(Q41639912)

5 October 2017

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title

The molecular genetics of pancreatic cancer (English)

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5 October 2017

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1 reference

Howe JR

1

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5 October 2017

Conlon KC

series ordinal

2

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5 October 2017

publication date

1 January 1997

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5 October 2017

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5 October 2017

volume

6

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5 October 2017

issue

1

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5 October 2017

page(s)

1-18

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5 October 2017

cites work

Cancer statistics, 1996.

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7 January 2021

Long-term survival after curative resection for pancreatic ductal adenocarcinoma. Clinicopathologic analysis of 5-year survivors

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7 January 2021

Treatment and survival in 13560 patients with pancreatic cancer, and incidence of the disease, in the West Midlands: An epidemiological study

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https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Results of resection for cancer of the exocrine pancreas: a study from the French Association of Surgery

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https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Long-term survival after resection for ductal adenocarcinoma of the pancreas. Is it really improving?

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https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Genetics and pancreatic cancer

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https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Familial pancreatic adenocarcinoma in three generations. A case report and a review of the literature

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https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Hereditary pancreatitis. Description of a fifth kindred and summary of clinical features

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Hereditary pancreatitis. A kindred without gross aminoaciduria

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https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Familial multiple endocrine neoplasia type I: a new look at pathophysiology

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https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

The multiple endocrine neoplasia syndromes

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https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Gastrinomas in the duodenums of patients with multiple endocrine neoplasia type 1 and the Zollinger-Ellison syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

The Radiographic Manifestations of von Hippel-Lindau Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Pancreatic lesions in von Hippel-Lindau disease: prevalence, clinical significance, and CT findings

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https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Identification of the von Hippel-Lindau disease tumor suppressor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Systemic cancer and the FAMMM syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Pancreatic cancer and the familial atypical multiple mole melanoma (FAMMM) syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

The association between cholangiocarcinoma and hereditary nonpolyposis colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Gardner syndrome in a man with an interstitial deletion of 5q.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Nonrandom chromosomal rearrangements in pancreatic carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Karyotypic abnormalities in tumours of the pancreas

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Chromosome abnormalities in pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

The influence of tumour cell DNA content on survival in colorectal cancer: a detailed analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Ploidy as prognostic determinant in pancreatic cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Factors influencing survival after resection of pancreatic cancer. A DNA analysis and a histomorphologic study

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Pancreaticoduodenectomy for cancer of the head of the pancreas. 201 patients

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Prognostic significance of DNA ploidy in adenocarcinoma of the pancreas. A flow cytometric study of paraffin-embedded specimens.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Nuclear DNA distribution pattern of the parenchymal cells in adenocarcinomas of the pancreas and in chronic pancreatitis. A study of archival specimens using both image and flow cytometry

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Clinical significance of nuclear DNA content in pancreatic carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Prognostic markers of colorectal cancer: an evaluation of DNA content, epidermal growth factor receptor, and Ki-67

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Flow cytometric analysis of nuclear DNA content of duct cell carcinoma of the pancreas

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

DNA ploidy and cell-cycle analysis in pancreatic and ampullary carcinoma: flow cytometric study of formalin-fixed paraffin-embedded tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Evaluation of DNA Nuclear Pattern as a Prognostic Determinant in Resected Pancreatic Ductal Adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

A comparison of flow cytometric and absorption cytometric DNA values as prognostic indicators for pancreatic carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Heterogeneity in the nuclear DNA content of cells in carcinomas of the biliary tract and pancreas

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

K-ras gene mutation as a pathogenetic and diagnostic marker in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Genetic alterations during colorectal-tumor development

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Prevalence of ras gene mutations in human colorectal cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

1 reference

7 January 2021

Pancreatic ductal adenocarcinomas induced in Syrian hamsters by N-nitrosobis(2-oxopropyl)amine contain a c-Ki-ras oncogene with a point-mutated codon 12.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Detection of high incidence of K-ras oncogenes during human colon tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

