(Q41641598)

English

Thalidomide and derivatives: immunological investigations of tumour necrosis factor-alpha (TNF-alpha) inhibition suggest drugs capable of selective gene regulation

scientific article published on November 1997

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scholarly article

1 reference

Europe PubMed Central

6 October 2017

1 reference

Europe PubMed Central

Thalidomide and derivatives: immunological investigations of tumour necrosis factor-alpha (TNF-alpha) inhibition suggest drugs capable of selective gene regulation (English)

1 reference

Europe PubMed Central

6 October 2017

0 references

0 references

author name string

S M McHugh

1

1 reference

Europe PubMed Central

6 October 2017

T L Rowland

2

1 reference

Europe PubMed Central

6 October 2017

publication date

1 November 1997

1 reference

Europe PubMed Central

6 October 2017

Clinical and Experimental Immunology

1 reference

Europe PubMed Central

6 October 2017

110

1 reference

Europe PubMed Central

6 October 2017

151-154

1 reference

Europe PubMed Central

6 October 2017

2

1 reference

Europe PubMed Central

6 October 2017

Thalidomide as an anti-TNF-alpha inhibitor: implications for clinical use.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Biological and biochemical inhibitors of the NF-kappa B/Rel proteins and cytokine synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Treatment of colitis in Behçet's disease with thalidomide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Benzylphthalimides and phenethylphthalimides with thalidomide-like activity on the production of tumor necrosis factor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Selection of novel analogs of thalidomide with enhanced tumor necrosis factor alpha inhibitory activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Cell type-/inducer-specific bidirectional regulation by thalidomide and phenylphthalimides of tumor necrosis factor-alpha production and its enantio-dependence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

A tumor necrosis factor (TNF) receptor fragment attenuates TNF-alpha- and muramyl dipeptide-induced sleep and fever in rabbits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Structural modifications of thalidomide produce analogs with enhanced tumor necrosis factor inhibitory activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

New roles for thalidomide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Binding of thalidomide to alpha1-acid glycoprotein may be involved in its inhibition of tumor necrosis factor alpha production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Inducer-specific bidirectional regulation by thalidomide and phenylphthalimides of tumor necrosis factor-alpha production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Thalidomide can be either agonistic or antagonistic to LPS evoked synthesis of TNF-alpha by mononuclear cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Tumor necrosis factor alpha gene regulation in activated T cells involves ATF-2/Jun and NFATp

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Mechanisms of tumor necrosis factor-alpha (TNF-alpha) hyperalgesia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Angiogenesis: mechanistic insights, neovascular diseases, and therapeutic prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Thalidomide derivatives and the immune system. I. Changes in the pattern of integrin receptors and other surface markers on T lymphocyte subpopulations of marmoset blood.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

(S)-form of alpha-methyl-N(alpha)-phthalimidoglutarimide, but not its (R)-form, enhanced phorbol ester-induced tumor necrosis factor-alpha production by human leukemia cell HL-60: implication of optical resolution of thalidomidal effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Thalidomide does not perturb CD2, CD4, CD5, CD8, HLA-DR, or HLA-A, B, C molecules in vitro on the membranes of cells with immune potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Clinical experience with thalidomide in the management of severe oral and genital ulceration in conditions such as Behçet's disease: use of neurophysiological studies to detect thalidomide neuropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

NF-kappa B and rel proteins in innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Treatment of cutaneous and pulmonary sarcoidosis with thalidomide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Does thalidomide affect IL-2 response and production?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Influence of supidimide on brain neurotransmitter systems of rats and mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

The metabolism of thalidomide: the spontaneous hydrolysis of thalidomide in solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Treatment of refractory rheumatoid arthritis--the thalidomide experience

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

Homeobox genes in normal hematopoiesis and leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265499

29 August 2018

The effect of thalidomide on BCG-induced granulomas in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thalidomide increases the synthesis of IL-2 in cultures of human mononuclear cells stimulated with Concanavalin-A, Staphylococcal enterotoxin A, and purified protein derivative

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent inhibition of tumor necrosis factor-alpha production by tetrafluorothalidomide and tetrafluorophthalimides

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmentation by phthalimides of phorbol ester-induced expression of tumor necrosis factor alpha message

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enantioselective inhibition of TNF-alpha release by thalidomide and thalidomide-analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thalidomide therapy of established collagen-induced arthritis (CIA) not accompanied by an evident Th2 shift

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation by thalidomide and dexamethasone of cytokine expression in human peripheral blood mononuclear cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

THALIDOMIDE IN THE TREATMENT OF LEPRA REACTIONS

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolic fate of supidimide in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thalidomide induction of bone marrow transplantation tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of severe colitis in Behçet's syndrome with thalidomide (CG-217)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thalidomide for the treatment of chronic graft-versus-host disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Influence of Thalidomide on the Clinical and Immunologic Manifestation of Erythema Nodosum Leprosum

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacologic inhibitors of tumor necrosis factor production exert differential effects in lethal endotoxemia and in infection with live microorganisms in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunosuppressive drug thalidomide induces T helper cell type 2 (Th2) and concomitantly inhibits Th1 cytokine production in mitogen- and antigen-stimulated human peripheral blood mononuclear cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine regulation of disease progression in leprosy and tuberculosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thalidomide inhibits tumor necrosis factor-alpha production by lipopolysaccharide- and lipoarabinomannan-stimulated human microglial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367395

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2249.1997.TB08310.X

1 reference

Europe PubMed Central

6 October 2017

0 references

1 reference

Europe PubMed Central

6 October 2017

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0 references

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