(Q41703793)

7 October 2017

title

Aryl ester prodrugs of cyclic HPMPC. I: Physicochemical characterization and in vitro biological stability (English)

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7 October 2017

R Oliyai

1

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7 October 2017

J P Shaw

2

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7 October 2017

C M Sueoka-Lennen

3

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7 October 2017

K C Cundy

4

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7 October 2017

M N Arimilli

5

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7 October 2017

R J Jones

6

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7 October 2017

W A Lee

7

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7 October 2017

publication date

1 November 1999

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7 October 2017

published in

Pharmaceutical Research

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7 October 2017

volume

16

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7 October 2017

issue

11

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7 October 2017

page(s)

1687-1693

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Pharmacokinetics and bioavailability of the anti-human immunodeficiency virus nucleotide analog 9-[(R)-2-(phosphonomethoxy)propyl]adenine (PMPA) in dogs.

7 October 2017

cites work

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12 December 2020

Conversion of 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine to cidofovir by an intracellular cyclic CMP phosphodiesterase

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12 December 2020

1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl] cytosine, an intracellular prodrug for (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine with improved therapeutic index in vivo

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12 December 2020

Hydrolysis of phosphonate esters catalyzed by 5'-nucleotide phosphodiesterase

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12 December 2020

Pharmacokinetics, bioavailability, metabolism, and tissue distribution of cidofovir (HPMPC) and cyclic HPMPC in rats

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12 December 2020

Enantioselective and reversible inhibition of trypsin and alpha-chymotrypsin by phosphonate esters

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12 December 2020

Neighboring group catalysis in the design of nucleotide prodrugs.

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12 December 2020

Anti-human immunodeficiency virus (HIV) activity, safety, and pharmacokinetics of adefovir dipivoxil (9-[2-(bis-pivaloyloxymethyl)-phosphonylmethoxyethyl]adenine) in HIV-infected patients

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12 December 2020

Enzymic hydrolysis of phosphonate esters. Reaction mechanism of intestinal 5'-nucleotide phosphodiesterase

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12 December 2020

Pharmacokinetics and metabolism of selected prodrugs of PMEA in rats

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12 December 2020

Clinical pharmacokinetics of adefovir in human immunodeficiency virus type 1-infected patients

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12 December 2020

Metabolism and pharmacokinetics of novel oral prodrugs of 9-[(R)-2-(phosphonomethoxy)propyl]adenine (PMPA) in dogs

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12 December 2020

The use of human liver for foreign compound metabolism and toxicity studies

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12 December 2020

Identifiers

DOI

10.1023/A:1018945713623

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7 October 2017

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