reference

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7 January 2021

The V-J recombination of T cell receptor-gamma genes is blocked in interleukin-7 receptor-deficient mice

1 reference

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7 January 2021

Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene

1 reference

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7 January 2021

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

1 reference

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7 January 2021

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

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7 January 2021

Interleukin 7 receptor-deficient mice lack gammadelta T cells

1 reference

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7 January 2021

Interleukin-7 receptor alpha is essential for the development of gamma delta + T cells, but not natural killer cells

1 reference

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7 January 2021

Characterization of thymic stromal-derived lymphopoietin (TSLP) in murine B cell development in vitro

1 reference

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7 January 2021

Differential effects of interleukin-15 and interleukin-2 on differentiation of bipotential T/natural killer progenitor cells

1 reference

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7 January 2021

Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor beta chain

1 reference

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7 January 2021

Critical role for the common cytokine receptor gamma chain in intrathymic and peripheral T cell selection

1 reference

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7 January 2021

A transgenic T cell receptor restores thymocyte differentiation in interleukin-7 receptor alpha chain-deficient mice

1 reference

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7 January 2021

Crucial role of Jak3 in negative selection of self-reactive T cells.

1 reference

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7 January 2021

The common cytokine receptor gamma chain plays an essential role in regulating lymphoid homeostasis

1 reference

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7 January 2021

Peripheral expression of Jak3 is required to maintain T lymphocyte function

1 reference

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7 January 2021

Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor

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7 January 2021

Interleukin-2 receptor common gamma-chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: selective induction of anti-apoptotic (bcl-2, bcl-xL) but not pro-apoptotic (bax, bcl-xS) gene expression

1 reference

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7 January 2021

Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells

1 reference

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7 January 2021

Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice.

1 reference

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7 January 2021

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

1 reference

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7 January 2021

Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta

1 reference

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7 January 2021

Signaling by IL-2 and related cytokines: JAKs, STATs, and relationship to immunodeficiency

1 reference

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7 January 2021

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

1 reference

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7 January 2021

The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes

1 reference

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7 January 2021

Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980108-2

7 January 2021

Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor gamma(c) chain for Janus kinase activation leading to T cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980108-2

7 January 2021

IL-2 signaling involves recruitment and activation of multiple protein tyrosine kinases by the IL-2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980108-2

7 January 2021

Interleukin‐7 activates p56lck and p59fyn, two tyrosine kinases associated with the p90 interleukin‐7 receptor in primary human T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980108-2

7 January 2021

Evidence for a role of phosphatidylinositol 3-kinase in IL-4-induced germline C epsilon transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980108-2

7 January 2021

Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980108-2

7 January 2021

Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980108-2

7 January 2021

Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980108-2

7 January 2021

Molecular characterization of specific interactions between SHP-2 phosphatase and JAK tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980108-2

7 January 2021

Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980108-2

7 January 2021

Protein tyrosine phosphatases in signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980108-2

7 January 2021

10.1016/S0952-7915(97)80108-2

Identifiers

DOI

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4 October 2017

1 reference