(Q41704645)

7 October 2017

title

Effects of major transporter and metabolizing enzyme gene polymorphisms on carbamazepine metabolism in Chinese patients with epilepsy (English)

1 reference

7 October 2017

1 reference

Xu Zhu

1

1 reference

7 October 2017

Wenting Yun

2

1 reference

7 October 2017

Xiaofu Sun

3

1 reference

7 October 2017

Feng Qiu

4

1 reference

7 October 2017

Limei Zhao

5

1 reference

7 October 2017

Yingjie Guo

6

1 reference

7 October 2017

publication date

1 January 2014

1 reference

7 October 2017

1 reference

7 October 2017

volume

15

1 reference

7 October 2017

issue

15

1 reference

7 October 2017

page(s)

1867-1879

1 reference

Genetic variants in microsomal epoxide hydrolase influence carbamazepine dosing.

7 October 2017

cites work

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Transporter biology in drug approval: regulatory aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Gene-wide tagging study of association between ABCB1 polymorphisms and multidrug resistance in epilepsy in Han Chinese

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Carbamazepine is not a substrate for P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

In vitro transport profile of carbamazepine, oxcarbazepine, eslicarbazepine acetate, and their active metabolites by human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Effects of ABCB1 polymorphisms on plasma carbamazepine concentrations and pharmacoresistance in Chinese patients with epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

An epoxidation mechanism of carbamazepine by CYP3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Pathways of carbamazepine bioactivation in vitro I. Characterization of human cytochromes P450 responsible for the formation of 2- and 3-hydroxylated metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

A functional polymorphism in the CYP3A4 gene is associated with increased risk of coronary heart disease in the Chinese Han population.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Impact of the CYP3A5, CYP3A4, COMT, IL-10 and POR genetic polymorphisms on tacrolimus metabolism in Chinese renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Associations of ABCB1, NFKB1, CYP3A, and NR1I2 polymorphisms with cyclosporine trough concentrations in Chinese renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Effects of EPHX1, SCN1A and CYP3A4 genetic polymorphisms on plasma carbamazepine concentrations and pharmacoresistance in Chinese patients with epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Genetic variability in CYP3A5 and its possible consequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Effect of CYP3A5*3 genotype on serum carbamazepine concentrations at steady-state in Korean epileptic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Genetics of P450 oxidoreductase: sequence variation in 842 individuals of four ethnicities and activities of 15 missense mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Effects of the CYP oxidoreductase Ala503Val polymorphism on CYP3A activity in vivo: a randomized, open-label, crossover study in healthy Chinese men.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Impact of POR*28 on the pharmacokinetics of tacrolimus and cyclosporine A in renal transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Non-synonymous single nucleotide alterations in the microsomal epoxide hydrolase gene and their functional effects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Association of carbamazepine major metabolism and transport pathway gene polymorphisms and pharmacokinetics in patients with epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

CYP3A4*1G polymorphism is associated with lipid-lowering efficacy of atorvastatin but not of simvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Association of polymorphisms in EPHX1, UGT2B7, ABCB1, ABCC2, SCN1A and SCN2A genes with carbamazepine therapy optimization.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Association of MDR1 (C3435T) polymorphism and resistance to carbamazepine in epileptic patients from Turkey

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Enzyme induction with antiepileptic drugs: cause for concern?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Evidence of significant contribution from CYP3A5 to hepatic drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Global pharmacogenomics: distribution of CYP3A5 polymorphisms and phenotypes in the Brazilian population

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Substrate-specific modulation of CYP3A4 activity by genetic variants of cytochrome P450 oxidoreductase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Effect of CYP3A4*22, POR*28, and PPARA rs4253728 on sirolimus in vitro metabolism and trough concentrations in kidney transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Peroxidase-mediated bioactivation of hydroxylated metabolites of carbamazepine and phenytoin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Cross-reactivity assessment of carbamazepine-10,11-epoxide, oxcarbazepine, and 10-hydroxy-carbazepine in two automated carbamazepine immunoassays: PETINIA and EMIT 2000.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

Association of CYP3A4*18B polymorphisms with the pharmacokinetics of cyclosporine in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.14.142

21 January 2018

Identifiers

DOI

10.2217/PGS.14.142

1 reference

7 October 2017

1 reference