(Q41681702)

7 October 2017

title

Multidrug resistance modulators and doxorubicin synergize to elevate ceramide levels and elicit apoptosis in drug-resistant cancer cells (English)

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7 October 2017

main subject

multiple drug resistance

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A Lucci

1

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7 October 2017

T Y Han

2

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7 October 2017

Y Y Liu

3

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7 October 2017

A E Giuliano

4

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7 October 2017

M C Cabot

5

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7 October 2017

language of work or name

English

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publication date

1 July 1999

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7 October 2017

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7 October 2017

volume

86

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7 October 2017

issue

2

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7 October 2017

page(s)

300-311

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Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes

7 October 2017

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Biochemistry of multidrug resistance mediated by the multidrug transporter

21 January 2018

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P-glycoprotein, multidrug resistance and tumor progression

21 January 2018

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Expression of resistance factors (P-glycoprotein, glutathione S-transferase-pi, and topoisomerase II) and their interrelationship to proto-oncogene products in renal cell carcinomas.

21 January 2018

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Interaction of tamoxifen with the multidrug resistance P-glycoprotein.

21 January 2018

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Comparative study on reversal efficacy of SDZ PSC 833, cyclosporin A and verapamil on multidrug resistance in vitro and in vivo.

21 January 2018

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Accumulation of glucosylceramides in multidrug-resistant cancer cells

21 January 2018

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Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells

21 January 2018

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Glucosylceramides stimulate murine epidermal hyperproliferation.

21 January 2018

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Cell cycle arrest induced by an inhibitor of glucosylceramide synthase. Correlation with cyclin-dependent kinases

21 January 2018

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Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells

21 January 2018

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

21 January 2018

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Ceramide: an intracellular signal for apoptosis

21 January 2018

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Anti-immunoglobulin-induced apoptosis in WEHI 231 cells involves the slow formation of ceramide from sphingomyelin and is blocked by bcl-XL.

21 January 2018

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Toremifene: pharmacologic and pharmacokinetic basis of reversing multidrug resistance.

21 January 2018

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Sufficient levels of quinine in the serum circumvent the multidrug resistance of the human leukemic cell line K562/ADM.

21 January 2018

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Cyclosporin A reverses vincristine and daunorubicin resistance in acute lymphatic leukemia in vitro

21 January 2018

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Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

21 January 2018

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Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis

21 January 2018

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Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.

21 January 2018

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Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway

21 January 2018

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MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine

21 January 2018

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The multidrug resistance modulator SDZ PSC 833 is a potent activator of cellular ceramide formation.

21 January 2018

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Resistance modification by PSC-833, a novel non-immunosuppressive cyclosporin A

21 January 2018

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Superiority of cyclosporin A over PSC-833 in enhancement of VP-16 efficacy in murine tumors in vivo

21 January 2018

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Clinical trials of agents that reverse multidrug resistance. A literature review

21 January 2018

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Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifen

21 January 2018

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Apoptosis and cancer chemotherapy

21 January 2018

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Tamoxifen retards glycosphingolipid metabolism in human cancer cells

21 January 2018

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Cellular and biochemical characterization of VX-710 as a chemosensitizer: reversal of P-glycoprotein-mediated multidrug resistance in vitro

21 January 2018

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10.1002/(SICI)1097-0142(19990715)86:2<300::AID-CNCR14>3.0.CO;2-H

21 January 2018

Identifiers

DOI

1 reference

7 October 2017

1 reference