(Q41731369)

8 October 2017

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title

The role of transforming growth factor beta in glioma progression (English)

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8 October 2017

Jennings MT

1

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8 October 2017

Pietenpol JA

series ordinal

2

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8 October 2017

publication date

1 January 1998

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Journal of Neuro-Oncology

8 October 2017

published in

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8 October 2017

volume

36

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8 October 2017

issue

2

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8 October 2017

page(s)

123-140

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Transforming growth factor-beta in neural embryogenesis and neoplasia

8 October 2017

cites work

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12 December 2020

Cyclin D1 oncoprotein aberrantly accumulates in malignancies of diverse histogenesis

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12 December 2020

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1 reference

12 December 2020

Agents that increase cAMP accumulation block endothelial c-sis induction by thrombin and transforming growth factor-beta

1 reference

12 December 2020

The retinoblastoma gene is involved in malignant progression of astrocytomas

1 reference

12 December 2020

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

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12 December 2020

Platelet-derived growth factor receptor-beta is induced during tumor development and upregulated during tumor progression in endothelial cells in human gliomas

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12 December 2020

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

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12 December 2020

Transforming growth factor-betas inhibit mitogen-stimulated proliferation of astrocytes

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12 December 2020

Transforming growth factors type beta 1 and beta 2 suppress rat astrocyte autoantigen presentation and antagonize hyperinduction of class II major histocompatibility complex antigen expression by interferon-gamma and tumor necrosis factor-alpha

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12 December 2020

Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family

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12 December 2020

Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta.

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12 December 2020

Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells

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12 December 2020

Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases

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12 December 2020

Expression of platelet-derived growth factor and transforming growth factor and their correlation with cellular morphology in glial tumors

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12 December 2020

Receptors for transforming growth factor-beta.

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12 December 2020

Transforming growth factor beta-treated normal fibroblasts eliminate transformed fibroblasts by induction of apoptosis

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12 December 2020

Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential

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12 December 2020

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

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12 December 2020

p53 mutation, expression, and DNA ploidy in evolving gliomas: evidence for two pathways of progression.

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12 December 2020

Transforming growth factor-beta 1 inhibits the proliferation of rat astrocytes induced by serum and growth factors

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12 December 2020

Transforming growth factor beta and cell cycle regulation

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12 December 2020

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

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12 December 2020

The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis.

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12 December 2020

CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas.

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12 December 2020

Interaction of acidic fibroblast growth factor and transforming growth factor-beta in normal and transformed glia in vitro

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12 December 2020

A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance

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12 December 2020

The effect of transforming growth factor-beta 2-specific phosphorothioate-anti-sense oligodeoxynucleotides in reversing cellular immunosuppression in malignant glioma

1 reference

12 December 2020

TGF beta 1 and TGF beta 2 are potential growth regulators for medulloblastomas, primitive neuroectodermal tumors, and ependymomas: evidence in support of an autocrine hypothesis

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12 December 2020

Differential effects of epidermal growth factor, transforming growth factor, and insulin on DNA and protein synthesis and morphology in serum-free cultures of AKR-2B cells

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12 December 2020

Mutant p53 tumor suppressor gene causes resistance to transforming growth factor beta 1 in murine keratinocytes

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12 December 2020

Transforming growth factor-beta inhibits phosphorylation of the retinoblastoma susceptibility gene product in human monocytic leukemia cell line JOSK-I.

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12 December 2020

TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains.

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12 December 2020

Resistance to tgf-Beta-induced elimination of transformed-cells is required during tumor progression (review-hypothesis).

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12 December 2020

Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B.