K-ras-2 topographic genotyping of pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Analysis of ras gene mutations in biliary and pancreatic tumors by polymerase chain reaction and direct sequencing

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Pancreatic cancer in Europe: Ki-ras gene mutation pattern shows geographical differences

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

High frequency of Ki-ras codon 12 mutations in pancreatic adenocarcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Frequent glycine-to-aspartic acid mutations at codon 12 of c-Ki-ras gene in human pancreatic cancer in Japanese

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

ras mutations in endocrine tumors: mutation detection by polymerase chain reaction-single strand conformation polymorphism

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Distinguishing Pancreatic Carcinoma From Other Periampullary Carcinomas by Analysis of Mutations in the Kirsten-ras Oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

ras-family gene mutations in neoplasia of the ampulla of vater

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Exocrine pancreatic tumours and their histological classification. A study based on 167 autopsy and 97 surgical cases

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Acinar cell carcinoma of the pancreas. A clinicopathologic study of 28 cases

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Detection of c-Ki-ras mutation by PCR/RFLP analysis and diagnosis of pancreatic adenocarcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Detection of point mutations in the K-ras oncogene at codon 12 in pure pancreatic juice for diagnosis of pancreatic carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Diagnosis of pancreatic adenocarcinoma by polymerase chain reaction from pancreatic secretions

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Identification of K-ras oncogene mutations in the pure pancreatic juice of patients with ductal pancreatic cancers.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Localization of gene for human p53 tumour antigen to band 17p13.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Cancer. p53, guardian of the genome

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Suppression of human colorectal carcinoma cell growth by wild-type p53

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Different tumor-derived p53 mutants exhibit distinct biological activities

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

p53 mutations in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Association of p53 gene mutations with short survival in pancreatic adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

The gene for familial polyposis coli maps to the long arm of chromosome 5.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Localization of the gene for familial adenomatous polyposis on chromosome 5.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

A genetic model for colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Identification of FAP locus genes from chromosome 5q21

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Identification of deletion mutations and three new genes at the familial polyposis locus

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Identification and characterization of the familial adenomatous polyposis coli gene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Identification of a Gene Located at Chromosome 5q21 that Is Mutated in Colorectal Cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Abnormalities affecting the APC and MCC tumour suppressor gene loci on chromosome 5q occur frequently in gastric cancer but not in pancreatic cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Mutations of the adenomatous polyposis coli gene in the mutation cluster region: comparison of human pancreatic and colorectal cancers.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Identification of a chromosome 18q gene that is altered in colorectal cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Frequent alterations of the tumor suppressor genes p53 and DCC in human pancreatic carcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Abnormalities of the RB1 and DCC tumor suppressor genes: Uncommon in human pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Amplification of c-erbB-2 oncogene in human adenocarcinomas in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Different structural alterations upregulate in vitro tyrosine kinase activity and transforming potency of the erbB-2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Expression of c-erbB-2 in Human Pancreatic Adenocarcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

The c-erb B-2 proto-oncogene in human pancreatic cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

The erbB-3 gene in human pancreatic cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

A cell cycle regulator potentially involved in genesis of many tumor types

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Frequent mutations of CDKN2 in primary pancreatic adenocarcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Increased Risk of Pancreatic Cancer in Melanoma-Prone Kindreds withp16INK4Mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

A Familial Syndrome of Pancreatic Cancer and Melanoma with a Mutation in theCDKN2Tumor-Suppressor Gene

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Microsatellite instability in cancer of the proximal colon

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Clues to the pathogenesis of familial colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Mutation of a mutL homolog in hereditary colon cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Pancreatic carcinoma and hereditary nonpolyposis colorectal cancer: a family study

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Ki-ras oncogene activation in preinvasive pancreatic cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Detection of point mutations in the Kirsten-ras oncogene provides evidence for the multicentricity of pancreatic carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Frequent K-ras mutations and absence of p53 mutations in mucin-producing tumors of the pancreas

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0960-7404%2897%2900001-7

7 January 2021

10.1016/S0960-7404(97)00001-7

Identifiers

DOI

1 reference

5 October 2017

1 reference