(Q41719685)

8 October 2017

Dihydroartemisinin targets VEGFR2 via the NF-κB pathway in endothelial cells to inhibit angiogenesis (English)

1 reference

8 October 2017

0 references

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25482945%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Ju Liu

10

1 reference

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11 June 2020

author name string

Fengyun Dong

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25482945%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Xia Zhou

2

1 reference

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11 June 2020

Changsheng Li

3

1 reference

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11 June 2020

Suhua Yan

4

1 reference

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11 June 2020

Xianming Deng

5

1 reference

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11 June 2020

Zhiqun Cao

6

1 reference

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11 June 2020

Liqun Li

7

1 reference

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11 June 2020

Bo Tang

8

1 reference

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11 June 2020

publication date

1 January 2014

1 reference

Cancer Biology and Therapy

8 October 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25482945%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

15

1 reference

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11 June 2020

page(s)

1479-1488

1 reference

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11 June 2020

issue

11

1 reference

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describes a project that uses

11 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4623302/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Topical dihydroartemisinin inhibits suture-induced neovascularization in rat corneas through ERK1/2 and p38 pathways

6 June 2018

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Dihydroartemisinin exhibits antitumor activity toward hepatocellular carcinoma in vitro and in vivo.

6 June 2018

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Antitumor activity of artemisinin and its derivatives: from a well-known antimalarial agent to a potential anticancer drug

6 June 2018

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Molecular mechanisms and clinical applications of angiogenesis

6 June 2018

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Dihydroartemisinin inhibits angiogenesis in pancreatic cancer by targeting the NF-κB pathway.

6 June 2018

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6 June 2018

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Dihydroartemisinin accelerates c-MYC oncoprotein degradation and induces apoptosis in c-MYC-overexpressing tumor cells.

6 June 2018

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Special features of human retinal angiogenesis

6 June 2018

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Dihydroartemisinin improves the efficiency of chemotherapeutics in lung carcinomas in vivo and inhibits murine Lewis lung carcinoma cell line growth in vitro

6 June 2018

1 reference

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Constitutive NF-kappaB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth

6 June 2018

1 reference

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CXCL8/IL8 stimulates vascular endothelial growth factor (VEGF) expression and the autocrine activation of VEGFR2 in endothelial cells by activating NFkappaB through the CBM (Carma3/Bcl10/Malt1) complex

6 June 2018

1 reference

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6 June 2018

1 reference

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Tumor metastasis: mechanistic insights and clinical challenges

6 June 2018

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Angiogenesis as a therapeutic target

6 June 2018

1 reference

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Endothelial cells and VEGF in vascular development

6 June 2018

1 reference

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Angiogenesis in life, disease and medicine

6 June 2018

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Apoptosis of human umbilical vein endothelial cells induced by artesunate

6 June 2018

1 reference

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Artemisinin derivatives: toxic for laboratory animals, safe for humans?

6 June 2018

1 reference

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The biology of VEGF and its receptors

6 June 2018

1 reference

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Heme oxygenase-1-derived carbon monoxide requires the activation of transcription factor NF-kappa B to protect endothelial cells from tumor necrosis factor-alpha-mediated apoptosis

6 June 2018

1 reference

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Transforming growth factor-beta 1-mediated inhibition of the flk-1/KDR gene is mediated by a 5'-untranslated region palindromic GATA site

6 June 2018

1 reference

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Properties of two VEGF receptors, Flt-1 and KDR, in signal transduction

6 June 2018

1 reference

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The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation

6 June 2018

1 reference

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Structure of an IkappaBalpha/NF-kappaB complex

6 June 2018

1 reference

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Mechanisms of angiogenesis

6 June 2018

1 reference

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Biological properties of VEGF/VPF receptors

6 June 2018

1 reference

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Characterization of the endothelium-specific murine vascular endothelial growth factor receptor-2 (Flk-1) promoter

6 June 2018

1 reference

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Regulation of the expression of the VEGF/VPS and its receptors: role in tumor angiogenesis

6 June 2018

1 reference

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Vascular permeability factor (VPF, VEGF) in tumor biology

6 June 2018

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Pyrrolidine dithiocarbamate inhibits NF-kappa B mobilization and TNF production in human monocytes

6 June 2018

1 reference

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flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors.

6 June 2018

1 reference

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Angiogenesis in cancer, vascular, rheumatoid and other disease

6 June 2018

1 reference

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Cloning and functional analysis of the promoter for KDR/flk-1, a receptor for vascular endothelial growth factor

6 June 2018

1 reference

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Qinghaosu (artemisinin): an antimalarial drug from China

6 June 2018

1 reference

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Hypoxia modulates the effect of dihydroartemisinin on endothelial cells.

6 June 2018

1 reference

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In vivo and in vitro investigations of the effects of the antimalarial drug dihydroartemisinin (DHA) on rat embryos.

18 August 2018

1 reference

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Epidermal growth factor activates nuclear factor-kappaB in human proximal tubule cells

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623302

Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623302

Antimalarial dihydroartemisinin also inhibits angiogenesis

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623302

Inhibition of human cancer cell line growth and human umbilical vein endothelial cell angiogenesis by artemisinin derivatives in vitro

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623302

Inhibition of NF-kappa B activity by thalidomide through suppression of IkappaB kinase activity

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623302

The anti-malarial artesunate is also active against cancer

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623302

Pyrrolidine dithiocarbamate prevents I-kappaB degradation and reduces microvascular injury induced by lipopolysaccharide in multiple organs

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623302

Properties of Two VEGF Receptors, Flt-1 and KDR, in Signal Transductiona

18 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2F15384047.2014.955728

Artesunate inhibits angiogenesis and downregulates vascular endothelial growth factor expression in chronic myeloid leukemia K562 cells

21 January 2018

1 reference

12 December 2020

The development of new antimalarial drugs: qinghaosu and dihydro-qinghaosu

1 reference

12 December 2020

Suppression of retinal neovascularization by the NF-kappaB inhibitor pyrrolidine dithiocarbamate in mice

1 reference

12 December 2020

Epidermal growth factor (EGF) activates nuclear factor-kappaB through IkappaBalpha kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IkappaBalpha

1 reference

12 December 2020

Induction of apoptosis and inhibition of cell migration and tube-like formation by dihydroartemisinin in murine lymphatic endothelial cells

1 reference

12 December 2020

IkappaB kinase-alpha regulates endothelial cell motility and tumor angiogenesis

1 reference

12 December 2020

10.4161/15384047.2014.955728

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25482945%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25482945%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference