(Q41596904)

4 October 2017

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title

The Li-Fraumeni syndrome: an inherited susceptibility to cancer (English)

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4 October 2017

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Evans SC

1

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4 October 2017

Lozano G

series ordinal

2

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4 October 2017

publication date

1 September 1997

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Trends in Molecular Medicine

4 October 2017

published in

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4 October 2017

volume

3

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4 October 2017

issue

9

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4 October 2017

page(s)

390-395

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Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?

4 October 2017

cites work

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Recommendations on predictive testing for germ line p53 mutations among cancer-prone individuals

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Different tumor-derived p53 mutants exhibit distinct biological activities

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Cancer. p53, guardian of the genome

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

p53: puzzle and paradigm

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

The p53-mdm-2 autoregulatory feedback loop

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

mdm2 expression is induced by wild type p53 activity

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Presence of a potent transcription activating sequence in the p53 protein

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

p53 domains: identification and characterization of two autonomous DNA-binding regions.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Definition of a consensus binding site for p53

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

A transcriptionally active DNA-binding site for human p53 protein complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901105-2

7 January 2021

10.1016/S1357-4310(97)01105-2

Identifiers

DOI

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4 October 2017

1 reference