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12 December 2020

Absence of p16INK4 protein is restricted to the subset of lung cancer lines that retains wildtype RB

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12 December 2020

Stabilised p53 facilitates aneuploid clonal divergence in colorectal cancer

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12 December 2020

Responsiveness to transforming growth factor-beta (TGF-beta) restored by genetic complementation between cells defective in TGF-beta receptors I and II

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12 December 2020

Mitogenic effect of transforming growth factor beta 1 on human fibroblasts involves the induction of platelet-derived growth factor alpha receptors

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12 December 2020

The retinoblastoma protein and cell cycle control

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12 December 2020

Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis

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12 December 2020

Tumor-promoting activity of Epstein-Barr-virus-inducing factor transforming growth factor type beta (EIF/TGF-beta) is due to the induction of irreversible transformation

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12 December 2020

High levels of transforming growth factor beta 1 correlate with disease progression in human colon cancer

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12 December 2020

Transforming growth factor beta 1 can induce estrogen-independent tumorigenicity of human breast cancer cells in athymic mice

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12 December 2020

A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells

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12 December 2020

Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells

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12 December 2020

Effects of transforming growth factor-beta 1 on collagen synthesis, integrin expression, adhesion and invasion of glioma cells.

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12 December 2020

Transforming growth factor-beta 1 inhibits cyclin D1 expression in intestinal epithelial cells

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12 December 2020

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

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12 December 2020

Retinoic acid induces secretion of latent transforming growth factor beta 1 and beta 2 in normal and human papillomavirus type 16-immortalized human keratinocytes

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12 December 2020

Inhibition of ras-induced proliferation and cellular transformation by p16INK4.

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12 December 2020

Activation of p21ras by transforming growth factor beta in epithelial cells

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12 December 2020

Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer

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12 December 2020

Retinoblastoma gene deletions in human glioblastomas

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12 December 2020

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

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12 December 2020

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

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12 December 2020

Enhanced expression of transforming growth factor‐β and its type‐I and type‐II receptors in human glioblastoma

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12 December 2020

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization

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12 December 2020

Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation

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12 December 2020

Stimulatory role of transforming growth factors in multistage skin carcinogenesis: possible explanation for the tumor-inducing effect of wounding in initiated NMRI mouse skin

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12 December 2020

Molecular genetics of human glioma

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12 December 2020

TGF-beta induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop

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12 December 2020

Phenotypic alterations in fibroblasts and fibrosarcoma cells that overexpress latent transforming growth factor-beta 1

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12 December 2020

Direct transforming activity of TGF-beta on rat fibroblasts

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12 December 2020

Type beta transforming growth factor/growth inhibitor stimulates entry of monolayer cultures of AKR-2B cells into S phase after a prolonged prereplicative interval

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12 December 2020

Transforming growth factor beta-induced activation of cyclin E-cdk2 kinase and down-regulation of p27Kip1 in C3H 10T1/2 mouse fibroblasts

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12 December 2020

Control of astrocytosis by interleukin-1 and transforming growth factor-beta 1 in human brain

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12 December 2020

Absence of TGF-beta receptors and growth inhibitory responses in retinoblastoma cells

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12 December 2020

Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin

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12 December 2020

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues

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12 December 2020

Expression of multi-cytokine resistance and multi-growth factor independence in advanced stage metastatic cancer. Malignant melanoma as a paradigm

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12 December 2020

Development of resistance mechanisms to the growth-inhibitory effects of transforming growth factor-beta during tumor progression

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12 December 2020

TGF-beta induces an inhibitory effect of normal cells directed against transformed cells

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12 December 2020

TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest

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12 December 2020

Human Brain Tumors and Simian Virus 40

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12 December 2020

Enhanced jun gene expression is an early genomic response to transforming growth factor beta stimulation

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12 December 2020

Distribution of transforming growth factor-beta 1 in human astrocytomas

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12 December 2020

DNA index and S-phase in primary brain tumors. A comparison between fresh and deparaffinized specimens studied by flow cytometry.

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12 December 2020

Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor beta 1

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12 December 2020

How many mutations are required for tumorigenesis? Implications from human cancer data

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12 December 2020

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12 December 2020

TGF-beta stimulates primary human skin fibroblast DNA synthesis via an autocrine production of PDGF-related peptides

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12 December 2020

Evidence that transforming growth factor-beta is a hormonally regulated negative growth factor in human breast cancer cells

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12 December 2020

Stimulation of hyaluronan biosynthesis by platelet-derived growth factor-BB and transforming growth factor-beta 1 involves activation of protein kinase C.

