(Q41657181)

English

Distinct splicing signatures affect converged pathways in myelodysplastic syndrome patients carrying mutations in different splicing regulators

scientific article published on 4 August 2016

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scholarly article

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Europe PubMed Central

6 October 2017

Distinct splicing signatures affect converged pathways in myelodysplastic syndrome patients carrying mutations in different splicing regulators (English)

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6 October 2017

myelodysplastic syndrome

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Christopher DeBoever

7

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11 June 2020

Anuhar Chaturvedi

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11 June 2020

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11 June 2020

author name string

Jinsong Qiu

1

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11 June 2020

Bing Zhou

2

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11 June 2020

Felicitas Thol

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11 June 2020

Yu Zhou

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11 June 2020

Liang Chen

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11 June 2020

Jiayi Hou

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11 June 2020

Hairi Li

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11 June 2020

Arnold Ganser

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Rafael Bejar

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11 June 2020

Dong-Er Zhang

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11 June 2020

Xiang-Dong Fu

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11 June 2020

Michael Heuser

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11 June 2020

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4 August 2016

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6 October 2017

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11 June 2020

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11 June 2020

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11 June 2020

1535-1549

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11 June 2020

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Disease-associated mutation in SRSF2 misregulates splicing by altering RNA-binding affinities

1 reference

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6 June 2018

SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029452

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The genetics of splicing in neuroblastoma

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ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP.

1 reference

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6 June 2018

Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome

1 reference

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6 June 2018

Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

1 reference

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6 June 2018

U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029452

6 June 2018

U2AF1 mutations alter splice site recognition in hematological malignancies

1 reference

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6 June 2018

Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS.

1 reference

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6 June 2018

Next-generation sequencing of translocation renal cell carcinoma reveals novel RNA splicing partners and frequent mutations of chromatin-remodeling genes

1 reference

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Identification of a BRCA1-mRNA splicing complex required for efficient DNA repair and maintenance of genomic stability

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Expression microarray analysis reveals alternative splicing of LAMA3 and DST genes in head and neck squamous cell carcinoma

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NOTCH2 and FLT3 gene mis-splicings are common events in patients with acute myeloid leukemia (AML): new potential targets in AML

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Unique role of SRSF2 in transcription activation and diverse functions of the SR and hnRNP proteins in gene expression regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029452

6 June 2018

Landscape of genetic lesions in 944 patients with myelodysplastic syndromes

1 reference

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6 June 2018

Clinical and biological implications of driver mutations in myelodysplastic syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029452

6 June 2018

Patterns of missplicing due to somatic U2AF1 mutations in myeloid neoplasms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029452

6 June 2018

RNA sequencing of cancer reveals novel splicing alterations

1 reference

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6 June 2018

Isoform level expression profiles provide better cancer signatures than gene level expression profiles

1 reference

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6 June 2018

Genome-wide analysis reveals SR protein cooperation and competition in regulated splicing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029452

6 June 2018

MBTD1 is associated with Pr-Set7 to stabilize H4K20me1 in mouse oocyte meiotic maturation

1 reference

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6 June 2018

Revised international prognostic scoring system for myelodysplastic syndromes

1 reference

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6 June 2018

The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus

1 reference

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6 June 2018

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6 June 2018

RASL-seq for massively parallel and quantitative analysis of gene expression

1 reference

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6 June 2018

Clonal architecture of secondary acute myeloid leukemia

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6 June 2018

Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5029452

6 June 2018

Normal hematopoietic stem cell function in mice with enforced expression of the Hippo signaling effector YAP1

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6 June 2018

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1 reference

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6 June 2018

Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes

1 reference

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6 June 2018

Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts

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Clinical effect of point mutations in myelodysplastic syndromes

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Cancer-associated regulation of alternative splicing

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6 June 2018

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

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Alternative isoform regulation in human tissue transcriptomes

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Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis

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The implications of alternative splicing in the ENCODE protein complement

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Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay

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Identification and analysis of alternative splicing events conserved in human and mouse

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6 June 2018

Transcriptome and genome conservation of alternative splicing events in humans and mice.

1 reference

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6 June 2018

Gene expression profiling predicts clinical outcome of breast cancer

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6 June 2018

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6 June 2018

Frequency and prognostic impact of casein kinase 1A1 mutations in MDS patients with deletion of chromosome 5q.

1 reference

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Inter-observer variance with the diagnosis of myelodysplastic syndromes (MDS) following the 2008 WHO classification.

1 reference

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18 August 2018

A prognostic score for patients with lower risk myelodysplastic syndrome

1 reference

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18 August 2018

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time-dependent prognostic scoring system for predicting survival and leukemic evolution in myelodysplastic syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/27492256

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of Gene Expression–Based Prognostic Markers in the Hematopoietic Stem Cells of Patients With Myelodysplastic Syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/27492256

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1261/RNA.056101.116

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Europe PubMed Central

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11 June 2020

1 reference

Europe PubMed Central

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11 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27492256%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

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