(Q41682192)

7 October 2017

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title

A risk-benefit assessment of iron-chelation therapy (English)

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7 October 2017

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J B Porter

1

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7 October 2017

publication date

1 December 1997

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7 October 2017

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7 October 2017

volume

17

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7 October 2017

issue

6

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7 October 2017

page(s)

407-421

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Desferrioxamine-induced iron excretion in humans

7 October 2017

cites work

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12 December 2020

Ocular changes in patients undergoing long-term desferrioxamine treatment

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12 December 2020

Reassessment of the Use of Desferrioxamine B in Iron Overload

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12 December 2020

Kinetics of removal and reappearance of non-transferrin-bound plasma iron with deferoxamine therapy

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12 December 2020

The toxic effects of desferrioxamine

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12 December 2020

A unique rodent model for both the cardiotoxic and hepatotoxic effects of prolonged iron overload

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12 December 2020

Effective chelation of iron in beta thalassaemia with the oral chelator 1,2-dimethyl-3-hydroxypyrid-4-one.

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12 December 2020

The interaction of hydroxypyridinones with human serum transferrin and ovotransferrin

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12 December 2020

Pulmonary syndrome in patients with thalassemia major receiving intravenous deferoxamine infusions

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12 December 2020

Iron-chelation therapy with oral deferiprone in patients with thalassemia major

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12 December 2020

Urinary metabolic profiles in human and rat of 1,2-dimethyl- and 1,2-diethyl-substituted 3-hydroxypyridin-4-ones

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12 December 2020

Intravenous infusion pharmacokinetics of desferrioxamine in thalassaemic patients

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12 December 2020

Iron excretion in thalassaemia major after administration of chelating agents

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12 December 2020

High-dose desferrioxamine as a cause of growth failure in thalassemic patients

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12 December 2020

Autoantibodies in thalassaemia major: relationship with oral iron chelator L1

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12 December 2020

Non-ferritin, non-heme iron pools in rat tissues

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12 December 2020

Cerebral and ocular toxicity induced by desferrioxamine

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12 December 2020

Separation and identification of desferrioxamine and its iron chelating metabolites by high-performance liquid chromatography and fast atom bombardment mass spectrometry: choice of complexing agent and application to biological fluids

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12 December 2020

Results of long‐term deferiprone (L1) therapy: a report by the International Study Group on Oral Iron Chelators

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12 December 2020

Acute changes in renal function associated with deferoxamine therapy

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12 December 2020

Comparison of oral iron chelator L1 and desferrioxamine in iron-loaded patients

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12 December 2020

Pneumocystis carinii pneumonia as a complication of desferrioxamine therapy

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12 December 2020

Storage iron kinetics. 3. Study of desferrioxamine action by selective radioiron labels of RE and parenchymal cells

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12 December 2020

Thrombocytopenia associated with intravenous desferrioxamine

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12 December 2020

Long-term assessment of efficacy and safety of L1, an oral iron chelator, in transfusion dependent thalassaemia: Indian trial

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12 December 2020

Long-term desferrioxamine therapy in thalassemia

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12 December 2020

Comparison of the subacute toxicity and efficacy of 3-hydroxypyridin-4-one iron chelators in overloaded and nonoverloaded mice

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12 December 2020

Survival in medically treated patients with homozygous beta-thalassemia

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12 December 2020

Ferrioxamine excretion in iron-loaded man

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12 December 2020

The environment of the lipoxygenase iron binding site explored with novel hydroxypyridinone iron chelators

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12 December 2020

Evaluation of a new method of administration of the iron chelating agent deferoxamine

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12 December 2020

DESFERRIOXAMINE AND SYSTEMIC YERSINIOSIS

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12 December 2020

Interaction of transferrin with iron-loaded rat peritoneal macrophages

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12 December 2020

The effect of iron chelation on haemopoiesis in MDS patients with transfusional iron overload

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12 December 2020

Rapid removal of excessive iron with daily, high-dose intravenous chelation therapy

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12 December 2020

Design of orally active iron chelators

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12 December 2020

The development of iron chelating drugs

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12 December 2020

Mechanism of iron chelation in the hypertransfused rat: definition of two alternative pathways of iron mobilization

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12 December 2020

Fatal systemic lupus erythematosus in patient taking oral iron chelator L1

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12 December 2020

Cell cycle synchronization and growth inhibition by 3-hydroxypyridin-4-one iron chelators in leukemia cell lines

