(Q41625472)

English

Transition metal-mediated liposomal encapsulation of irinotecan (CPT-11) stabilizes the drug in the therapeutically active lactone conformation.

scientific article published on 25 October 2006

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Transition metal-mediated liposomal encapsulation of irinotecan (CPT-11) stabilizes the drug in the therapeutically active lactone conformation (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

transition metal

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Katarina Edwards

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

author name string

Euan Ramsay

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Jehan Alnajim

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Malathi Anantha

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Anitha Thomas

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Göran Karlsson

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Murray Webb

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Marcel Bally

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

publication date

25 October 2006

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Europe PubMed Central

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21 December 2019

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

23

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

12

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

2799-2808

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

pH-dependent association of SN-38 with lipid bilayers of a novel liposomal formulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

9-Nitrocamptothecin liposome aerosol treatment of human cancer subcutaneous xenografts and pulmonary cancer metastases in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topoisomerases: novel therapeutic targets in cancer chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metal complexes for therapy and diagnosis of drug resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous determination of the lactone and carboxylate forms of the camptothecin derivative CPT-11 and its metabolite SN-38 in plasma by high-performance liquid chromatography.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of doxorubicin and other lipophilic amines into large unilamellar vesicles in response to transmembrane pH gradients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Camptothecin design and delivery approaches for elevating anti-topoisomerase I activities in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photosensitive DNA cleavage and phage inactivation by copper(II)-camptothecin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liposomal encapsulation of topotecan enhances anticancer efficacy in murine and human xenograft models

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular, pharmacokinetic, and pharmacodynamic aspects of response to camptothecins: can we improve it?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The response of fluorescent amines to pH gradients across liposome membranes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of large unilamellar vesicles by a rapid extrusion procedure: characterization of size distribution, trapped volume and ability to maintain a membrane potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irinotecan-based combinations for the adjuvant treatment of stage III colon cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of transition metal-doxorubicin complexes inside liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structural basis of camptothecin interactions with human serum albumin: impact on drug stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical evaluation of CPT-11 and its active metabolite SN-38.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

pH gradient loading of anthracyclines into cholesterol-free liposomes: enhancing drug loading rates through use of ethanol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionophore-mediated uptake of ciprofloxacin and vincristine into large unilamellar vesicles exhibiting transmembrane ion gradients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An analytical method for irinotecan (CPT-11) and its metabolites using a high-performance liquid chromatography: parallel detection with fluorescence and mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simple and efficient liposomal encapsulation of topotecan by ammonium sulfate gradient: stability, pharmacokinetic and therapeutic evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor effect of liposome-incorporated camptothecin in human malignant xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocytosis of liposomes by macrophages: binding, acidification and leakage of liposomes monitored by a new fluorescence assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An evaluation of transmembrane ion gradient-mediated encapsulation of topotecan within liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Copper-topotecan complexation mediates drug accumulation into liposomes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liposomal irinotecan: formulation development and therapeutic assessment in murine xenograft models of colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17063397

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-006-9111-5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063397%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

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