(Q41697730)

7 October 2017

A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes (English)

1 reference

7 October 2017

1

1 reference

7 October 2017

R Y Hampton

2

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PubMed ID

10531376

7 October 2017

language of work or name

English

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publication date

1 October 1999

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Journal of Biological Chemistry

7 October 2017

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7 October 2017

274

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7 October 2017

31671-31678

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7 October 2017

44

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Regulation of the mevalonate pathway

7 October 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Partial deletion of membrane-bound domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase eliminates sterol-enhanced degradation and prevents formation of crystalloid endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Sequence determinants for regulated degradation of yeast 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Expression of heterologous genes in Saccharomyces cerevisiae from vectors utilizing the glyceraldehyde-3-phosphate dehydrogenase gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Four major transcriptional responses in the methionine/threonine biosynthetic pathway of Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

A new efficient gene disruption cassette for repeated use in budding yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

In vivo examination of membrane protein localization and degradation with green fluorescent protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Molecular cloning and regulation of the expression of the MET2 gene of Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Measuring protein degradation with green fluorescent protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Isolation and primary structure of the ERG9 gene of Saccharomyces cerevisiae encoding squalene synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Molecular cloning and characterization of the yeast gene for squalene synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Isolation and properties of yeast mutants affected in farnesyl diphosphate synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

The mechanism of action of terbinafine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

The gene encoding squalene epoxidase from Saccharomyces cerevisiae: cloning and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Terbinafine: mode of action and properties of the squalene epoxidase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Molecular cloning and expression of rat squalene epoxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

The LPP1 and DPP1 gene products account for most of the isoprenoid phosphate phosphatase activities in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Ornithine decarboxylase antizyme: a novel type of regulatory protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

Degradation signal masking by heterodimerization of MATalpha2 and MATa1 blocks their mutual destruction by the ubiquitin-proteasome pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Inhibitors Unmask Cryptic Regulatory Mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.44.31671

21 January 2018

Identifiers

DOI

10.1074/JBC.274.44.31671

1 reference

7 October 2017

1 reference

PubMed ID

10531376