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12 December 2020

Iron toxicity and oxygen radicals

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12 December 2020

Intensive Iron-Chelation Therapy with Desferrioxamine in Iron-Loading Anaemias

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12 December 2020

Estimation of statistical moments for desferrioxamine and its iron and aluminum chelates: contribution to optimisation of therapy in uremic patients

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12 December 2020

Pulmonary toxic effects of continuous desferrioxamine administration in acute iron poisoning

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12 December 2020

Agranulocytosis and thrombocytopenia in patient with Blackfan-Diamond anaemia during oral chelator trial

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12 December 2020

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12 December 2020

Desferrioxamine to improve cardiac function in iron-overloaded patients with thalassemia major

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12 December 2020

Rapid desensitisation for desferrioxamine anaphylactic reaction

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12 December 2020

Toxicity of oral iron chelator L1

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12 December 2020

Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4(1H)-pyridinones: orally active iron chelators with clinical potential

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12 December 2020

Yersinia sepsis in patients with iron overload treated with deferoxamine

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12 December 2020

Long-term Chelation Therapy in Thalassaemia Major: Effect on Liver Iron Concentration, Liver Histology, and Clinical Progress

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12 December 2020

Development of iron-chelating agents for clinical use

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12 December 2020

Animal toxicology of iron chelator L1

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12 December 2020

Pharmacokinetics of the oral iron chelator deferiprone (L1) in patients with iron overload.

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12 December 2020

Low molecular weight intracellular iron transport compounds

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12 December 2020

The effects of subcutaneous deferoxamine administration on renal function in thalassemia major

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12 December 2020

Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major

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12 December 2020

Growth and development in thalassaemia major patients with severe bone lesions due to desferrioxamine.

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12 December 2020

Iron-chelating therapy and the treatment of thalassemia.

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12 December 2020

Iron-balance and dose-response studies of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in iron-loaded patients with sickle cell disease

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12 December 2020

Survival and desferrioxamine in thalassaemia major.

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12 December 2020

Advances in the use of iron-chelating agents for the treatment of iron overload

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12 December 2020

Acute aphasia and loss of vision with desferrioxamine overdose

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12 December 2020

Rapid desensitisation for desferrioxamine anaphylactoid reaction.

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12 December 2020

Mechanism of Desferrioxamine-Induced Iron Excretion in Thalassaemia

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12 December 2020

Survival and causes of death in thalassaemia major

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12 December 2020

Desferrioxamine ototoxicity in an adult transfusion-dependent population

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12 December 2020

Iron overload: causes and consequences

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12 December 2020

Pharmacokinetic studies in humans with the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one

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12 December 2020

Desferrioxamine ototoxicity: evaluation of risk factors in thalassaemic patients and guidelines for safe dosage

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12 December 2020

1,2-Dimethyl-3-hydroxypyrid-4-one, an orally active chelator for treatment of iron overload

1 reference

12 December 2020

A novel delivery system for continuous desferrioxamine infusion in transfusional iron overload

1 reference

12 December 2020

Efficacy and possible adverse effects of the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in thalassemia major

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12 December 2020

Iron state and hepatic disease in patients with thalassaemia major, treated with long term subcutaneous desferrioxamine

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12 December 2020

Non-specific serum iron in thalassaemia: an abnormal serum iron fraction of potential toxicity

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12 December 2020

Visual and auditory neurotoxicity in patients receiving subcutaneous deferoxamine infusions

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12 December 2020

Depletion of excessive liver iron stores with desferrioxamine

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12 December 2020

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12 December 2020

Sustained normalization of cardiac function by chelation therapy in thalassaemia major

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12 December 2020

Iron mobilization from ferritin by chelating agents

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12 December 2020

Mucormycosis infection in dialysis patients

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12 December 2020

Ocular toxicity of high-dose intravenous desferrioxamine

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12 December 2020

The relationship of intracellular iron chelation to the inhibition and regeneration of human ribonucleotide reductase

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12 December 2020

Results of long-term iron-chelating therapy

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12 December 2020

10.2165/00002018-199717060-00006

Identifiers

DOI

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Dimensions Publication ID

7 October 2017

1046760861

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Fatcat ID

release_dg4smyqlwvfujmcmoicwoc4q6q

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Fatcat

https://api.fatcat.wiki/v0/release/dg4smyqlwvfujmcmoicwoc4q6q

24 November 2022

mapped directly with Wikidata item

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