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12 December 2020

The glioblastoma-derived T-cell suppressor factor/transforming growth factor beta 2 inhibits the generation of lymphokine-activated killer (LAK) cells.

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12 December 2020

p53 mutations in human malignant gliomas: comparison of loss of heterozygosity with mutation frequency

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12 December 2020

Transforming growth factor production by chemically transformed cells

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12 December 2020

Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation

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12 December 2020

Transforming growth factor beta 1 inhibition of p34cdc2 phosphorylation and histone H1 kinase activity is associated with G1/S-phase growth arrest

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12 December 2020

Transforming growth factor beta 1 treatment of AKR-2B cells is coupled through a pertussis-toxin-sensitive G-protein(s).

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12 December 2020

Immunophenotypic differences between normal glia, astrocytomas and malignant gliomas: correlations with karyotype, natural history and survival.

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12 December 2020

Regulation of platelet-derived growth factor gene expression by transforming growth factor beta and phorbol ester in human leukemia cell lines

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12 December 2020

Absence of WAF1 mutations in a variety of human malignancies

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12 December 2020

The tumor suppressor protein p53: a receptor to genotoxic stress that controls cell growth and survival

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12 December 2020

Pathways leading to glioblastoma multiforme: a molecular analysis of genetic alterations in 65 astrocytic tumors.

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12 December 2020

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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12 December 2020

Suppressive effect of transforming growth factor-beta on the phosphorylation of endogenous substrates by conventional and novel protein kinase C in primary cultured mouse epidermal cells

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12 December 2020

Colon carcinoma cells switch their response to transforming growth factor beta 1 with tumor progression

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12 December 2020

The effects of type beta transforming growth factor on proliferation and epidermal growth factor receptor expression in a human glioblastoma cell line

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12 December 2020

Growth Factor Synthesis and Human Breast Cancer Progression

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12 December 2020

Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts

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12 December 2020

Overexpression of human cyclin D1 reduces the transforming growth factor beta (TGF-beta) type II receptor and growth inhibition by TGF-beta 1 in an immortalized human esophageal epithelial cell line

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12 December 2020

Analysis of the p53 gene and its expression in human glioblastoma cells

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12 December 2020

Mutation of the p53 gene in human soft tissue sarcomas: association with abnormalities of the RB1 gene.

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12 December 2020

Transforming growth factor-beta 1 regulates platelet-derived growth factor receptor beta subunit in human liver fat-storing cells

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12 December 2020

Participation of p53 protein in the cellular response to DNA damage

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12 December 2020

Interaction between p53 and TGF beta 1 in control of epithelial cell proliferation.

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12 December 2020

Modifications of cell cycle controlling nuclear proteins by transforming growth factor beta in the HaCaT keratinocyte cell line.

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12 December 2020

Immunosuppression and transforming growth factor-beta in glioblastoma. Preferential production of transforming growth factor-beta 2.

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12 December 2020

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

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12 December 2020

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12 December 2020

TGF beta signals through a heteromeric protein kinase receptor complex

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12 December 2020

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

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12 December 2020

Transforming growth factor beta-1 positively modulates the bioactivity of fibroblast growth factor on corneal endothelial cells

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12 December 2020

Loss of growth factor dependence and conversion of transforming growth factor-beta 1 inhibition to stimulation in metastatic H-ras-transformed murine fibroblasts.

