(Q41730397)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9524060%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

review article

1 reference

title

An active zymogen: unravelling the mystery of tissue-type plasminogen activator (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9524060%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9524060%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author name string

M Renatus

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9524060%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

W Bode

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9524060%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

publication date

1 February 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9524060%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9524060%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

379

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9524060%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9524060%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

page(s)

95-103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9524060%20AND%20SRC:MED&resulttype=core&format=json

The role of the lysyl binding site of tissue-type plasminogen activator in the interaction with a forming fibrin clot

10 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Stromelysin-1: three-dimensional structure of the inhibited catalytic domain and of the C-truncated proenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding. II. The binding of the pancreatic trypsin inhibitor and of isoleucine-valine and of sequentially related peptides to trypsinogen and to p-guanidinobenzoate-tryp

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Crystal structure of bovine trypsinogen at 1-8 A resolution. I. Data collection, application of patterson search techniques and preliminary structural interpretation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Solution structure of the tissue-type plasminogen activator kringle 2 domain complexed to 6-aminohexanoic acid an antifibrinolytic drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-.ANG. resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Solution structure of the fibrin binding finger domain of tissue-type plasminogen activator determined by 1H nuclear magnetic resonance

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

The prosegment-subtilisin BPN' complex: crystal structure of a specific 'foldase'

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Complexation of the tissue plasminogen activator protease with benzamidine-type inhibitors: interference by the kringle 2 module.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Structural basis of the activation and action of trypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

The plasminogen activator family from the salivary gland of the vampire bat Desmodus rotundus: cloning and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Mechanisms of plasminogen activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Proteolytic processing and physiological regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Sites in fibrin involved in the acceleration of plasminogen activation by t-PA. Possible role of fibrin polymerisation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

The structure of the human tissue-type plasminogen activator gene: correlation of intron and exon structures to functional and structural domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Enzymatic properties of the one- and two-chain form of tissue plasminogen activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Structural mapping of the active site specificity determinants of human tissue-type plasminogen activator. Implications for the design of low molecular weight substrates and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Lysine 156 promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single-chain human tPA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Catalytic domain structure of vampire bat plasminogen activator: a molecular paradigm for proteolysis without activation cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

The solution structure and backbone dynamics of the fibronectin type I and epidermal growth factor-like pair of modules of tissue-type plasminogen activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Variants of tissue-type plasminogen activator with substantially enhanced response and selectivity toward fibrin co-factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Protein loop grafting to construct a variant of tissue-type plasminogen activator that binds platelet integrin alpha IIb beta 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Converting tissue type plasminogen activator into a zymogen. Important role of Lys156.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Crystal structures of human procathepsin B at 3.2 and 3.3 Angstroms resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Purification and characterization of a melanoma cell plasminogen activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Testican, a multidomain testicular proteoglycan resembling modulators of cell social behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Transport properties of free and MHC class II-associated oligomers containing different isoforms of human invariant chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Major histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin L

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Proteolytic cleavage of insulin-like growth factor binding protein 4 (IGFBP-4). Localization of cleavage site to non-homologous region of native IGFBP-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Endosomal proteases and antigen processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Evidence for a novel insulin-like growth factor (IGF)-dependent protease regulating IGF-binding protein-4 in dermal fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) functions as an IGF-reversible inhibitor of IGFBP-4 proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Modular structural units, exons, and function in chicken lysozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Phosphorylation of insulin-like growth factor (IGF)-binding protein 1 in cell culture and in vivo: effects on affinity for IGF-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Membrane insertion and oligomeric assembly of HLA-DR histocompatibility antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Primary structure of human thyroglobulin deduced from the sequence of its 8448-base complementary DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

An acid protease secreted by transformed cells interferes with antigen processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Presence of hormonogenic and repetitive domains in the first 930 amino acids of bovine thyroglobulin as deduced from the cDNA sequence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

The type-1 repeats of thyroglobulin regulate thyroglobulin degradation and T3, T4 release in thyrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Molecular cloning of bullfrog saxiphilin: a unique relative of the transferrin family that binds saxitoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Molecular cloning of bullfrog saxiphilin: a unique relative of the transferrin family that binds saxitoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Ascidian entactin/nidogen. Implication of evolution by shuffling two kinds of cysteine-rich motifs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

