(Q41588728)

4 October 2017

title

Isolation and characterization of a mitomycin C-resistant variant of human colon carcinoma HT-29 cells (English)

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4 October 2017

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J H Lee

1

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4 October 2017

M Naito

series ordinal

2

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4 October 2017

M Nakajima

series ordinal

3

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4 October 2017

T Tsuruo

series ordinal

4

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4 October 2017

publication date

1 January 1993

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Cancer Chemotherapy and Pharmacology

4 October 2017

published in

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4 October 2017

volume

33

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4 October 2017

issue

3

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4 October 2017

page(s)

215-220

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Mitomycin C is not metabolized by but is an inhibitor of human kidney NAD(P)H: (quinone-acceptor)oxidoreductase

4 October 2017

cites work

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12 December 2020

DNA alkylation by enzyme-activated mitomycin C

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12 December 2020

NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity

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12 December 2020

NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals

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12 December 2020

Modification of the metabolism and cytotoxicity of bioreductive alkylating agents by dicoumarol in aerobic and hypoxic murine tumor cells

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12 December 2020

Cellular pharmacology of MX2, a new morpholino anthracycline, in human pleiotropic drug-resistant cells.

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12 December 2020

Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies

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12 December 2020

Enhancement of mitomycin C cytotoxicity to hypoxic tumor cells by dicoumarol in vivo and in vitro

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12 December 2020

Metabolism of diaziquone by NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells

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12 December 2020

Bioreductive activation of mitomycin C by DT-diaphorase

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12 December 2020

Anthracycline antibiotic-stimulated superoxide, hydrogen peroxide, and hydroxyl radical production by NADH dehydrogenase

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12 December 2020

Elevated DT-diaphorase activity and messenger RNA content in human non-small cell lung carcinoma: relationship to the response of lung tumor xenografts to mitomycin Cł

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12 December 2020

Occurrence of cytosolic protein and phosphoprotein changes in human colon tumor cells with the development of resistance to mitomycin C

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12 December 2020

Randomized clinical trial of mitomycin C as an adjunct to radiotherapy in head and neck cancer

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12 December 2020

Purification by cibacron blue F3GA dye affinity chromatography and comparison of NAD(P)H:quinone reductase (E.C.1.6.99.2) from rat liver cytosol and microsomes

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12 December 2020

Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1.

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12 December 2020

Mutagenicity of quinones: pathways of metabolic activation and detoxification

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12 December 2020

Purification and characterization of three forms of glutathione S-transferase A. A comparative study of the major YaYa-, YbYb- and YcYc-containing glutathione S-transferases

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12 December 2020

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil

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12 December 2020

Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity

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12 December 2020

Purified liver microsomal NADPH-cytochrome P-450 reductase. Spectral characterization of oxidation-reduction states

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12 December 2020

Increased sensitivity of quinone resistant cells to mitomycin C.

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12 December 2020

Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells

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12 December 2020

DT-diaphorase activity and mitomycin C sensitivity in non-transformed cell strains derived from members of a cancer-prone family.

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12 December 2020

Chinese hamster ovary cell lines resistant to mitomycin C under aerobic but not hypoxic conditions are deficient in DT-diaphorase

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12 December 2020

Activation of mitomycin C by NADPH:cytochrome P-450 reductase

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12 December 2020

Mechanisms of hypoxic and aerobic cytotoxicity of mitomycin C in Chinese hamster V79 cells.

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12 December 2020

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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12 December 2020

Bioactivation as a model for drug design bioreductive alkylation

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12 December 2020

Nitroxides block DNA scission and protect cells from oxidative damage

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12 December 2020

Drug-resistant mutants: selection and dominance analysis.

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12 December 2020

Identifiers

DOI

10.1007/BF00686219

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Dimensions Publication ID

4 October 2017

1044311048

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