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12 December 2020

Alterations of the TP53 gene in human gliomas

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12 December 2020

Targeting TGF-beta for treatment of disease

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12 December 2020

Lack of correlation between sensitivity to growth inhibition and receptor number for transforming growth factor beta in human squamous carcinoma cell lines

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12 December 2020

Overexpression of multiple oncogenes related to histological grade of astrocytic glioma

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12 December 2020

p53-mediated apoptosis in HeLa cells can be overcome by excess pRB

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12 December 2020

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

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12 December 2020

Differential effects of transforming growth factor beta 1 on the growth of poorly and highly metastatic murine melanoma cells

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12 December 2020

Differential regulation of expression of two platelet-derived growth factor receptor subunits by transforming growth factor-beta

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12 December 2020

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

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12 December 2020

Transforming growth factor β1 is a powerful modulator of platelet‐derived growth factor action in vascular smooth muscle cells

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12 December 2020

Transforming growth factor beta isoform-specific differences in interactions with type I and II transforming growth factor beta receptors

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12 December 2020

TGF beta 1 and TGF beta 2 are potential growth regulators for low-grade and malignant gliomas in vitro: evidence in support of an autocrine hypothesis

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12 December 2020

Effect of transforming growth factor-beta 1 on platelet-derived growth factor receptor binding and gene expression in vascular smooth muscle cells from SHR and WKY rats.

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12 December 2020

Control of human glioma cell growth, migration and invasion in vitro by transforming growth factor beta 1

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12 December 2020

Transforming growth factor beta as a potent promoter in two-stage BALB/c 3T3 cell transformation.

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12 December 2020

TGF-beta stimulation and inhibition of cell proliferation: new mechanistic insights

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12 December 2020

T cell suppressor factor from human glioblastoma cells is a 12.5-kd protein closely related to transforming growth factor-beta

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12 December 2020

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

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12 December 2020

Inactivation of the retinoblastoma gene does not lead to loss of TGF-beta receptors or response to TGF-beta in breast cancer cell lines

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12 December 2020

Transforming growth factor beta stimulates phosphoinositol metabolism and translocation of protein kinase C in cultured astrocytes

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12 December 2020

Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor

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12 December 2020

Allelotype of human malignant astrocytoma.

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12 December 2020

Transforming growth factor-beta induces platelet-derived growth factor (PDGF) messenger RNA and PDGF secretion while inhibiting growth in normal human mammary epithelial cells

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12 December 2020

Control of the expression of c-sis mRNA in human glioblastoma cells by phorbol ester and transforming growth factor beta 1.

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12 December 2020

Reduction of TGF-beta activity abrogates growth promoting tumor cell-cell interactions in vivo

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12 December 2020

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

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12 December 2020

Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-beta activities.

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12 December 2020

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin

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12 December 2020

Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition

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12 December 2020

Loss of transforming growth factor beta 1 (TGF-beta 1)-induced growth arrest and p34cdc2 regulation in ras-transfected epithelial cells

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12 December 2020

Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect

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12 December 2020

Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity

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12 December 2020

Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies

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12 December 2020

Increased transforming growth factor beta expression inhibits cell proliferation in vitro, yet increases tumorigenicity and tumor growth of Meth A sarcoma cells.

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12 December 2020

Clonal expansion of p53 mutant cells is associated with brain tumour progression

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12 December 2020

Introduction of v-Ha-ras oncogene induces differentiation of cultured human medullary thyroid carcinoma cells

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12 December 2020

Effects of transforming growth factor beta 1 on astroglial cells in culture

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12 December 2020

Chromosomal evolution in malignant human gliomas starts with specific and usually numerical deviations

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12 December 2020

The properties of p53 proteins selected for the loss of suppression of transformation.

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12 December 2020

Induction of transforming growth factor beta 1 resistance by the E1A oncogene requires binding to a specific set of cellular proteins.

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12 December 2020

Deletion of p16 and p15 genes in brain tumors

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12 December 2020

Clonal genomic alterations in glioma malignancy stages.

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12 December 2020

Cdk4 integrates growth stimulatory and inhibitory signals during G1 phase of hematopoietic cells

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12 December 2020

A cell cycle regulator potentially involved in genesis of many tumor types

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12 December 2020

Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations.

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12 December 2020

A correlative study of p53 protein alteration and p53 gene mutation in glioblastoma multiforme

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12 December 2020

Immunocytochemical study of transforming growth factor expression in benign and malignant gliomas.

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12 December 2020

Identifiers

DOI

10.1023/A:1005863419880

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Dimensions Publication ID

8 October 2017

1012940370

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