MHC class II restricted antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Crystal structure of the wild-type human procathepsin B at 2.5 A resolution reveals the native active site of a papain-like cysteine protease zymogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6)

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Two forms of the Ia antigen-associated invariant chain result from alternative initiations at two in-phase AUGs

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Interaction of MHC class II molecules with the invariant chain: role of the invariant chain (81-90) region

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Molecular cloning of cDNA for the carcinoma-associated antigen GA733-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

The cystatins: Protein inhibitors of cysteine proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Antigen presentation by MHC class II molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Identification of two new exons and multiple transcription start points in the 5'-untranslated region of the human cathepsin-B-encoding gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Mannose-6-phosphate receptors for lysosomal enzymes cycle between the Golgi complex and endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Human gastric adenocarcinoma cathepsin B: isolation and sequencing of full-length cDNAs and polymorphisms of the gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Specific mannose-6-phosphate receptor-independent sorting of pro-cathepsin D in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Cystatin C and cathepsin B in human colon carcinoma: expression by cell lines and matrix degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Differentiation-induced changes in the content, secretion, and subcellular distribution of lysosomal cathepsins in the human colon cancer HT-29 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Isolation of a cDNA clone for the human lysosomal proteinase cathepsin B

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Isolation of a cathepsin B-encoding cDNA from murine osteogenic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Characterization of the cathepsin B gene and multiple mRNAs in human tissues: evidence for alternative splicing of cathepsin B pre-mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Cathepsin B expression in tumour cells and laminin distribution in pulmonary adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Macrophage cathepsin L, a factor in the erosion of subchondral bone in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Neither type of mannose 6-phosphate receptor is sufficient for targeting of lysosomal enzymes along intracellular routes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Tumor progression and angiogenesis: cathepsin B & Co.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Endothelial cells and angiogenic growth factors in cancer growth and metastasis. Introduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

The role of cellular proteases and their inhibitors in invasion and metastasis. Introductionary overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Contributions of tumor and stromal matrix metalloproteinases to tumor progression, invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

A possible role for cathepsins D, E, and B in the processing of beta-amyloid precursor protein in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Comparison of cathepsin protease activities in brain tissue from normal cases and cases with Alzheimer's disease, Lewy body dementia, Parkinson's disease and Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Control of type IV collagenase activity by components of the urokinase-plasmin system: a regulatory mechanism with cell-bound reactants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Xenograft model of progressive human proliferative breast disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

The glycosylation state of the precursors of the cathepsin B-like proteinase from human malignant ascitic fluid: possible implication in the secretory pathway of these proenzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Lysosomes behave as Ca2+-regulated exocytic vesicles in fibroblasts and epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Localization of a biotinylated cathepsin B oligonucleotide probe in human prostate including invasive cells and invasive edges by in situ hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Cathepsin B in angiogenesis of human prostate: an immunohistochemical and immunoelectron microscopic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Overexpression and localization of cathepsin B during the progression of human gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Differential secretion of cathepsins B and L from normal and tumor human lung cells stimulated by 12(S)-hydroxy-eicosatetraenoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Changes in the expression of elastase and cathepsin B with differentiation of U937 promonocytes by GMCSF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Cathepsin B fraction active at physiological pH of 7.5 is of prognostic significance in squamous cell carcinoma of human lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Emerging roles for cysteine proteases in human biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Changes in lysosome shape and distribution correlated with changes in cytoplasmic pH

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Stefins and lysosomal cathepsins B, L and D in human breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Cathepsins D, B, and L in transformed human breast epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Enzyme-linked immunosorbent assay for the detection of total cathepsin H in human tissue cytosols and sera

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Structure of the human insulin-like growth factor binding protein-2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Phorbol ester tumor promoters regulate insulin-like growth factor- binding protein-4 proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Cathepsin B and L activities in isolated osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

Differences in secretion of the proteinase cathepsin B at the edges of human breast carcinomas and fibroadenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBCHM.1998.379.2.95

10.1515/BCHM.1998.379.2.95

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9524060%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference