(Q41678499)

7 October 2017

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title

Roles of ubiquitin-mediated proteolysis in cell cycle control (English)

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7 October 2017

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A Hershko

1

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7 October 2017

1 December 1997

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Current Opinion in Cell Biology

7 October 2017

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7 October 2017

9

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7 October 2017

788-799

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7 October 2017

6

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Lessons from the discovery of the ubiquitin system

7 October 2017

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

The ubiquitin system for protein degradation

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Ubiquitin-dependent protein degradation

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

How proteolysis drives the cell cycle

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

At the heart of the budding yeast cell cycle

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Phosphorylation and proteolysis: partners in the regulation of cell division in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

p34Cdc28-mediated control of Cln3 cyclin degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Rapid degradation of the G1 cyclin Cln2 induced by CDK-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Linkage of replication to start by the Cdk inhibitor Sic1.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

The cyclin-dependent kinase inhibitor p40SIC1 imposes the requirement for Cln G1 cyclin function at Start

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

SIC1 is ubiquitinated in vitro by a pathway that requires CDC4, CDC34, and cyclin/CDK activities

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Cell cycle control of DNA replication.

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Translational control of p27Kip1 accumulation during the cell cycle

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Cyclin E-CDK2 is a regulator of p27Kip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Cyclin is degraded by the ubiquitin pathway

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

E2-C, a cyclin-selective ubiquitin carrier protein required for the destruction of mitotic cyclins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

A ubiquitin-conjugating enzyme in fission yeast that is essential for the onset of anaphase in mitosis

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

RanBP2 associates with Ubc9p and a modified form of RanGAP1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

The TPR snap helix: a novel protein repeat motif from mitosis to transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Cdc16p, Cdc23p and Cdc27p form a complex essential for mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Identification of BIME as a subunit of the anaphase-promoting complex

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Cell cycle: reaching for a role for the Cks proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Xe-p9, a Xenopus Suc1/Cks homolog, has multiple essential roles in cell cycle control.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Binding of activated cyclosome to p13(suc1). Use for affinity purification.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Requirement for PP1 phosphatase and 20S cyclosome/APC for the onset of anaphase is lessened by the dosage increase of a novel gene sds23+.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

The requirements for protein synthesis and degradation, and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Regulation of B-type cyclin proteolysis by Cdc28-associated kinases in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Cut2 proteolysis required for sister-chromatid seperation in fission yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Fission yeast Cut2 required for anaphase has two destruction boxes.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Separation of sister chromatids in mitosis requires the Drosophila pimples product, a protein degraded after the metaphase/anaphase transition.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Cyclin-like accumulation and loss of the putative kinetochore motor CENP-E results from coupling continuous synthesis with specific degradation at the end of mitosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

The yeast CDC16 and CDC27 genes restrict DNA replication to once per cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

A developmental timer regulates degradation of cyclin E1 at the midblastula transition during Xenopus embryogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

Distinct molecular mechanism regulate cell cycle timing at successive stages of Drosophila embryogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

The spindle assembly checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2897%2980079-8

7 January 2021

10.1016/S0955-0674(97)80079-8

Identifiers

DOI

1 reference

7 October 2017

1 reference

PubMed ID

9425343